PEGylation for drug delivery to ischemic myocardium: Pharmacokinetics and cardiac distribution of poly(ethylene glycol)s in mice with normal and ischemic myocardium

European Journal of Pharmaceutical Sciences

Volumn 46, Issue 5, 2012, Pages 545-552

  Sun, Guilan ^a   Lin, Xiao ^a   Hong, Yanlong ^a   Feng, Yi ^a   Ruan, Kefeng ^a   Xu, Desheng ^a,b  

^a SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b Shuguang Hospital   (China)

Author keywords

Cardiac distribution; EPR effect; Myocardial ischemia; Pharmacokinetics; Poly(ethylene glycol)

Indexed keywords

FLUORESCEIN ISOTHIOCYANATE; MACROGOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; AREA UNDER THE CURVE; ARTICLE; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; HEART MUSCLE ISCHEMIA; MALE; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PEGYLATION; PRIORITY JOURNAL;

ANIMALS; AREA UNDER CURVE; CHEMISTRY, PHARMACEUTICAL; DISEASE MODELS, ANIMAL; DRUG CARRIERS; FLUORESCEIN-5-ISOTHIOCYANATE; MALE; MICE; MOLECULAR WEIGHT; MYOCARDIAL ISCHEMIA; MYOCARDIUM; PERMEABILITY; POLYETHYLENE GLYCOLS; TECHNOLOGY, PHARMACEUTICAL; TISSUE DISTRIBUTION;

EID: 84861185851     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2012.04.010     Document Type: Article

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