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Volumn 58, Issue 3, 2012, Pages 121-128

Kisspeptins and the control of gonadotrophin secretion

Author keywords

Absent puberty; Delayed puberty; GPR54; HPG axis; Hypogonadotrophic hypogonadism; KiSS 1; Kisspeptins; Precocious puberty

Indexed keywords

G PROTEIN COUPLED RECEPTOR 54; GONADORELIN; GONADOTROPIN; HORMONE ANTAGONIST; KISSPEPTIN; KISSPEPTIN 10; KISSPEPTIN AGONIST; KISSPEPTIN PEPTIDE 234; PLACEBO; UNCLASSIFIED DRUG;

EID: 84861124215     PISSN: 19396368     EISSN: 19396368     Source Type: Journal    
DOI: 10.3109/19396368.2011.651555     Document Type: Review
Times cited : (41)

References (69)
  • 2
    • 34547113349 scopus 로고    scopus 로고
    • KiSS-1 peptide induces release of LH by a direct effect on the hypothalamus of ovariectomized ewes
    • DOI 10.1016/j.anireprosci.2006.09.021, PII S037843200600457X
    • Arreguin-Arevalo, J.A., Lents, C.A., Farmerie, T.A., Nett, T.M. and Clay, C.M. (2007) KiSS-1 peptide induces release of LH by adirect effect on the hypothalamus of ovariectomized ewes. Anim Reprod Sci 101:265-275. (Pubitemid 47102039)
    • (2007) Animal Reproduction Science , vol.101 , Issue.3-4 , pp. 265-275
    • Arreguin-Arevalo, J.A.1    Lents, C.A.2    Farmerie, T.A.3    Nett, T.M.4    Clay, C.M.5
  • 3
    • 70349448424 scopus 로고    scopus 로고
    • The genetic and molecular basis of idiopathic hypogonadotropic hypogonadism
    • Bianco, S.D.C. and Kaiser, U.B. (2009) The genetic and molecular basis of idiopathic hypogonadotropic hypogonadism. Nat Rev Endocrinol 5:569-576.
    • (2009) Nat Rev Endocrinol , vol.5 , pp. 569-576
    • Bianco, S.D.C.1    Kaiser, U.B.2
  • 8
    • 70949094457 scopus 로고    scopus 로고
    • Kisspeptin/Gpr54-independent gonadotrophin-releasing hormone activity in Kiss1 and Gpr54 mutant mice
    • Chan, Y.M., Broder-Fingert, S., Wong, K.M. and Seminara, S.B. (2009) Kisspeptin/Gpr54-Independent Gonadotrophin-Releasing Hormone Activity in Kiss1 and Gpr54 Mutant Mice. J Neuroendocrinol 21:1015-1023.
    • (2009) J Neuroendocrinol , vol.21 , pp. 1015-1023
    • Chan, Y.M.1    Broder-Fingert, S.2    Wong, K.M.3    Seminara, S.B.4
  • 11
    • 7444245085 scopus 로고    scopus 로고
    • GPR54 and puberty
    • DOI 10.1016/j.tem.2004.09.008, PII S1043276004002188
    • Colledge, W.H. (2004) GPR54 and puberty. Trends Endocrinol Metab 15:448-453. (Pubitemid 39440728)
    • (2004) Trends in Endocrinology and Metabolism , vol.15 , Issue.9 , pp. 448-453
    • Colledge, W.H.1
  • 16
    • 47949125934 scopus 로고    scopus 로고
    • Kisspeptin can stimulate gonadotropin-releasing hormone (GnRH) release by a direct action at GnRH nerve terminals
    • de Tassigny, X.D., Fagg, L.A., Carlton, M.B.L. and Colledge, W.H. (2008) Kisspeptin can stimulate gonadotropin-releasing hormone (GnRH) release by a direct action at GnRH nerve terminals. Endocrinology 149:3926-3932.
    • (2008) Endocrinology , vol.149 , pp. 3926-3932
    • De Tassigny, X.D.1    Fagg, L.A.2    Carlton, M.B.L.3    Colledge, W.H.4
  • 17
    • 48049091828 scopus 로고    scopus 로고
    • Kisspeptin: A novel regulator of reproductive function
    • Dhillo, W.S. (2008) Kisspeptin: A novel regulator of reproductive function. J Neuroendocrinol 20:963-970.
    • (2008) J Neuroendocrinol , vol.20 , pp. 963-970
    • Dhillo, W.S.1
  • 21
    • 42449102751 scopus 로고    scopus 로고
    • A review of Kallmann syndrome: Genetics, pathophysiology, and clinical management
    • DOI 10.1097/OGX.0b013e3181641278, PII 0000625420080300000023
    • Fechner, A., Fong, S. and McGovern, P. (2008) A review of Kallmann syndrome: Genetics, pathophysiology, and clinical management. Obstet Gynecol Surv 63:189-194. (Pubitemid 351612437)
    • (2008) Obstetrical and Gynecological Survey , vol.63 , Issue.3 , pp. 189-194
    • Fechner, A.1    Fong, S.2    McGovern, P.3
  • 22
    • 53749102879 scopus 로고    scopus 로고
    • Kisspeptin and KISS1R: A critical pathway in the reproductive system
    • Gianetti, E. and Seminara, S. (2008) Kisspeptin and KISS1R: a critical pathway in the reproductive system. Reproduction 136:295-301.
    • (2008) Reproduction , vol.136 , pp. 295-301
    • Gianetti, E.1    Seminara, S.2
  • 25
    • 0018057343 scopus 로고
    • Hormone receptor interactions at the cell membrane
    • Hollenberg, M.D. (1978) Hormone receptor interactions at the cell membrane. Pharmacol Rev 30:393-410. (Pubitemid 10186575)
    • (1978) Pharmacological Reviews , vol.30 , Issue.4 , pp. 393-410
    • Hollenberg, M.D.1
  • 28
    • 57849139694 scopus 로고    scopus 로고
    • Kisspeptins and the control of gonadotropin secretion in humans
    • Jayasena, C.N., Dhillo, W.S. and Bloom, S.R. (2009a) Kisspeptins and the control of gonadotropin secretion in humans. Peptides 30:76-82.
    • (2009) Peptides , vol.30 , pp. 76-82
    • Jayasena, C.N.1    Dhillo, W.S.2    Bloom, S.R.3
  • 29
    • 78449307913 scopus 로고    scopus 로고
    • Twice-weekly administration of kisspeptin- 54 for 8 weeks stimulates release of reproductive hormones in women with hypothalamic amenorrhea
    • Jayasena, C.N., Nijher, G.M., Abbara, A., Murphy, K.G., Lim, A., Patel, D., et al. (2010) Twice-weekly administration of kisspeptin- 54 for 8 weeks stimulates release of reproductive hormones in women with hypothalamic amenorrhea. Clin Pharmacol Ther 88:840-847.
    • (2010) Clin Pharmacol Ther , vol.88 , pp. 840-847
    • Jayasena, C.N.1    Nijher, G.M.2    Abbara, A.3    Murphy, K.G.4    Lim, A.5    Patel, D.6
  • 30
    • 70449111663 scopus 로고    scopus 로고
    • Subcutaneous injection of kisspeptin-54 acutely stimulates gonadotropin secretion in women with hypothalamic amenorrhea, but chronic administration causes tachyphylaxis
    • Jayasena, C.N., Nijher, G.M.K., Chaudhri, O.B., Murphy, K.G., Ranger, A., Lim, A., et al. (2009b) Subcutaneous Injection of Kisspeptin-54 Acutely Stimulates Gonadotropin Secretion in Women with Hypothalamic Amenorrhea, But Chronic Administration Causes Tachyphylaxis. J Clin Endocrinol Metab 94:4315-4323.
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 4315-4323
    • Jayasena, C.N.1    Nijher, G.M.K.2    Chaudhri, O.B.3    Murphy, K.G.4    Ranger, A.5    Lim, A.6
  • 31
    • 70350443234 scopus 로고    scopus 로고
    • Sex differences in the regulation of Kiss1/NKB neurons in juvenile mice: Implications for the timing of puberty
    • Kauffman, A.S., Navarro, V.M., Kim, J., Clifton, D.K. and Steiner, R.A. (2009) Sex differences in the regulation of Kiss1/NKB neurons in juvenile mice: implications for the timing of puberty. Am J Physiol Endocrinol Metab 297:E1212-E1221.
    • (2009) Am J Physiol Endocrinol Metab , vol.297
    • Kauffman, A.S.1    Navarro, V.M.2    Kim, J.3    Clifton, D.K.4    Steiner, R.A.5
  • 32
    • 77957277596 scopus 로고    scopus 로고
    • Kisspeptin Directly Regulates Neuropeptide y Synthesis and Secretion via the ERK1/2 and p38 Mitogen-Activated Protein Kinase Signaling Pathways in NPY-Secreting Hypothalamic Neurons
    • Kim, G.L., Dhillon, S.S. and Belsham, D.D. (2010) Kisspeptin Directly Regulates Neuropeptide Y Synthesis and Secretion via the ERK1/2 and p38 Mitogen-Activated Protein Kinase Signaling Pathways in NPY-Secreting Hypothalamic Neurons. Endocrinology 151:5038-5047.
    • (2010) Endocrinology , vol.151 , pp. 5038-5047
    • Kim, G.L.1    Dhillon, S.S.2    Belsham, D.D.3
  • 33
    • 0035860778 scopus 로고    scopus 로고
    • The metastasis suppressor gene KiSS-1 encodes kisspeptins, the natural ligands of the orphan G protein-coupled receptor GPR54
    • Kotani, M., Detheux, M., Vandenbbogaerde, A., Communi, D., Vanderwinden, J.M., Le Poul, E., et al. (2001) The metastasis suppressor gene KiSS-1 encodes kisspeptins, the natural ligands of the orphan G protein-coupled receptor GPR54. J Biol Chem 276:34631-34636.
    • (2001) J Biol Chem , vol.276 , pp. 34631-34636
    • Kotani, M.1    Detheux, M.2    Vandenbbogaerde, A.3    Communi, D.4    Vanderwinden, J.M.5    Le Poul, E.6
  • 34
    • 29644447614 scopus 로고    scopus 로고
    • Role of sequence variations of the GnRH receptor and G protein-coupled receptor 54 gene in male idiopathic hypogonadotropic hypogonadism
    • DOI 10.1530/eje.1.02031
    • Lanfranco, F., Gromoll, J., von Eckardstein, S., Herding, E.M., Nieschlag, E. and Simoni, M. (2005) Role of sequence variations of the GnRH receptor and G protein-coupled receptor 54 gene in male idiopathic hypogonadotropic hypogonadism. Eur J Endocrinol 153:845-852. (Pubitemid 43020235)
    • (2005) European Journal of Endocrinology , vol.153 , Issue.6 , pp. 845-852
    • Lanfranco, F.1    Gromoll, J.2    Von Eckardstein, S.3    Herding, E.M.4    Nieschlag, E.5    Simoni, M.6
  • 38
    • 77954073022 scopus 로고    scopus 로고
    • Kisspeptin signalling in the hypothalamic arcuate nucleus regulates GnRH pulse generator frequency in the rat
    • Li, X.F., Kinsey-Jones, J.S., Cheng, Y., Knox, A.M., Lin, Y., Petrou, N. A., et al. (2009) Kisspeptin signalling in the hypothalamic arcuate nucleus regulates GnRH pulse generator frequency in the rat. PLoS One 4:e8334.
    • (2009) PLoS One , vol.4
    • Li, X.F.1    Kinsey-Jones, J.S.2    Cheng, Y.3    Knox, A.M.4    Lin, Y.5    Petrou, N.A.6
  • 40
    • 57249095669 scopus 로고    scopus 로고
    • Comparison of the effects of peripherally administered kisspeptins
    • Mikkelsen, J.D., Bentsen, A.H., Ansel, L., Simonneaux, V. and Juul, A. (2009) Comparison of the effects of peripherally administered kisspeptins. Regul Pept 152:95-100.
    • (2009) Regul Pept , vol.152 , pp. 95-100
    • Mikkelsen, J.D.1    Bentsen, A.H.2    Ansel, L.3    Simonneaux, V.4    Juul, A.5
  • 41
    • 78649510825 scopus 로고    scopus 로고
    • Kisspeptin antagonists: Unraveling the role of kisspeptin in reproductive physiology
    • Millar, R.P., Roseweir, A.K., Tello, J.A., Anderson, R.A., George, J.T., Morgan, K., et al. (2010) Kisspeptin antagonists: Unraveling the role of kisspeptin in reproductive physiology. Brain Res 1364:81-89.
    • (2010) Brain Res , vol.1364 , pp. 81-89
    • Millar, R.P.1    Roseweir, A.K.2    Tello, J.A.3    Anderson, R.A.4    George, J.T.5    Morgan, K.6
  • 43
    • 4644289298 scopus 로고    scopus 로고
    • Developmental and hormonally regulated messenger ribonucleic acid expression of KiSS-1 and its putative receptor, GPR54, in rat hypothalamus and potent luteinizing hormone-releasing activity of KiSS-1 peptide
    • DOI 10.1210/en.2004-0413
    • Navarro, V.M., Castellano, J.M., Fernandez-Fernandez, R., Barreiro, M.L., Roa, J., Sanchez-Criado, J.E., et al. (2004a) Developmental and hormonally regulated messenger ribonucleic acid expression of KiSS-1 and its putative receptor, GPR54, in rat hypothalamus and potent luteinizing hormone-releasing activity of KiSS-1 peptide. Endocrinology 145:4565-4574. (Pubitemid 39281449)
    • (2004) Endocrinology , vol.145 , Issue.10 , pp. 4565-4574
    • Navarro, V.M.1    Castellano, J.M.2    Fernandez-Fernandez, R.3    Barreiro, M.L.4    Roa, J.5    Sanchez-Criado, J.E.6    Aguilar, E.7    Dieguez, C.8    Pinilla, L.9    Tena-Sempere, M.10
  • 48
    • 33745928176 scopus 로고    scopus 로고
    • Neuroendocrine, gonadal, placental, and obstetric phenotypes in patients with IHH and mutations in the G-protein coupled receptor, GPR54
    • DOI 10.1016/j.mce.2006.04.019, PII S0303720706002206
    • Pallais, J.C., Bo-Abbas, Y., Pitteloud, N., Crowley, W.F. and Seminara, S.B. (2006) Neuroendocrine, gonadal, placental, and obstetric phenotypes in patients with IHH and mutations in the G-protein coupled receptor, GPR54. Mol Cell Endocrinol 254:70-77. (Pubitemid 44041755)
    • (2006) Molecular and Cellular Endocrinology , vol.254-255 , pp. 70-77
    • Pallais, J.C.1    Bo-Abbas, Y.2    Pitteloud, N.3    Crowley Jr., W.F.4    Seminara, S.B.5
  • 49
    • 84872208198 scopus 로고    scopus 로고
    • The University of British Columbia. Thesis submitted for degree of PhD Vancouver. Website, June 2009
    • Pentice, L.M. (2009) The Kisspeptin and GPR54 ligand-receptor pair in autocrine and endocrine signalling in cancer. The University of British Columbia. Thesis submitted for degree of PhD Vancouver. Website: https://circle.ubc.ca/bitstream/handle/2429/ 10895/ubc-2009-fall-prentice-leah. pdf?sequence=1/ June 2009.
    • (2009) The Kisspeptin and GPR54 Ligand-receptor Pair in Autocrine and Endocrine Signalling in Cancer
    • Pentice, L.M.1
  • 50
    • 74949105195 scopus 로고    scopus 로고
    • Critical Roles of Kisspeptins in Female Puberty and Preovulatory Gonadotropin Surges as Revealed by a Novel Antagonist
    • Pineda, R., Garcia-Galiano, D., Roseweir, A., Romero, M., Sanchez-Garrido, M.A., Ruiz-Pino, F., et al. (2010) Critical Roles of Kisspeptins in Female Puberty and Preovulatory Gonadotropin Surges as Revealed by a Novel Antagonist. Endocrinology 151:722-730.
    • (2010) Endocrinology , vol.151 , pp. 722-730
    • Pineda, R.1    Garcia-Galiano, D.2    Roseweir, A.3    Romero, M.4    Sanchez-Garrido, M.A.5    Ruiz-Pino, F.6
  • 51
    • 0035066924 scopus 로고    scopus 로고
    • Neurobiological bases underlying the control of the onset of puberty in the rhesus monkey: A representative higher primate
    • DOI 10.1006/frne.2001.0211
    • Plant, T.M. (2001) Neurobiological bases underlying the control of the onset of puberty in the rhesus monkey: a representative higher primate. Front Neuroendocrinol 22:107-139. (Pubitemid 32281579)
    • (2001) Frontiers in Neuroendocrinology , vol.22 , Issue.2 , pp. 107-139
    • Plant, T.M.1
  • 52
    • 30944445420 scopus 로고    scopus 로고
    • Repetitive activation of hypothalamic G protein-coupled receptor 54 with intravenous pulses of kisspeptin in the juvenile monkey (Macaca mulatta) elicits a sustained train of gonadotropin-releasing hormone discharges
    • DOI 10.1210/en.2005-1261
    • Plant, T.M., Ramaswamy, S. and DiPietro, M.J. (2006) Repetitive activation of hypothalamic G protein-coupled receptor 54 with intravenous pulses of kisspeptin in the juvenile monkey (Macaca mulatta) elicits a sustained train of gonadotropin-releasing hormone discharges. Endocrinology 147:1007-1013. (Pubitemid 43113020)
    • (2006) Endocrinology , vol.147 , Issue.2 , pp. 1007-1013
    • Plant, T.M.1    Ramaswamy, S.2    DiPietro, M.J.3
  • 53
    • 34347252274 scopus 로고    scopus 로고
    • Effect of continuous intravenous administration of human metastin 45-54 on the neuroendocrine activity of the hypothalamic-pituitary-testicular axis in the adult male rhesus monkey (Macaca mulatta)
    • DOI 10.1210/en.2007-0207
    • Ramaswamy, S., Seminara, S.B., Pohl, C.R., DiPietro, M.J., Crowley,W. F. and Plant, T.M. (2007) Effect of continuous intravenous administration of human metastin 45-54 on the neuroendocrine activity of the hypothalamic-pituitary- testicular axis in the adult male rhesus monkey (Macaca mulatta). Endocrinology 148:3364-3370. (Pubitemid 46996993)
    • (2007) Endocrinology , vol.148 , Issue.7 , pp. 3364-3370
    • Ramaswamy, S.1    Seminara, S.B.2    Pohl, C.R.3    Dipietro, M.J.4    Crowley Jr., W.F.5    Plant, T.M.6
  • 54
    • 37649008207 scopus 로고    scopus 로고
    • New frontiers in kisspeptin/GPR54 physiology as fundamental gatekeepers of reproductive function
    • Roa, J., Aguilar, E., Dieguez, C., Pinilla, L. and Tena-Sempere, M. (2008a) New frontiers in kisspeptin/GPR54 physiology as fundamental gatekeepers of reproductive function. Front Neuroendocrinol 29:48-69.
    • (2008) Front Neuroendocrinol , vol.29 , pp. 48-69
    • Roa, J.1    Aguilar, E.2    Dieguez, C.3    Pinilla, L.4    Tena-Sempere, M.5
  • 55
    • 47549101608 scopus 로고    scopus 로고
    • Desensitization of gonadotropin responses to kisspeptin in the female rat: Analyses of LH and FSH secretion at different developmental and metabolic states
    • Roa, J., Vigo, E., Garcia-Galiano, D., Castellano, J.M., Navarro, V.M., Pineda, R., et al. (2008b) Desensitization of gonadotropin responses to kisspeptin in the female rat: analyses of LH and FSH secretion at different developmental and metabolic states. Am J Physiol Endocrinol Metab 294:E1088-E1096.
    • (2008) Am J Physiol Endocrinol Metab , vol.294
    • Roa, J.1    Vigo, E.2    Garcia-Galiano, D.3    Castellano, J.M.4    Navarro, V.M.5    Pineda, R.6
  • 56
    • 34447115135 scopus 로고    scopus 로고
    • Hypertrophy and increased kisspeptin gene expression in the hypothalamic infundibular nucleus of postmenopausal women and ovariectomized monkeys
    • DOI 10.1210/jc.2007-0553
    • Rometo, A.M., Krajewski, S.J., Voytko, M.L. and Rance, N.E. (2007) Hypertrophy and increased kisspeptin gene expression in the hypothalamic infundibular nucleus of postmenopausal women and ovariectomized monkeys. J Clin Endocrinol Metab 92:2744-2750. (Pubitemid 47037385)
    • (2007) Journal of Clinical Endocrinology and Metabolism , vol.92 , Issue.7 , pp. 2744-2750
    • Rometo, A.M.1    Krajewski, S.J.2    Voytko, M.L.3    Rance, N.E.4
  • 57
    • 64849108752 scopus 로고    scopus 로고
    • Discovery of potent kisspeptin antagonists delineate physiological mechanisms of gonadotropin regulation
    • Roseweir, A.K., Kauffman, A.S., Smith, J.T., Guerriero, K.A., Morgan, K., Pielecka-Fortuna, J., et al. (2009) Discovery of potent kisspeptin antagonists delineate physiological mechanisms of gonadotropin regulation. J Neurosci 29:3920-3929.
    • (2009) J Neurosci , vol.29 , pp. 3920-3929
    • Roseweir, A.K.1    Kauffman, A.S.2    Smith, J.T.3    Guerriero, K.A.4    Morgan, K.5    Pielecka-Fortuna, J.6
  • 62
    • 84861126333 scopus 로고    scopus 로고
    • ed. Shaw, R.W., Soutter, W.P., Stanton, S.L., Churchill Livingstone, Harcourt Publishers Ltd., Section one, Chapter 12
    • Shaw, R.W. (1999) Control of hypothalamic-pituitary ovarian function. Gynaecology, ed. Shaw, R.W., Soutter, W.P., Stanton, S.L., Churchill Livingstone, Harcourt Publishers Ltd., Section one, Chapter 12, pp. 171-183.
    • (1999) Control of Hypothalamic-pituitary Ovarian Function. Gynaecology , pp. 171-183
    • Shaw, R.W.1
  • 63
    • 77953880509 scopus 로고    scopus 로고
    • Genetics basis for GnRH-dependent pubertal disorders in humans
    • Silveira, L.F., Trarbach, E.B. and Latronico, A.C. (2010a) Genetics basis for GnRH-dependent pubertal disorders in humans. Mol Cell Endocrinol 324:30-38.
    • (2010) Mol Cell Endocrinol , vol.324 , pp. 30-38
    • Silveira, L.F.1    Trarbach, E.B.2    Latronico, A.C.3
  • 65
    • 23844435021 scopus 로고    scopus 로고
    • Regulation of Kiss1 gene expression in the brain of the female mouse
    • DOI 10.1210/en.2005-0488
    • Smith, J.T., Cunningham, M.J., Rissman, E.F., Clifton, D.K. and Steiner, R.A. (2005a) Regulation of Kiss1 gene expression in the brain of the female mouse. Endocrinology 146:3686-3692. (Pubitemid 41175732)
    • (2005) Endocrinology , vol.146 , Issue.9 , pp. 3686-3692
    • Smith, J.T.1    Cunningham, M.J.2    Rissman, E.F.3    Clifton, D.K.4    Steiner, R.A.5
  • 68
    • 33947493910 scopus 로고    scopus 로고
    • Neuroendocrine phenotype analysis in five patients with isolated hypogonadotropic hypogonadism due to a L102P inactivating mutation of GPR54
    • DOI 10.1210/jc.2006-2147
    • Tenenbaum-Rakover, Y., Commenges-Ducos, M., Iovane, A., Aumas, C., Admoni, O. and de Roux, N. (2007) Neuroendocrine phenotype analysis in five patients with isolated hypogonadotropic hypogonadism due to a L102P inactivating mutation of GPR54. J Clin Endocrinol Metab 92:1137-1144. (Pubitemid 46465693)
    • (2007) Journal of Clinical Endocrinology and Metabolism , vol.92 , Issue.3 , pp. 1137-1144
    • Tenenbaum-Rakover, Y.1    Commenges-Ducos, M.2    Iovane, A.3    Aumas, C.4    Admoni, O.5    De Roux, N.6
  • 69
    • 0032533648 scopus 로고    scopus 로고
    • Chromosome localization and genomic structure of the KiSS-1 metastasis suppressor gene (KISS1)
    • DOI 10.1006/geno.1998.5566
    • West, A., Vojta, P.J.,Welch, D.R. andWeissman, B.E. (1998) Chromosome localization and genomic structure of the KiSS-1 metastasis suppressor gene (KISS1). Genomics 54:145-148. (Pubitemid 28536204)
    • (1998) Genomics , vol.54 , Issue.1 , pp. 145-148
    • West, A.1    Vojta, P.J.2    Welch, D.R.3    Weissman, B.E.4


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