Mesenchymal stem cells from primary breast cancer tissue promote cancer proliferation and enhance mammosphere formation partially via EGF/EGFR/Akt pathway

Breast Cancer Research and Treatment

Volumn 132, Issue 1, 2012, Pages 153-164

  Yan, Xin Long ^a   Fu, Chun Jiang ^a,b   Chen, Lin ^a   Qin, Jin Hua ^a   Zeng, Quan ^a   Yuan, Hong Feng ^a   Nan, Xue ^a   Chen, Hai Xu ^a   Zhou, Jun Nian ^a   Lin, Yan Li ^c   Zhang, Xiao Mei ^a   Yu, Cheng Ze ^a   Yue, Wen ^a   Pei, Xue Tao ^a  

^a BEIJING INSTITUTE OF MICROBIOLOGY AND EPIDEMIOLOGY   (China)

^b Beijing Fangshan Traditional Chinese Medicine Hospital   (China)

^c BEIJING INSTITUTE OF BIOTECHNOLOGY   (China)

Author keywords

Breast cancer; EGF; Mammosphere; Mesenchymal stem cells; PI3K Akt; Proliferation; Xenograft

Indexed keywords

EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B;

ADIPOCYTE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREAST CANCER; CANCER GROWTH; CANCER STEM CELL; CANCER TISSUE; CARTILAGE CELL; CELL DIFFERENTIATION; CELL ISOLATION; CELL LINEAGE; CELL PROLIFERATION; CELL STRUCTURE; CELLULAR PARAMETERS; COCULTURE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; IMMUNOPHENOTYPING; IN VIVO STUDY; MAMMOSPHERE FORMATION; MESENCHYMAL STEM CELL; MESENCHYMAL STEM CELL TRANSPLANTATION; MOLECULAR INTERACTION; MOUSE; NONHUMAN; OSTEOBLAST; PRIMARY TUMOR; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN SECRETION; SIGNAL TRANSDUCTION; TUMOR MICROENVIRONMENT; TUMOR VOLUME; TUMOR XENOGRAFT;

ANIMALS; ANTIGENS, DIFFERENTIATION; BREAST NEOPLASMS; CARCINOMA, DUCTAL, BREAST; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SHAPE; COCULTURE TECHNIQUES; EPIDERMAL GROWTH FACTOR; FEMALE; HUMANS; MESENCHYMAL STEM CELLS; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; NEOPLASTIC STEM CELLS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION; SPHEROIDS, CELLULAR; TUMOR BURDEN; TUMOR CELLS, CULTURED;

EID: 84857915804     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-011-1577-0     Document Type: Article

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