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Volumn 590, Issue 10, 2012, Pages 2333-2351

Lactate flux in astrocytes is enhanced by a non-catalytic action of carbonic anhydrase II

Author keywords

[No Author keywords available]

Indexed keywords

CARBONATE DEHYDRATASE II; CARBOXY TERMINAL TELOPEPTIDE; LACTIC ACID; MONOCARBOXYLATE TRANSPORTER 1;

EID: 84861012031     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2011.220152     Document Type: Article
Times cited : (60)

References (80)
  • 1
    • 1942440463 scopus 로고    scopus 로고
    • Surface-mediated proton-transfer reactions in membrane-bound proteins
    • Ädelroth P & Brzezinski P (2004). Surface-mediated proton-transfer reactions in membrane-bound proteins. Biochim Biophys Acta 1655, 102-115.
    • (2004) Biochim Biophys Acta , vol.1655 , pp. 102-115
    • Ädelroth, P.1    Brzezinski, P.2
  • 2
    • 84897726517 scopus 로고
    • Carbonic anhydrase activity associated with the cyanobacterium Synechococcus PCC7942
    • Badger MR & Price GD (1989). Carbonic anhydrase activity associated with the cyanobacterium Synechococcus PCC7942. Plant Physiol 89, 51-60.
    • (1989) Plant Physiol , vol.89 , pp. 51-60
    • Badger, M.R.1    Price, G.D.2
  • 3
    • 0346688718 scopus 로고    scopus 로고
    • Facilitated lactate transport by MCT1 when coexpressed with the sodium bicarbonate cotransporter (NBC) in Xenopus oocytes
    • Becker HM, Bröer S & Deitmer JW (2004). Facilitated lactate transport by MCT1 when coexpressed with the sodium bicarbonate cotransporter (NBC) in Xenopus oocytes. Biophys J 86, 235-247.
    • (2004) Biophys J , vol.86 , pp. 235-247
    • Becker, H.M.1    Bröer, S.2    Deitmer, J.W.3
  • 5
    • 52049118802 scopus 로고    scopus 로고
    • +-lactate cotransport via monocarboxylate transporter 1
    • +-lactate cotransport via monocarboxylate transporter 1. J Biol Chem 283, 21655-21667.
    • (2008) J Biol Chem , vol.283 , pp. 21655-21667
    • Becker, H.M.1    Deitmer, J.W.2
  • 6
    • 28844503376 scopus 로고    scopus 로고
    • Transport activity of MCT1 expressed in Xenopus oocytes is increased by interaction with carbonic anhydrase
    • Becker HM, Fecher-Trost C, Hirnet D, Sültemeyer D & Deitmer JW (2005). Transport activity of MCT1 expressed in Xenopus oocytes is increased by interaction with carbonic anhydrase. J Biol Chem 280, 39882-39889.
    • (2005) J Biol Chem , vol.280 , pp. 39882-39889
    • Becker, H.M.1    Fecher-Trost, C.2    Hirnet, D.3    Sültemeyer, D.4    Deitmer, J.W.5
  • 7
    • 77952214629 scopus 로고    scopus 로고
    • Nonenzymatic augmentation of lactate transport via monocarboxylate transporter isoform 4 by carbonic anhydrase II
    • Becker HM, Klier M & Deitmer JW (2010). Nonenzymatic augmentation of lactate transport via monocarboxylate transporter isoform 4 by carbonic anhydrase II. J Membr Biol 234, 125-135.
    • (2010) J Membr Biol , vol.234 , pp. 125-135
    • Becker, H.M.1    Klier, M.2    Deitmer, J.W.3
  • 8
    • 79952584606 scopus 로고    scopus 로고
    • Intramolecular proton shuttle supports not only catalytic but also noncatalytic function of carbonic anhydrase II
    • Becker HM, Klier M, Schüler C, McKenna R & Deitmer JW (2011). Intramolecular proton shuttle supports not only catalytic but also noncatalytic function of carbonic anhydrase II. Proc Natl Acad Sci U S A 108, 3071-3076.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 3071-3076
    • Becker, H.M.1    Klier, M.2    Schüler, C.3    McKenna, R.4    Deitmer, J.W.5
  • 9
    • 0036130456 scopus 로고    scopus 로고
    • Immunogold cytochemistry identifies specialized membrane domains for monocarboxylate transport in the central nervous system
    • Bergersen L, Rafiki A & Ottersen OP (2002). Immunogold cytochemistry identifies specialized membrane domains for monocarboxylate transport in the central nervous system. Neurochem Res 27, 89-96.
    • (2002) Neurochem Res , vol.27 , pp. 89-96
    • Bergersen, L.1    Rafiki, A.2    Ottersen, O.P.3
  • 13
    • 33845936297 scopus 로고    scopus 로고
    • Localized proton microcircuits at the biological membrane-water interface
    • Bränden M, Sanden T, Brzezinski P & Widengren J (2006). Localized proton microcircuits at the biological membrane-water interface. Proc Natl Acad Sci U S A 103, 19766-19770.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 19766-19770
    • Bränden, M.1    Sanden, T.2    Brzezinski, P.3    Widengren, J.4
  • 14
    • 0030774069 scopus 로고    scopus 로고
    • Comparison of lactate transport in astroglial cells and monocarboxylate transporter 1 (MCT 1) expressing Xenopus laevis oocytes. Expression of two different monocarboxylate transporters in astroglial cells and neurons
    • Bröer S, Rahman B, Pellegri G, Pellerin L, Martin JL, Verleysdonk S, Hamprecht B & Magistretti PJ (1997). Comparison of lactate transport in astroglial cells and monocarboxylate transporter 1 (MCT 1) expressing Xenopus laevis oocytes. Expression of two different monocarboxylate transporters in astroglial cells and neurons. J Biol Chem 272, 30096-30102.
    • (1997) J Biol Chem , vol.272 , pp. 30096-30102
    • Bröer, S.1    Rahman, B.2    Pellegri, G.3    Pellerin, L.4    Martin, J.L.5    Verleysdonk, S.6    Hamprecht, B.7    Magistretti, P.J.8
  • 15
    • 0032127127 scopus 로고    scopus 로고
    • Characterization of the monocarboxylate transporter 1 expressed in Xenopus laevis oocytes by changes in cytosolic pH
    • Bröer S, Schneider HP, Bröer A, Rahman B, Hamprecht B & Deitmer JW (1998). Characterization of the monocarboxylate transporter 1 expressed in Xenopus laevis oocytes by changes in cytosolic pH. Biochem J 333, 167-174.
    • (1998) Biochem J , vol.333 , pp. 167-174
    • Bröer, S.1    Schneider, H.P.2    Bröer, A.3    Rahman, B.4    Hamprecht, B.5    Deitmer, J.W.6
  • 17
    • 0028605480 scopus 로고
    • The kinetics, substrate and inhibitor specificity of the lactate transporter of Ehrlich-Lettre tumour cells studied with the intracellular pH indicator BCECF
    • Carpenter L & Halestrap AP (1994). The kinetics, substrate and inhibitor specificity of the lactate transporter of Ehrlich-Lettre tumour cells studied with the intracellular pH indicator BCECF. Biochem J 304, 751-760.
    • (1994) Biochem J , vol.304 , pp. 751-760
    • Carpenter, L.1    Halestrap, A.P.2
  • 18
    • 0020074781 scopus 로고
    • Developmental modulations of blood-brain barrier permeability as an indicator of changing nutritional requirements in the brain
    • Cornford EM, Braun LD & Oldendorf WH (1982). Developmental modulations of blood-brain barrier permeability as an indicator of changing nutritional requirements in the brain. Pediatr Res 16, 324-328.
    • (1982) Pediatr Res , vol.16 , pp. 324-328
    • Cornford, E.M.1    Braun, L.D.2    Oldendorf, W.H.3
  • 19
    • 0842322960 scopus 로고    scopus 로고
    • A reduced cerebral metabolic ratio in exercise reflects metabolism and not accumulation of lactate within the human brain
    • Dalsgaard MK, Quistorff B, Danielsen ER, Selmer C, Vogelsang T & Secher NH (2004). A reduced cerebral metabolic ratio in exercise reflects metabolism and not accumulation of lactate within the human brain. J Physiol 554, 571-578.
    • (2004) J Physiol , vol.554 , pp. 571-578
    • Dalsgaard, M.K.1    Quistorff, B.2    Danielsen, E.R.3    Selmer, C.4    Vogelsang, T.5    Secher, N.H.6
  • 20
    • 0020956323 scopus 로고
    • Kinetic analysis of L-lactate transport in human erythrocytes via the monocarboxylate-specific carrier system
    • De Bruijne AW, Vreeburg H & Van Steveninck J (1983). Kinetic analysis of L-lactate transport in human erythrocytes via the monocarboxylate-specific carrier system. Biochim Biophys Acta 732, 562-568.
    • (1983) Biochim Biophys Acta , vol.732 , pp. 562-568
    • De Bruijne, A.W.1    Vreeburg, H.2    Van Steveninck, J.3
  • 21
    • 0037963512 scopus 로고    scopus 로고
    • Cell-specific expression pattern of monocarboxylate transporters in astrocytes and neurons observed in different mouse brain cortical cell cultures
    • Debernardi R, Pierre K, Lengacher S, Magistretti PJ & Pellerin L (2003). Cell-specific expression pattern of monocarboxylate transporters in astrocytes and neurons observed in different mouse brain cortical cell cultures. J Neurosci Res 73, 141-155.
    • (2003) J Neurosci Res , vol.73 , pp. 141-155
    • Debernardi, R.1    Pierre, K.2    Lengacher, S.3    Magistretti, P.J.4    Pellerin, L.5
  • 22
    • 0026055861 scopus 로고
    • Electrogenic sodium-dependent bicarbonate secretion by glial cells of the leech central nervous system
    • Deitmer JW (1991). Electrogenic sodium-dependent bicarbonate secretion by glial cells of the leech central nervous system. J Gen Physiol 98, 637-655.
    • (1991) J Gen Physiol , vol.98 , pp. 637-655
    • Deitmer, J.W.1
  • 23
    • 0035178222 scopus 로고    scopus 로고
    • Strategies for metabolic exchange between glial cells and neurons
    • Deitmer JW (2001). Strategies for metabolic exchange between glial cells and neurons. Respir Physiol 129, 71-81.
    • (2001) Respir Physiol , vol.129 , pp. 71-81
    • Deitmer, J.W.1
  • 24
    • 0025055719 scopus 로고
    • Membrane potential dependence of intracellular pH regulation by identified glial cells in the leech central nervous system
    • Deitmer JW & Szatkowski M (1990). Membrane potential dependence of intracellular pH regulation by identified glial cells in the leech central nervous system. J Physiol 421, 617-631.
    • (1990) J Physiol , vol.421 , pp. 617-631
    • Deitmer, J.W.1    Szatkowski, M.2
  • 25
    • 0024376664 scopus 로고
    • Lactate, 3-hydroxybutyrate, and glucose as substrates for the early postnatal rat brain
    • Dombrowski GJJ, Swiatek KR & Chao KL (1989). Lactate, 3-hydroxybutyrate, and glucose as substrates for the early postnatal rat brain. Neurochem Res 14, 667-675.
    • (1989) Neurochem Res , vol.14 , pp. 667-675
    • Dombrowski, G.J.J.1    Swiatek, K.R.2    Chao, K.L.3
  • 26
    • 0027604406 scopus 로고
    • Incorporation of radioactivity from [14C]lactate into the glycogen of cultured mouse astroglial cells. Evidence for gluconeogenesis in brain cells
    • Dringen R, Schmoll D, Cesar M & Hamprecht B (1993). Incorporation of radioactivity from [14C]lactate into the glycogen of cultured mouse astroglial cells. Evidence for gluconeogenesis in brain cells. Biol Chem Hoppe Seyler 374, 343-347.
    • (1993) Biol Chem Hoppe Seyler , vol.374 , pp. 343-347
    • Dringen, R.1    Schmoll, D.2    Cesar, M.3    Hamprecht, B.4
  • 27
    • 60349123753 scopus 로고    scopus 로고
    • Reporting ethical matters in The Journal of Physiology: standards and advice
    • Drummond GB (2009). Reporting ethical matters in The Journal of Physiology: standards and advice. J Physiol 15, 713-719.
    • (2009) J Physiol , vol.15 , pp. 713-719
    • Drummond, G.B.1
  • 28
    • 0024326213 scopus 로고
    • A thin slice preparation for patch clamp recordings from neurones of the mammalian central nervous system
    • Edwards FA, Konnerth A, Sakmann B & Takahashi T (1989). A thin slice preparation for patch clamp recordings from neurones of the mammalian central nervous system. Pflugers Arch 414, 600-612.
    • (1989) Pflugers Arch , vol.414 , pp. 600-612
    • Edwards, F.A.1    Konnerth, A.2    Sakmann, B.3    Takahashi, T.4
  • 29
    • 13244281317 scopus 로고    scopus 로고
    • Coot: model-building tools for molecular graphics
    • Emsley P & Cowtan K (2004). Coot: model-building tools for molecular graphics. Acta Cryst 60, 2126-2132.
    • (2004) Acta Cryst , vol.60 , pp. 2126-2132
    • Emsley, P.1    Cowtan, K.2
  • 30
    • 44949166565 scopus 로고    scopus 로고
    • Inhibition of monocarboxylate transporter 2 in the retrotrapezoid nucleus in rats: a test of the astrocyte-neuron lactate-shuttle hypothesis
    • Erlichman JS, Hewitt A, Damon TL, Hart M, Kurascz J, Li A & Leiter JC (2008). Inhibition of monocarboxylate transporter 2 in the retrotrapezoid nucleus in rats: a test of the astrocyte-neuron lactate-shuttle hypothesis. J Neurosci 28, 4888-4896.
    • (2008) J Neurosci , vol.28 , pp. 4888-4896
    • Erlichman, J.S.1    Hewitt, A.2    Damon, T.L.3    Hart, M.4    Kurascz, J.5    Li, A.6    Leiter, J.C.7
  • 31
    • 0020477932 scopus 로고
    • Lactate as energy source for brain in glucose-6-phosphatase deficient child
    • Fernandes J, Berger R & Smit GP (1982). Lactate as energy source for brain in glucose-6-phosphatase deficient child. Lancet 1, 113.
    • (1982) Lancet , vol.1 , pp. 113
    • Fernandes, J.1    Berger, R.2    Smit, G.P.3
  • 33
    • 0029857160 scopus 로고    scopus 로고
    • The mechanisms controlling physiologically stimulated changes in rat brain glucose and lactate: a microdialysis study
    • Fray AE, Forsyth RJ, Boutelle MG & Fillenz M (1996). The mechanisms controlling physiologically stimulated changes in rat brain glucose and lactate: a microdialysis study. J Physiol 496, 49-57.
    • (1996) J Physiol , vol.496 , pp. 49-57
    • Fray, A.E.1    Forsyth, R.J.2    Boutelle, M.G.3    Fillenz, M.4
  • 34
    • 0347517756 scopus 로고    scopus 로고
    • The loop between helix 4 and helix 5 in the monocarboxylate transporter MCT1 is important for substrate selection and protein stability
    • Galic S, Schneider HP, Bröer A, Deitmer JW & Bröer S (2003). The loop between helix 4 and helix 5 in the monocarboxylate transporter MCT1 is important for substrate selection and protein stability. Biochem J 376, 413-422.
    • (2003) Biochem J , vol.376 , pp. 413-422
    • Galic, S.1    Schneider, H.P.2    Bröer, A.3    Deitmer, J.W.4    Bröer, S.5
  • 35
    • 0030837750 scopus 로고    scopus 로고
    • Expression of monocarboxylate transporter MCT1 by brain endothelium and glia in adult and suckling rats
    • Gerhart DZ, Enerson BE, Zhdankina OY, Leino RL & Drewes LR (1997). Expression of monocarboxylate transporter MCT1 by brain endothelium and glia in adult and suckling rats. Am J Physiol 273, 207-213.
    • (1997) Am J Physiol , vol.273 , pp. 207-213
    • Gerhart, D.Z.1    Enerson, B.E.2    Zhdankina, O.Y.3    Leino, R.L.4    Drewes, L.R.5
  • 37
    • 0019485423 scopus 로고
    • Glial cell markers in the reeler mutant mouse: a biochemical and immunohistological study
    • Ghandour MS, Derer P, Labourdette G, Delaunoy JP & Langley OK (1981). Glial cell markers in the reeler mutant mouse: a biochemical and immunohistological study. J Neurochem 36, 195-200.
    • (1981) J Neurochem , vol.36 , pp. 195-200
    • Ghandour, M.S.1    Derer, P.2    Labourdette, G.3    Delaunoy, J.P.4    Langley, O.K.5
  • 38
    • 0016596344 scopus 로고
    • Induction processes in blood-brain transfer of ketone bodies during starvation
    • Gjedde A & Crone C (1975). Induction processes in blood-brain transfer of ketone bodies during starvation. Am J Physiol 229, 1165-1169.
    • (1975) Am J Physiol , vol.229 , pp. 1165-1169
    • Gjedde, A.1    Crone, C.2
  • 39
    • 0028077918 scopus 로고
    • Depolarization-induced acid secretion in gliotic hippocampal slices
    • Grichtchenko II & Chesler M (1994). Depolarization-induced acid secretion in gliotic hippocampal slices. Neuroscience 62, 1057-1070.
    • (1994) Neuroscience , vol.62 , pp. 1057-1070
    • Grichtchenko, I.I.1    Chesler, M.2
  • 40
    • 33745092120 scopus 로고    scopus 로고
    • The dynamics of proton transfer between adjacent sites
    • Gutman M, Nachliel E & Friedman R (2006). The dynamics of proton transfer between adjacent sites. Photochem Photobiol Sci 5, 531-537.
    • (2006) Photochem Photobiol Sci , vol.5 , pp. 531-537
    • Gutman, M.1    Nachliel, E.2    Friedman, R.3
  • 41
    • 0033569442 scopus 로고    scopus 로고
    • The proton-linked monocarboxylate transporter (MCT) family: structure, function and regulation
    • Halestrap AP & Price NT (1999). The proton-linked monocarboxylate transporter (MCT) family: structure, function and regulation. Biochem J 343, 281-299.
    • (1999) Biochem J , vol.343 , pp. 281-299
    • Halestrap, A.P.1    Price, N.T.2
  • 42
    • 0022552442 scopus 로고
    • Regional ketone body utilization by rat brain in starvation and diabetes
    • Hawkins RA, Mans AM & Davis DW (1986). Regional ketone body utilization by rat brain in starvation and diabetes. Am J Physiol 250, 169-178.
    • (1986) Am J Physiol , vol.250 , pp. 169-178
    • Hawkins, R.A.1    Mans, A.M.2    Davis, D.W.3
  • 43
    • 0015020675 scopus 로고
    • Ketone-body utilization by adult and suckling rat brain in vivo
    • Hawkins RA, Williamson DH & Krebs HA (1971). Ketone-body utilization by adult and suckling rat brain in vivo. Biochem J 122, 13-18.
    • (1971) Biochem J , vol.122 , pp. 13-18
    • Hawkins, R.A.1    Williamson, D.H.2    Krebs, H.A.3
  • 44
    • 79961016325 scopus 로고    scopus 로고
    • Transport activity of the high-affinity monocarboxylate transporter MCT2 is enhanced by extracellular carbonic anhydrase IV but not by intracellular carbonic anhydrase II
    • Klier M, Schüler C, Halestrap AP, Sly WS, Deitmer JW & Becker HM (2011). Transport activity of the high-affinity monocarboxylate transporter MCT2 is enhanced by extracellular carbonic anhydrase IV but not by intracellular carbonic anhydrase II. J Biol Chem 286, 27781-27791.
    • (2011) J Biol Chem , vol.286 , pp. 27781-27791
    • Klier, M.1    Schüler, C.2    Halestrap, A.P.3    Sly, W.S.4    Deitmer, J.W.5    Becker, H.M.6
  • 45
    • 20444482538 scopus 로고    scopus 로고
    • A procedure for culturing astrocytes from white matter and the application of the siRNA technique for silencing the expression of their specific marker, S100A4
    • Kozlova EN & Takenaga K (2005). A procedure for culturing astrocytes from white matter and the application of the siRNA technique for silencing the expression of their specific marker, S100A4. Brain Res Brain Res Protoc 15, 59-65.
    • (2005) Brain Res Brain Res Protoc , vol.15 , pp. 59-65
    • Kozlova, E.N.1    Takenaga, K.2
  • 46
    • 0024121523 scopus 로고
    • N-ethyl-N-nitrosourea-induced null mutation at the mouse Car-2 locus: an animal model for human carbonic anhydrase II deficiency syndrome
    • Lewis SE, Erickson RP, Barnett LB, Venta PJ & Tashian RE (1988). N-ethyl-N-nitrosourea-induced null mutation at the mouse Car-2 locus: an animal model for human carbonic anhydrase II deficiency syndrome. Proc Natl Acad Sci U S A 85, 1962-1966.
    • (1988) Proc Natl Acad Sci U S A , vol.85 , pp. 1962-1966
    • Lewis, S.E.1    Erickson, R.P.2    Barnett, L.B.3    Venta, P.J.4    Tashian, R.E.5
  • 50
    • 0027763898 scopus 로고
    • Neurotransmitters regulate energy metabolism in astrocytes: implications for the metabolic trafficking between neural cells
    • Magistretti PJ, Sorg O, Yu N, Martin JL & Pellerin L (1993). Neurotransmitters regulate energy metabolism in astrocytes: implications for the metabolic trafficking between neural cells. Dev Neurosci 15, 306-312.
    • (1993) Dev Neurosci , vol.15 , pp. 306-312
    • Magistretti, P.J.1    Sorg, O.2    Yu, N.3    Martin, J.L.4    Pellerin, L.5
  • 53
    • 78650764923 scopus 로고    scopus 로고
    • Food for thought: the importance of glucose and other energy substrates for sustaining brain function under varying levels of activity
    • Pellerin L (2010). Food for thought: the importance of glucose and other energy substrates for sustaining brain function under varying levels of activity. Diabetes Metab 36, 59-63.
    • (2010) Diabetes Metab , vol.36 , pp. 59-63
    • Pellerin, L.1
  • 55
    • 0036254152 scopus 로고    scopus 로고
    • MCT2 is a major neuronal monocarboxylate transporter in the adult mouse brain
    • Pierre K, Magistretti PJ & Pellerin L (2002). MCT2 is a major neuronal monocarboxylate transporter in the adult mouse brain. J Cereb Blood Flow Metab 22, 586-595.
    • (2002) J Cereb Blood Flow Metab , vol.22 , pp. 586-595
    • Pierre, K.1    Magistretti, P.J.2    Pellerin, L.3
  • 56
    • 21344444566 scopus 로고    scopus 로고
    • Monocarboxylate transporters in the central nervous system: distribution, regulation and function
    • Pierre K & Pellerin L (2005). Monocarboxylate transporters in the central nervous system: distribution, regulation and function. J Neurochem 94, 1-14.
    • (2005) J Neurochem , vol.94 , pp. 1-14
    • Pierre, K.1    Pellerin, L.2
  • 58
    • 0242485280 scopus 로고    scopus 로고
    • Highly differential expression of the monocarboxylate transporters MCT2 and MCT4 in the developing rat brain
    • Rafiki A, Boulland JL, Halestrap AP, Ottersen OP & Bergersen L (2003). Highly differential expression of the monocarboxylate transporters MCT2 and MCT4 in the developing rat brain. Neuroscience 122, 677-688.
    • (2003) Neuroscience , vol.122 , pp. 677-688
    • Rafiki, A.1    Boulland, J.L.2    Halestrap, A.P.3    Ottersen, O.P.4    Bergersen, L.5
  • 59
    • 0033621031 scopus 로고    scopus 로고
    • Helix 8 and helix 10 are involved in substrate recognition in the rat monocarboxylate transporter MCT1
    • Rahman B, Schneider HP, Bröer A, Deitmer JW & Bröer S (1999). Helix 8 and helix 10 are involved in substrate recognition in the rat monocarboxylate transporter MCT1. Biochemistry 38, 11577-11584.
    • (1999) Biochemistry , vol.38 , pp. 11577-11584
    • Rahman, B.1    Schneider, H.P.2    Bröer, A.3    Deitmer, J.W.4    Bröer, S.5
  • 60
    • 0027974233 scopus 로고
    • Evidence that glial cells modulate extracellular pH transients induced by neuronal activity in the leech central nervous system
    • Rose CR & Deitmer JW (1994). Evidence that glial cells modulate extracellular pH transients induced by neuronal activity in the leech central nervous system. J Physiol 481, 1-5.
    • (1994) J Physiol , vol.481 , pp. 1-5
    • Rose, C.R.1    Deitmer, J.W.2
  • 61
    • 0028887449 scopus 로고
    • Stimulus-evoked changes of extra- and intracellular pH in the leech central nervous system. I
    • Rose CR & Deitmer JW (1995). Stimulus-evoked changes of extra- and intracellular pH in the leech central nervous system. I. J Neurophysiol 73, 125-131.
    • (1995) J Neurophysiol , vol.73 , pp. 125-131
    • Rose, C.R.1    Deitmer, J.W.2
  • 62
    • 0020346412 scopus 로고
    • Carbonic anhydrase: oxygen-18 exchange catalyzed by an enzyme with rate-contributing proton-transfer steps
    • Silverman DN (1982). Carbonic anhydrase: oxygen-18 exchange catalyzed by an enzyme with rate-contributing proton-transfer steps. Methods Enzymol 87, 732-752.
    • (1982) Methods Enzymol , vol.87 , pp. 732-752
    • Silverman, D.N.1
  • 63
    • 34547624611 scopus 로고    scopus 로고
    • Supply and demand in cerebral energy metabolism: the role of nutrient transporters
    • Simpson IA, Carruthers A & Vannucci SJ (2007). Supply and demand in cerebral energy metabolism: the role of nutrient transporters. J Cereb Blood Flow Metab 27, 1766-1791.
    • (2007) J Cereb Blood Flow Metab , vol.27 , pp. 1766-1791
    • Simpson, I.A.1    Carruthers, A.2    Vannucci, S.J.3
  • 66
    • 84889385876 scopus 로고    scopus 로고
    • Carbonic anhydrases as drug targets: general presentation
    • ed. Supuran CT & Winum J-Y. John Wiley & Sons, Inc., New Jersey.
    • Supuran CT (2009). Carbonic anhydrases as drug targets: general presentation. In Drug Design of Zinc-Enzyme Inhibitors, ed. Supuran CT & Winum J-Y, pp. 15-17. John Wiley & Sons, Inc., New Jersey.
    • (2009) Drug Design of Zinc-Enzyme Inhibitors , pp. 15-17
    • Supuran, C.T.1
  • 68
    • 0037337552 scopus 로고    scopus 로고
    • Surface carbonic anhydrase activity on astrocytes and neurons facilitates lactate transport
    • Svichar N & Chesler M (2003). Surface carbonic anhydrase activity on astrocytes and neurons facilitates lactate transport. Glia 41, 415-419.
    • (2003) Glia , vol.41 , pp. 415-419
    • Svichar, N.1    Chesler, M.2
  • 69
    • 32344442199 scopus 로고    scopus 로고
    • Functional demonstration of surface carbonic anhydrase IV activity on rat astrocytes
    • Svichar N, Esquenazi S, Waheed A, Sly WS & Chesler M (2006). Functional demonstration of surface carbonic anhydrase IV activity on rat astrocytes. Glia 53, 241-247.
    • (2006) Glia , vol.53 , pp. 241-247
    • Svichar, N.1    Esquenazi, S.2    Waheed, A.3    Sly, W.S.4    Chesler, M.5
  • 70
    • 0033855459 scopus 로고    scopus 로고
    • Activity-dependent pH shifts in hippocampal slices from normal and carbonic anhydrase II-deficient mice
    • Tong CK, Cammer W & Chesler M (2000). Activity-dependent pH shifts in hippocampal slices from normal and carbonic anhydrase II-deficient mice. Glia 31, 25-30.
    • (2000) Glia , vol.31 , pp. 25-30
    • Tong, C.K.1    Cammer, W.2    Chesler, M.3
  • 71
    • 0037240512 scopus 로고    scopus 로고
    • Ischemia-induced changes in monocarboxylate transporter 1 reactive cells in rat hippocampus
    • Tseng MT, Chan SA & Schurr A (2003). Ischemia-induced changes in monocarboxylate transporter 1 reactive cells in rat hippocampus. Neurol Res 25, 83-86.
    • (2003) Neurol Res , vol.25 , pp. 83-86
    • Tseng, M.T.1    Chan, S.A.2    Schurr, A.3
  • 72
    • 0024421430 scopus 로고
    • Role of histidine 64 in the catalytic mechanism of human carbonic anhydrase II studied with a site-specific mutant
    • Tu CK, Silverman DN, Forsman C & Jonsson, BH (1989). Role of histidine 64 in the catalytic mechanism of human carbonic anhydrase II studied with a site-specific mutant. Biochemistry 28, 7913-7918.
    • (1989) Biochemistry , vol.28 , pp. 7913-7918
    • Tu, C.K.1    Silverman, D.N.2    Forsman, C.3    Jonsson, B.H.4
  • 75
    • 0023833266 scopus 로고
    • Lactate production and release in cultured astrocytes
    • Walz W & Mukerji S (1988). Lactate production and release in cultured astrocytes. Neurosci Lett 86, 296-300.
    • (1988) Neurosci Lett , vol.86 , pp. 296-300
    • Walz, W.1    Mukerji, S.2
  • 76
    • 0842344387 scopus 로고    scopus 로고
    • Astrocytes and synaptosomes transport and metabolize lactate and acetate differently
    • Waniewski RA & Martin DL (2004). Astrocytes and synaptosomes transport and metabolize lactate and acetate differently. Neurochem Res 29, 209-217.
    • (2004) Neurochem Res , vol.29 , pp. 209-217
    • Waniewski, R.A.1    Martin, D.L.2
  • 77
    • 0034666454 scopus 로고    scopus 로고
    • Astrocytic glycogen influences axon function and survival during glucose deprivation in central white matter
    • Wender R, Brown AM, Fern R, Swanson RA, Farrell K & Ransom BR (2000). Astrocytic glycogen influences axon function and survival during glucose deprivation in central white matter. J Neurosci 20, 6804-6810.
    • (2000) J Neurosci , vol.20 , pp. 6804-6810
    • Wender, R.1    Brown, A.M.2    Fern, R.3    Swanson, R.A.4    Farrell, K.5    Ransom, B.R.6
  • 78
    • 67749133881 scopus 로고    scopus 로고
    • Studies on the dids binding site of monocarboxylate transporter 1 suggest a homology model of the open conformation and a plausible translocation cycle
    • Wilson MC, Meredith D, Bunnun C, Sessions RB & Halestrap AP (2009). Studies on the dids binding site of monocarboxylate transporter 1 suggest a homology model of the open conformation and a plausible translocation cycle. J Biol Chem 284, 20011-20021.
    • (2009) J Biol Chem , vol.284 , pp. 20011-20021
    • Wilson, M.C.1    Meredith, D.2    Bunnun, C.3    Sessions, R.B.4    Halestrap, A.P.5
  • 79
    • 22844442936 scopus 로고    scopus 로고
    • Basigin (CD147) is the target for organomercurial inhibition of monocarboxylate transporter isoforms 1 and 4: the ancillary protein for the insensitive MCT2 is Embigin (gp70)
    • Wilson MC, Meredith D, Manning Fox JE, Manoharan C, Davies AJ & Halestrap AP (2005). Basigin (CD147) is the target for organomercurial inhibition of monocarboxylate transporter isoforms 1 and 4: the ancillary protein for the insensitive MCT2 is Embigin (gp70). J Biol Chem 280, 27213-27221.
    • (2005) J Biol Chem , vol.280 , pp. 27213-27221
    • Wilson, M.C.1    Meredith, D.2    Manning Fox, J.E.3    Manoharan, C.4    Davies, A.J.5    Halestrap, A.P.6


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