Head-to-head prenyl tranferases: Anti-infective drug targets

Journal of Medicinal Chemistry

Volumn 55, Issue 9, 2012, Pages 4367-4372

  Lin, Fu Yang ^a   Liu, Yi Liang ^a   Li, Kai ^b   Cao, Rong ^a   Zhu, Wei ^a   Axelson, Jordan ^b   Pang, Ran ^c   Oldfield, Eric ^a,b  

^a Center for Biophysics and Computational Biology   (United States)

^b Department of Chemistry ^*  (United States)

^c UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAMANTANE; ANTIINFECTIVE AGENT; BPH 651; CATION; DIMETHYLALLYLTRANSFERASE; N (2 ADAMANTYL) N' GERANYLETHYLENEDIAMINE; SQUALENE SYNTHASE INHIBITOR; UNCLASSIFIED DRUG; WC 9;

ARTICLE; BINDING SITE; CYCLOADDITION; DRUG DESIGN; DRUG TARGETING; HYDROGEN BOND; IONIZATION; MOLECULAR INTERACTION; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PURIFICATION; PROTEIN SECONDARY STRUCTURE; STAPHYLOCOCCUS AUREUS; STRUCTURE ACTIVITY RELATION; X RAY CRYSTALLOGRAPHY;

ADAMANTANE; BACTERIAL PROTEINS; CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; ETHYLENEDIAMINES; FARNESYL-DIPHOSPHATE FARNESYLTRANSFERASE; MODELS, MOLECULAR; PHENYL ETHERS; QUINUCLIDINES; STAPHYLOCOCCUS AUREUS; THIOCYANATES;

EID: 84861089202     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm300208p     Document Type: Article

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