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Volumn 70, Issue 2, 2012, Pages 491-496

O-6-methylguanine-DNA methyltransferase (MGMT) immunohistochemical expression in pituitary corticotroph adenomas

Author keywords

Crooke cell adenoma; Cushing disease; MGMT; Pituitary adenoma; Silent corticotroph adenoma; Temozolomide

Indexed keywords

METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; TEMOZOLOMIDE; CORTICOTROPIN; DNA METHYLTRANSFERASE; MGMT PROTEIN, HUMAN; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; TUMOR MARKER; TUMOR SUPPRESSOR PROTEIN;

EID: 84860920334     PISSN: 00694827     EISSN: 0148396X     Source Type: Journal    
DOI: 10.1227/NEU.0b013e318230ac63     Document Type: Article
Times cited : (26)

References (38)
  • 1
    • 0141682710 scopus 로고    scopus 로고
    • Crooke's cell adenoma of the pituitary: An aggressive variant of corticotroph adenoma
    • George DH, Scheithauer BW, Kovacs K, et al. Crooke's cell adenoma of the pituitary: an aggressive variant of corticotroph adenoma. Am J Surg Pathol. 2003; 27(10):1330-1336.
    • (2003) Am J Surg Pathol. , vol.27 , Issue.10 , pp. 1330-1336
    • George, D.H.1    Scheithauer, B.W.2    Kovacs, K.3
  • 2
    • 33947513244 scopus 로고    scopus 로고
    • Mortality in patients treated for Cushing's disease is increased, compared with patients treated for nonfunctioning pituitary macroadenoma
    • Dekkers OM, Biermasz NR, Pereira AM, et al. Mortality in patients treated for Cushing's disease is increased, compared with patients treated for nonfunctioning pituitary macroadenoma. J Clin Endocrinol Metab. 2007;92(3):976-981.
    • (2007) J Clin Endocrinol Metab. , vol.92 , Issue.3 , pp. 976-981
    • Dekkers, O.M.1    Biermasz, N.R.2    Pereira, A.M.3
  • 3
    • 0029650769 scopus 로고
    • Cushing's syndrome
    • Orth DN. Cushing's syndrome. N Engl J Med. 1995;332(12):791-803.
    • (1995) N Engl J Med. , vol.332 , Issue.12 , pp. 791-803
    • Orth, D.N.1
  • 4
    • 64849098882 scopus 로고    scopus 로고
    • Outcomes after repeat transsphenoidal surgery for recurrent Cushing's disease
    • discussion 270-261
    • Patil CG, Veeravagu A, Prevedello DM, Katznelson L, Vance ML, Laws ER Jr. Outcomes after repeat transsphenoidal surgery for recurrent Cushing's disease. Neurosurgery. 2008;63(2):266-270; discussion 270-261.
    • (2008) Neurosurgery , vol.63 , Issue.2 , pp. 266-270
    • Patil, C.G.1    Veeravagu, A.2    Prevedello, D.M.3    Katznelson, L.4    Vance, M.L.5    Laws, E.R.6
  • 5
    • 29044438414 scopus 로고    scopus 로고
    • Prognostic indicators in an aggressive pituitary Crooke's cell adenoma
    • Kovacs K, Diep CC, Horvath E, et al. Prognostic indicators in an aggressive pituitary Crooke's cell adenoma. Can J Neurol Sci. 2005;32(4):540-545.
    • (2005) Can J Neurol Sci. , vol.32 , Issue.4 , pp. 540-545
    • Kovacs, K.1    Diep, C.C.2    Horvath, E.3
  • 6
    • 0034525817 scopus 로고    scopus 로고
    • Clinically silent corticotroph tumors of the pituitary gland
    • discussion 729-730
    • Scheithauer BW, Jaap AJ, Horvath E, et al. Clinically silent corticotroph tumors of the pituitary gland. Neurosurgery. 2000;47(3):723-729; discussion 729-730.
    • (2000) Neurosurgery , vol.47 , Issue.3 , pp. 723-729
    • Scheithauer, B.W.1    Jaap, A.J.2    Horvath, E.3
  • 7
    • 38149032511 scopus 로고    scopus 로고
    • MGMT immunoexpression predicts responsiveness of pituitary tumors to temozolomide therapy
    • Kovacs K, Scheithauer BW, Lombardero M, et al. MGMT immunoexpression predicts responsiveness of pituitary tumors to temozolomide therapy. Acta Neuropathol. 2008;115(2):261-262.
    • (2008) Acta Neuropathol. , vol.115 , Issue.2 , pp. 261-262
    • Kovacs, K.1    Scheithauer, B.W.2    Lombardero, M.3
  • 8
    • 67649839955 scopus 로고    scopus 로고
    • Use of temozolomide in aggressive pituitary tumors: Case report
    • discussion E774
    • Mohammed S, Kovacs K, Mason W, Smyth H, Cusimano MD. Use of temozolomide in aggressive pituitary tumors: case report. Neurosurgery. 2009;64 (4):E773-E774; discussion E774.
    • (2009) Neurosurgery , vol.64 , Issue.4 , pp. E773-E774
    • Mohammed, S.1    Kovacs, K.2    Mason, W.3    Smyth, H.4    Cusimano, M.D.5
  • 9
    • 58249085543 scopus 로고    scopus 로고
    • Treatment of Nelson's syndrome with temozolomide
    • Moyes VJ, Alusi G, Sabin HI, et al. Treatment of Nelson's syndrome with temozolomide. Eur J Endocrinol. 2009;160(1):115-119.
    • (2009) Eur J Endocrinol. , vol.160 , Issue.1 , pp. 115-119
    • Moyes, V.J.1    Alusi, G.2    Sabin, H.I.3
  • 10
    • 44449147948 scopus 로고    scopus 로고
    • Role of mismatch repair and MGMT in response to anticancer therapies
    • Casorelli I, Russo MT, Bignami M. Role of mismatch repair and MGMT in response to anticancer therapies. Anticancer Agents Med Chem. 2008;8(4):368-380.
    • (2008) Anticancer Agents Med Chem. , vol.8 , Issue.4 , pp. 368-380
    • Casorelli, I.1    Russo, M.T.2    Bignami, M.3
  • 11
    • 51649117107 scopus 로고    scopus 로고
    • Correlation of O6-methylguanine methyltransferase (MGMT) promoter methylation with clinical outcomes in glioblastoma and clinical strategies to modulate MGMT activity
    • Hegi ME, Liu L, Herman JG, et al. Correlation of O6-methylguanine methyltransferase (MGMT) promoter methylation with clinical outcomes in glioblastoma and clinical strategies to modulate MGMT activity. J Clin Oncol. 2008;26(25):4189-4199.
    • (2008) J Clin Oncol. , vol.26 , Issue.25 , pp. 4189-4199
    • Hegi, M.E.1    Liu, L.2    Herman, J.G.3
  • 12
    • 40849124057 scopus 로고    scopus 로고
    • O6-methylguanine-DNA methyltransferase inactivation and chemotherapy
    • Verbeek B, Southgate TD, Gilham DE, Margison GP. O6-methylguanine-DNA methyltransferase inactivation and chemotherapy. Br Med Bull. 2008;85:17-33.
    • (2008) Br Med Bull. , vol.85 , pp. 17-33
    • Verbeek, B.1    Southgate, T.D.2    Gilham, D.E.3    Margison, G.P.4
  • 13
    • 34248198326 scopus 로고    scopus 로고
    • Correlation between O6-methylguanine-DNA methyltransferase and survival in inoperable newly diagnosed glioblastoma patients treated with neoadjuvant temozolomide
    • Chinot OL, Barrie M, Fuentes S, et al. Correlation between O6-methylguanine-DNA methyltransferase and survival in inoperable newly diagnosed glioblastoma patients treated with neoadjuvant temozolomide. J Clin Oncol. 2007;25(12): 1470-1475.
    • (2007) J Clin Oncol. , vol.25 , Issue.12 , pp. 1470-1475
    • Chinot, O.L.1    Barrie, M.2    Fuentes, S.3
  • 14
    • 34249053906 scopus 로고    scopus 로고
    • MGMT prognostic impact on glioblastoma is dependent on therapeutic modalities
    • Criniere E, Kaloshi G, Laigle-Donadey F, et al. MGMT prognostic impact on glioblastoma is dependent on therapeutic modalities. J Neurooncol. 2007;83(2): 173-179.
    • (2007) J Neurooncol. , vol.83 , Issue.2 , pp. 173-179
    • Criniere, E.1    Kaloshi, G.2    Laigle-Donadey, F.3
  • 15
    • 34249021494 scopus 로고    scopus 로고
    • Methylation of O6-methylguanine DNA methyltransferase and loss of heterozygosity on 19q and/or 17p are overlapping features of secondary glioblastomas with prolonged survival
    • Eoli M, Menghi F, Bruzzone MG, et al. Methylation of O6-methylguanine DNA methyltransferase and loss of heterozygosity on 19q and/or 17p are overlapping features of secondary glioblastomas with prolonged survival. Clin Cancer Res. 2007; 13(9):2606-2613.
    • (2007) Clin Cancer Res. , vol.13 , Issue.9 , pp. 2606-2613
    • Eoli, M.1    Menghi, F.2    Bruzzone, M.G.3
  • 16
    • 0034626988 scopus 로고    scopus 로고
    • Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents
    • Esteller M, Garcia-Foncillas J, Andion E, et al. Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents. N Engl J Med. 2000;343(19):1350-1354.
    • (2000) N Engl J Med. , vol.343 , Issue.19 , pp. 1350-1354
    • Esteller, M.1    Garcia-Foncillas, J.2    Andion, E.3
  • 17
    • 38749146312 scopus 로고    scopus 로고
    • Prognostic significance of O6-methylguanine-DNA methyltransferase protein expression in patients with recurrent glioblastoma treated with temozolomide
    • Nagane M, Kobayashi K, Ohnishi A, Shimizu S, Shiokawa Y. Prognostic significance of O6-methylguanine-DNA methyltransferase protein expression in patients with recurrent glioblastoma treated with temozolomide. Jpn J Clin Oncol. 2007;37(12):897-906.
    • (2007) Jpn J Clin Oncol. , vol.37 , Issue.12 , pp. 897-906
    • Nagane, M.1    Kobayashi, K.2    Ohnishi, A.3    Shimizu, S.4    Shiokawa, Y.5
  • 18
    • 33746860420 scopus 로고    scopus 로고
    • O6-methylguanine-DNA methyltransferase expression strongly correlates with outcome in childhood malignant gliomas: Results from the CCG-945 Cohort
    • Pollack IF, Hamilton RL, Sobol RW, et al. O6-methylguanine-DNA methyltransferase expression strongly correlates with outcome in childhood malignant gliomas: results from the CCG-945 Cohort. J Clin Oncol. 2006;24(21): 3431-3437.
    • (2006) J Clin Oncol. , vol.24 , Issue.21 , pp. 3431-3437
    • Pollack, I.F.1    Hamilton, R.L.2    Sobol, R.W.3
  • 19
    • 62449258056 scopus 로고    scopus 로고
    • Recurrence pattern after temozolomide concomitant with and adjuvant to radiotherapy in newly diagnosed patients with glioblastoma: Correlation with MGMT promoter methylation status
    • Brandes AA, Tosoni A, Franceschi E, et al. Recurrence pattern after temozolomide concomitant with and adjuvant to radiotherapy in newly diagnosed patients with glioblastoma: correlation with MGMT promoter methylation status. J Clin Oncol. 2009;27(8):1275-1279.
    • (2009) J Clin Oncol. , vol.27 , Issue.8 , pp. 1275-1279
    • Brandes, A.A.1    Tosoni, A.2    Franceschi, E.3
  • 20
    • 62449086667 scopus 로고    scopus 로고
    • Long-term survival of patients with glioblastoma treated with radiotherapy and lomustine plus temozolomide
    • Glas M, Happold C, Rieger J, et al. Long-term survival of patients with glioblastoma treated with radiotherapy and lomustine plus temozolomide. J Clin Oncol. 2009;27(8):1257-1261.
    • (2009) J Clin Oncol. , vol.27 , Issue.8 , pp. 1257-1261
    • Glas, M.1    Happold, C.2    Rieger, J.3
  • 21
    • 58949090060 scopus 로고    scopus 로고
    • Phase II study of protracted daily temozolomide for low-grade gliomas in adults
    • Kesari S, Schiff D, Drappatz J, et al. Phase II study of protracted daily temozolomide for low-grade gliomas in adults. Clin Cancer Res. 2009;15(1): 330-337.
    • (2009) Clin Cancer Res. , vol.15 , Issue.1 , pp. 330-337
    • Kesari, S.1    Schiff, D.2    Drappatz, J.3
  • 22
    • 58849093671 scopus 로고    scopus 로고
    • O6-methylguanine DNA methyltransferase deficiency and response to temozolomide-based therapy in patients with neuroendocrine tumors
    • Kulke MH, Hornick JL, Frauenhoffer C, et al. O6-methylguanine DNA methyltransferase deficiency and response to temozolomide-based therapy in patients with neuroendocrine tumors. Clin Cancer Res. 2009;15(1):338-345.
    • (2009) Clin Cancer Res. , vol.15 , Issue.1 , pp. 338-345
    • Kulke, M.H.1    Hornick, J.L.2    Frauenhoffer, C.3
  • 23
    • 59149086517 scopus 로고    scopus 로고
    • Phase II study of erlotinib plus temozolomide during and after radiation therapy in patients with newly diagnosed glioblastoma multiforme or gliosarcoma
    • Prados MD, Chang SM, Butowski N, et al. Phase II study of erlotinib plus temozolomide during and after radiation therapy in patients with newly diagnosed glioblastoma multiforme or gliosarcoma. J Clin Oncol. 2009;27(4):579-584.
    • (2009) J Clin Oncol. , vol.27 , Issue.4 , pp. 579-584
    • Prados, M.D.1    Chang, S.M.2    Butowski, N.3
  • 24
    • 65349121788 scopus 로고    scopus 로고
    • Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial
    • Stupp R, Hegi ME, Mason WP, et al. Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial. Lancet Oncol. 2009;10(5):459-466.
    • (2009) Lancet Oncol. , vol.10 , Issue.5 , pp. 459-466
    • Stupp, R.1    Hegi, M.E.2    Mason, W.P.3
  • 25
    • 51249098488 scopus 로고    scopus 로고
    • Anti-O6-methylguanine-methyltransferase (MGMT) immunohistochemistry in glioblastoma multiforme: Observer variability and lack of association with patient survival impede its use as clinical biomarker
    • Preusser M, Charles Janzer R, Felsberg J, et al. Anti-O6-methylguanine-methyltransferase (MGMT) immunohistochemistry in glioblastoma multiforme: observer variability and lack of association with patient survival impede its use as clinical biomarker. Brain Pathol. 2008;18(4):520-532.
    • (2008) Brain Pathol. , vol.18 , Issue.4 , pp. 520-532
    • Preusser, M.1    Charles Janzer, R.2    Felsberg, J.3
  • 26
    • 33748799412 scopus 로고    scopus 로고
    • Antitumour effects of temozolomide in a man with a large, invasive prolactin-producing pituitary neoplasm
    • Syro LV, Uribe H, Penagos LC, et al. Antitumour effects of temozolomide in a man with a large, invasive prolactin-producing pituitary neoplasm. Clin Endocrinol (Oxf). 2006;65(4):552-553.
    • (2006) Clin Endocrinol (Oxf) , vol.65 , Issue.4 , pp. 552-553
    • Syro, L.V.1    Uribe, H.2    Penagos, L.C.3
  • 27
    • 44449117063 scopus 로고    scopus 로고
    • Pituitary-targeted medical therapy of Cushing's disease
    • Alexandraki KI, Grossman AB. Pituitary-targeted medical therapy of Cushing's disease. Expert Opin Investig Drugs. 2008;17(5):669-677.
    • (2008) Expert Opin Investig Drugs , vol.17 , Issue.5 , pp. 669-677
    • Alexandraki, K.I.1    Grossman, A.B.2
  • 28
    • 67649982913 scopus 로고    scopus 로고
    • Non-surgical management of hormone-secreting pituitary tumors
    • Patil CG, Hayden M, Katznelson L, Chang SD. Non-surgical management of hormone-secreting pituitary tumors. J Clin Neurosci. 2009;16(8):985-993.
    • (2009) J Clin Neurosci. , vol.16 , Issue.8 , pp. 985-993
    • Patil, C.G.1    Hayden, M.2    Katznelson, L.3    Chang, S.D.4
  • 29
    • 34249019847 scopus 로고    scopus 로고
    • Combined therapy of somatostatin analogues and dopamine agonists in the treatment of pituitary tumours
    • Colao A, Filippella M, Pivonello R, Di Somma C, Faggiano A, Lombardi G. Combined therapy of somatostatin analogues and dopamine agonists in the treatment of pituitary tumours. Eur J Endocrinol. 2007;156(suppl 1):S57-S63.
    • (2007) Eur J Endocrinol. , vol.156 , pp. S57-S63
    • Colao, A.1    Filippella, M.2    Pivonello, R.3    Di Somma, C.4    Faggiano, A.5    Lombardi, G.6
  • 30
    • 34548786267 scopus 로고    scopus 로고
    • Effectiveness of interferonbeta and temozolomide combination therapy against temozolomide-refractory recurrent anaplastic astrocytoma
    • Fujimaki T, Ishii H, Matsuno A, Arai H, Nakagomi T. Effectiveness of interferonbeta and temozolomide combination therapy against temozolomide-refractory recurrent anaplastic astrocytoma. World J Surg Oncol. 2007;5:89.
    • (2007) World J Surg Oncol. , vol.5 , pp. 89
    • Fujimaki, T.1    Ishii, H.2    Matsuno, A.3    Arai, H.4    Nakagomi, T.5
  • 31
    • 0033782928 scopus 로고    scopus 로고
    • Increased susceptibility to chemotherapeutic alkylating agents of mice deficient in DNA repair methyltransferase
    • Shiraishi A, Sakumi K, Sekiguchi M. Increased susceptibility to chemotherapeutic alkylating agents of mice deficient in DNA repair methyltransferase. Carcinogenesis. 2000;21(10):1879-1883.
    • (2000) Carcinogenesis , vol.21 , Issue.10 , pp. 1879-1883
    • Shiraishi, A.1    Sakumi, K.2    Sekiguchi, M.3
  • 32
    • 67650302290 scopus 로고    scopus 로고
    • Low O6-methylguanine-DNA methyltransferase (MGMT) expression and response to temozolomide in aggressive pituitary tumours
    • McCormack AI, McDonald KL, Gill AJ, et al. Low O6-methylguanine-DNA methyltransferase (MGMT) expression and response to temozolomide in aggressive pituitary tumours. Clin Endocrinol (Oxf). 2009;71(2):226-233.
    • (2009) Clin Endocrinol (Oxf) , vol.71 , Issue.2 , pp. 226-233
    • McCormack, A.I.1    McDonald, K.L.2    Gill, A.J.3
  • 33
    • 34250802722 scopus 로고    scopus 로고
    • O6-methylguanine-DNA methyltransferase is downregulated in transformed astrocyte cells: Implications for anti-glioma therapies
    • Sasai K, Akagi T, Aoyanagi E, Tabu K, Kaneko S, Tanaka S. O6-methylguanine-DNA methyltransferase is downregulated in transformed astrocyte cells: implications for anti-glioma therapies. Mol Cancer. 2007;6(1):36.
    • (2007) Mol Cancer , vol.6 , Issue.1 , pp. 36
    • Sasai, K.1    Akagi, T.2    Aoyanagi, E.3    Tabu, K.4    Kaneko, S.5    Tanaka, S.6
  • 34
    • 70349767529 scopus 로고    scopus 로고
    • High incidence of low O(6)-methylguanine DNA methyltransferase expression in invasive macroadenomas of Cushing's disease
    • Takeshita A, Inoshita N, Taguchi M, et al. High incidence of low O(6)-methylguanine DNA methyltransferase expression in invasive macroadenomas of Cushing's disease. Eur J Endocrinol. 2009;161(4):553-559.
    • (2009) Eur J Endocrinol. , vol.161 , Issue.4 , pp. 553-559
    • Takeshita, A.1    Inoshita, N.2    Taguchi, M.3
  • 35
    • 0017797266 scopus 로고
    • Silent corticotroph cell adenoma with lysosomal accumulation and crinophagy: A distinct clinicopathologic entity
    • Kovacs K, Horvath E, Bayley TA, Hassaram ST, Ezrin C. Silent corticotroph cell adenoma with lysosomal accumulation and crinophagy: a distinct clinicopathologic entity. Am J Med. 1978;64(3):492-499.
    • (1978) Am J Med. , vol.64 , Issue.3 , pp. 492-499
    • Kovacs, K.1    Horvath, E.2    Bayley, T.A.3    Hassaram, S.T.4    Ezrin, C.5
  • 36
    • 78049497348 scopus 로고    scopus 로고
    • Temozolomide treatment for aggressive pituitary tumors: Correlation of clinical outcome with O6-methylguanine methyltransferase (MGMT) promoter methylation and expression
    • Bush ZM, Longtine JA, Cunningham T, et al. Temozolomide treatment for aggressive pituitary tumors: correlation of clinical outcome with O6-methylguanine methyltransferase (MGMT) promoter methylation and expression. J Clin Endocrinol Metab. 2010;95(11):E280-E290.
    • (2010) J Clin Endocrinol Metab. , vol.95 , Issue.11 , pp. E280-E290
    • Bush, Z.M.1    Longtine, J.A.2    Cunningham, T.3
  • 37
    • 61449125974 scopus 로고    scopus 로고
    • O(6)-methylguanine DNA methyltransferase immunoexpression in nonfunctioning pituitary adenomas: Are progressive tumors potential candidates for temozolomide treatment?
    • Widhalm G, Wolfsberger S, Preusser M, et al. O(6)-methylguanine DNA methyltransferase immunoexpression in nonfunctioning pituitary adenomas: are progressive tumors potential candidates for temozolomide treatment? Cancer. 2009;115(5):1070-1080.
    • (2009) Cancer , vol.115 , Issue.5 , pp. 1070-1080
    • Widhalm, G.1    Wolfsberger, S.2    Preusser, M.3
  • 38
    • 77957808859 scopus 로고    scopus 로고
    • Temozolomide treatment in aggressive pituitary tumors and pituitary carcinomas: A French multicenter experience
    • Raverot G, Sturm N, de Fraipont F, et al. Temozolomide treatment in aggressive pituitary tumors and pituitary carcinomas: a French multicenter experience. J Clin Endocrinol Metab. 2010;95(10):4592-4599.
    • (2010) J Clin Endocrinol Metab. , vol.95 , Issue.10 , pp. 4592-4599
    • Raverot, G.1    Sturm, N.2    De Fraipont, F.3


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