Inhibition of thrombin-induced Ca 2+ influx in platelets by R59949, an inhibitor of diacylglycerol kinase

Journal of Pharmacy and Pharmacology

Volumn 64, Issue 6, 2012, Pages 855-861

  Marumo, Mikio ^a   Nakano, Tomoyuki ^a   Takeda, Yuji ^a   Goto, Kaoru ^b   Wakabayashi, Ichiro ^a  

^a HYOGO COLLEGE OF MEDICINE   (Japan)

^b YAMAGATA UNIVERSITY   (Japan)

Author keywords

Ca 2+ entry; diacylglycerol kinase; phosphatidic acid; platelet; R59949

Indexed keywords

1 [2 (4 METHOXYPHENYL) 2 [3 (4 METHOXYPHENYL)PROPOXY]ETHYL] 1H IMIDAZOLE; 3 [2 [4 (4,4' DIFLUOROBENZHYDRYLIDENE)PIPERIDINO]ETHYL] 2,3 DIHYDRO 2 THIOXO 4(1H) QUINAZOLINONE; BUTANOL; CALCIUM ION; DIACYLGLYCEROL KINASE; DIACYLGLYCEROL KINASE ALPHA; DIACYLGLYCEROL KINASE BETA; DIACYLGLYCEROL KINASE DELTA; DIACYLGLYCEROL KINASE EPSILON; DIACYLGLYCEROL KINASE ETA; DIACYLGLYCEROL KINASE GAMMA; DIACYLGLYCEROL KINASE IOTA; DIACYLGLYCEROL KINASE THETA; DIACYLGLYCEROL KINASE ZETA; MESSENGER RNA; PROPRANOLOL; THAPSIGARGIN; THROMBIN; UNCLASSIFIED DRUG;

ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CONTROLLED STUDY; DRUG EFFECT; HUMAN; HUMAN CELL; INHIBITION KINETICS; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; THROMBOCYTE;

BLOOD PLATELETS; BUTANOLS; CALCIUM; CALCIUM CHANNEL BLOCKERS; CELL MEMBRANE; DIACYLGLYCEROL KINASE; HEMOSTATICS; HUMANS; IMIDAZOLES; PHOSPHATIDIC ACIDS; PIPERIDINES; PLANT EXTRACTS; PLATELET AGGREGATION; PROPRANOLOL; QUINAZOLINONES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; THAPSIA; THAPSIGARGIN; THROMBIN;

EID: 84861098068     PISSN: 00223573     EISSN: 20427158     Source Type: Journal    
DOI: 10.1111/j.2042-7158.2012.01485.x     Document Type: Article

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