BC-spiro-estradiols. Synthesis and estrogen receptor binding affinity of four new estradiol isomers

Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 11, 2012, Pages 3713-3717

  Asim, Muhammad ^a   Klonowska, Daria ^a   Choueiri, Christine ^a   Korobkov, Ilia ^a   Carlson, Kathryn E ^b   Katzenellenbogen, John A ^b   Durst, Tony ^a  

^a UNIVERSITY OF OTTAWA   (Canada)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

BC spiro estrogen; ER binding affinity; Estradiol; Synthesis

Indexed keywords

ESTRADIOL; ESTRADIOL DERIVATIVE; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; HETEROCYCLIC COMPOUND; SPIRO COMPOUND;

ARTICLE; BINDING AFFINITY; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; HUMAN; ISOMER; STEREOCHEMISTRY;

ESTRADIOL; HETEROCYCLIC COMPOUNDS; ISOMERISM; PROTEIN BINDING; RECEPTORS, ESTROGEN; SPIRO COMPOUNDS;

EID: 84861190947     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2012.04.022     Document Type: Article

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