Development of transgenic cloned pig models of skin inflammation by DNA transposon-directed ectopic expression of human β1 and α2 integrin

PLoS ONE

Volumn 7, Issue 5, 2012, Pages

  Staunstrup, Nicklas Heine ^a   Madsen, Johannes ^b   Primo, Maria Nascimento ^a   Li, Juan ^a   Liu, Ying ^a,c   Kragh, Peter M ^a   Li, Rong ^a   Schmidt, Mette ^d   Purup, Stig ^a   Dagnæs Hansen, Frederik ^a   Svensson, Lars ^b   Petersen, Thomas K ^b   Callesen, Henrik ^a   Bolund, Lars ^a,e   Mikkelsen, Jacob Giehm ^a  

^a AARHUS UNIVERSITY   (Denmark)

^b LEO Pharma ^*  (Denmark)

^c NANJING AGRICULTURAL UNIVERSITY   (China)

^d UNIVERSITY OF COPENHAGEN   (Denmark)

^e HuaDa JiYin (BGI)   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA2 INTEGRIN; BETA1 INTEGRIN; INTERLEUKIN 1ALPHA; MITOGEN ACTIVATED PROTEIN KINASE; MOLECULAR MARKER; PROTEIN C FOS; BIOLOGICAL MARKER;

ANIMAL CELL; ANIMAL EMBRYO; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CELL MEMBRANE; CELL NUCLEUS TRANSPLANTATION; CONTROLLED STUDY; DISEASE MODEL; FIBROBLAST; HUMAN; HUMAN CELL; KERATINOCYTE; MOLECULAR CLONING; NONHUMAN; PHENOTYPE; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SKIN BIOPSY; SKIN INFLAMMATION; SOMATIC CELL; TRANSGENIC PIG; TRANSPOSON; ANIMAL; BIOSYNTHESIS; CLONING; DERMATITIS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MINIPIG; PATHOLOGY; PSORIASIS; SWINE; TRANSGENIC ANIMAL;

ANIMALIA; SUIDAE; SUS;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; ANTIGENS, CD29; BIOLOGICAL MARKERS; CLONING, ORGANISM; DERMATITIS; DISEASE MODELS, ANIMAL; DNA TRANSPOSABLE ELEMENTS; GENE EXPRESSION REGULATION; HUMANS; INTEGRIN ALPHA2; KERATINOCYTES; PSORIASIS; SWINE; SWINE, MINIATURE;

EID: 84860999625     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0036658     Document Type: Article

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