Comparison of tissue distribution of a PEGylated Radix Ophiopogonis polysaccharide in mice with normal and ischemic myocardium

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 79, Issue 3, 2011, Pages 621-626

  Lin, Xiao ^a   Wang, Zhuo Jun ^a   Wang, Shuo ^a   Shen, Lan ^a   Feng, Yi ^a   Ruan, Ke Feng ^a   Xu, De Sheng ^a  

^a SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

EPR effect; Myocardial ischemia; PEGylation; Radix Ophiopogonis polysaccharide; Tissue distribution

Indexed keywords

HYDROXYL GROUP; OPHIOPOGON ROOT; PEGYLATED RADIX OPHIOPOGONIS POLYSACCHARIDE; POLYSACCHARIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; BRAIN; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG PENETRATION; DRUG RETENTION; HEART; HEART MUSCLE ISCHEMIA; KIDNEY; LIVER; LUNG; MOUSE; NONHUMAN; TISSUE DISTRIBUTION;

ANIMALS; DISEASE MODELS, ANIMAL; DRUG CARRIERS; METABOLIC CLEARANCE RATE; MICE; MICE, INBRED STRAINS; MYOCARDIAL ISCHEMIA; OPHIOPOGON; ORGAN SPECIFICITY; POLYETHYLENE GLYCOLS; POLYSACCHARIDES; REPRODUCIBILITY OF RESULTS; TISSUE DISTRIBUTION;

EID: 80054001568     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2011.07.002     Document Type: Article

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