Poly(ethylene glycol)-Radix Ophiopogonis polysaccharide conjugates: Preparation, characterization, pharmacokinetics and in vitro bioactivity

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 76, Issue 2, 2010, Pages 230-237

  Lin, Xiao ^a   Wang, Shuo ^a   Jiang, Yan ^b   Wang, Zhuo Jun ^a   Sun, Gui Lan ^a   Xu, De Sheng ^b   Feng, Yi ^a   Shen, Lan ^a  

^a SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b Shuguang Hospital   (China)

Author keywords

Cytoprotection; Elimination half life; Polyethylene glycol; Radix Ophiopogonis polysaccharide; Tube formation

Indexed keywords

FRUCTAN; HYDROXYL GROUP; MACROGOL; POLYSACCHARIDE; RADIX OPHIOPOGONIS POLYSACCHARIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONJUGATE; CONJUGATION; CONTROLLED STUDY; CROSS COUPLING REACTION; DRUG CLEARANCE; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG HALF LIFE; DRUG PURIFICATION; DRUG SYNTHESIS; FEASIBILITY STUDY; HUMAN; HUMAN CELL; IN VITRO STUDY; MALE; MOLECULAR WEIGHT; NONHUMAN; RAT; URINARY EXCRETION;

ANIMALS; CELLS, CULTURED; ENDOTHELIAL CELLS; FEASIBILITY STUDIES; HALF-LIFE; HUMANS; MALE; MOLECULAR WEIGHT; OPHIOPOGON; PLANT EXTRACTS; POLYETHYLENE GLYCOLS; POLYSACCHARIDES; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS;

EID: 77957269310     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2010.07.003     Document Type: Article

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