The identification of a succinyl-CoA thioesterase suggests a novel pathway for succinate production in peroxisomes

Journal of Biological Chemistry

Volumn 280, Issue 46, 2005, Pages 38125-38132

  Westin, Maria A K ^a   Hunt, Mary C ^a   Alexson, Stefan E H ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL ORGANS; CARBOXYLIC ACIDS; DEGRADATION; FATTY ACIDS; HYDROLYSIS; SYNTHESIS (CHEMICAL);

DICARBOXYLIC ACIDS; PEROXISOMES; SUCCINATE PRODUCTION; SUCCINYL-COA THIOESTERASE;

ESTERS;

DICARBOXYLIC ACID; GLUTARYL COENZYME A DEHYDROGENASE; PALMITOYL COENZYME A HYDROLASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; SUCCINIC ACID; ACOT4 PROTEIN, HUMAN; ACOT8 PROTEIN, HUMAN; FATTY ACID; GREEN FLUORESCENT PROTEIN; MESSENGER RNA; PIRINIXIC ACID; PYRIMIDINE DERIVATIVE; RECOMBINANT PROTEIN; THIOL ESTER HYDROLASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME LOCALIZATION; ENZYME SPECIFICITY; FATTY ACID OXIDATION; HYDROLYSIS; MALE; MOLECULAR CLONING; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; ORGAN DISTRIBUTION; PEROXISOME; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; SEQUENCE ANALYSIS; URINARY EXCRETION; ANIMAL; BIOLOGICAL MODEL; CHEMISTRY; ENDOPLASMIC RETICULUM; FIBROBLAST; GENE EXPRESSION REGULATION; HUMAN; KIDNEY; KINETICS; LIVER; METABOLISM; PHYSIOLOGY; POLYACRYLAMIDE GEL ELECTROPHORESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TIME; TISSUE DISTRIBUTION; TRANSGENIC MOUSE; UPREGULATION; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CLONING, MOLECULAR; DICARBOXYLIC ACIDS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENDOPLASMIC RETICULUM; FATTY ACIDS; FIBROBLASTS; GENE EXPRESSION REGULATION; GREEN FLUORESCENT PROTEINS; HUMANS; HYDROLYSIS; KIDNEY; KINETICS; LIVER; MALE; MICE; MICE, TRANSGENIC; MODELS, BIOLOGICAL; PALMITOYL-COA HYDROLASE; PEROXISOMES; PPAR ALPHA; PYRIMIDINES; RECOMBINANT PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SUBSTRATE SPECIFICITY; SUCCINIC ACID; THIOLESTER HYDROLASES; TIME FACTORS; TISSUE DISTRIBUTION; UP-REGULATION;

EID: 33644676983     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M508479200     Document Type: Article

References (58)

1. Hunt, M. C., and Alexson, S. E. H. (2002) Prog. Lipid Res. 41, 99-130
2. Berge, E. K., Flatmark, T., and Osmundsen, H. (1984) Eur. J. Biochem. 141, 637-644
3. Alexson, S. E. H., Osmundsen, H., and Berge, R. K. (1989) Biochem. J. 262, 41-46
4. Wilcke, M., and Alexson, S. E. H. (1994) Eur. J. Biochem. 222, 803-811
5. Hunt, M. C., Nousiainen, S. E. B., Huttunen, M. K., Orii, K. E., Svensson, L. T., and Alexson, S. E. H. (1999) J. Biol. Chem. 274, 34317-34326
6. Westin, M. A. K., Alexson, S. E. H., and Hunt, M. C. (2004) J. Biol. Chem. 279, 21841-21848
7. Yamada, J., Matsumoto, I. Furihata, T., Sakuma, M., and Suga, T. (1994) Arch. Biochem. Biophys. 308, 118-125
8. Svensson, L. T., Wilcke, M., and Alexson, S. E. H. (1995) Eur. J. Biochem. 813-820
9. Svensson, L. T., Alexson, S. E. H., and Hiltunen, J. K. (1995) J. Biol. Chem. 270, 12177-12183
10. Hunt, M. C., Yamada, J., Maltais, L. J., Wright, M., Podesta, E. J., and Alexson, S. E. H. (2005) J. Lipid Res. 46, 2029-2032
11. Yamada, J., Suga, K. Furihata, T., Kithara, M., Watanabe, T., Hosokawa, M., Satoh, T., and Suga, T. (1998) Biochem. Biophys. Res. Commun. 248, 608-612
12. Svensson, L. T., Engberg, S. T., Aoyama, T., Usuda, N., Alexson, S. E. H., and Hashimoto, T. (1998) Biochem. J. 329, 601-608
13. Lindquist, P. J. G., Svensson, L. T., and Alexson, S. E. H. (1998) Eur. J. Biochem. 251, 631-640
14. Hunt, M. C., Solaas, K., Kase, B. F., and Alexson, S. E. H. (2002) J. Biol. Chem. 277, 1128-1138
15. Jones, J. M., Nau, K., Geragthy, M. T., Erdmann, R. and Gould, S. J. (1999) J. Biol. Chem. 274, 9216-9223
16. Watanabe, H., Shiratori, T., Shoji, H., Miyatake, S., Okazaki, Y., Ikuta, K., Sato, T., and Saito, T. (1997) Biochem. Biophys. Res. Commun. 238, 234-239
17. Liu, L. X., Margottin, F., Le Gall, S., Schwartz, O., Selig, L., Benarous, R., and Benichou, S. (1997) J. Biol. Chem. 272, 13779-13785
18. Ofman, R., el Mrabet, L., Dacremont, G., Spijer, D., and Wanders, R. J. A. (2002) Biochem. Biophys. Res. Commun. 290, 629-634
19. Reddy, J. K., and Mannaerts, G. P. (1994) Annu. Rev. Nutr. 14, 343-370
20. Wanders, R. J. A. (2004) Mol. Genet. Metab. 83, 16-27
21. Suga, T. (2003) Drug Metab. Pharmacokinet. 18, 155-162
22. Wanders, R. J. A. (2004) Am. J. Med. Genet. A 126, 355-375
23. Reszko, A. E., Kasumov, T., David, F., Jobbins, K. A., Thomas, K. R., Hoppel, C. L., Brunengraber, H., and Des Rosiers, C. (2004) J. Biol. Chem. 279, 19574-19579
24. Bian, F., Kasumov, T., Thomas, K. R., Jobbins, K. A., David, F., Minkler, P. E., Hoppel, C. L., and Brunengraber, H. (2005) J. Biol. Chem. 280, 9265-9271
25. Kasumov, T., Adams, J. F., Bian, F., David, F., Thomas K. R., Jobbins, K. A., Minkler, P. E., Hoppel, C. L., and Brunengraber, H. (2005) Biochem. J. 389, 397-401
26. Sanders, R. J., Ofman, R., Valianpour, F., Kemp, S., and Wanders, R. J. A. (2005) J. Lipid Res. 46, 1001-1008
27. Mortensen, P. B., and Gregersen, N. (1980) Clin. Chim. Acta 103, 33-37
28. Mortensen, P. B., and Gregersen, N. (1982) Biochim. Biophys. Acta 710, 477-484
29. Gregersen, N., Kolvraa, S., Mortensen, P. B., and Rasmussen, K. (1982) Scand. J. Clin. Lab. Investig. Suppl. 161, 15-27
30. Chase, J. F. A. (1967) Biochem. J. 510-518
31. Magnes, C., Sinner, F. M., Regittnig, W., and Pieber, T. R. (2005) Anal. Chem. 77, 2889-2894
32. Bradford, M. M. (1976) Anal. Biochem. 72, 248-254
33. Hunt, M. C., Lindquist, P. J. G., Peters, J. M., Gonzalez, F. J., Diczfalusy, U., and Alexson, S. E. H. (2000) J. Lipid Res. 41, 814-823
34. Gould, S. J., Keller, G. A., Hosken, N., Wilkinson, J., and Subramani, S. (1989) J. Cell Biol. 108, 1657-1664
35. Dodt, G., Braverman, N., Wong, C., Moser, A. B., Moser, H. W., Watkins, P. A., Valle, D., and Gould, S. J. (1995) Nat. Genet. 9, 115-125
36. Singh, I. (1997) Mol. Cell. Biochem. 167, 1-29
37. Sacksteder, K. A., Morrell, J. C., Wanders, R. J. A., Matalon, R., and Gould, S. J. (1999) J. Biol. Chem. 274, 24461-24468
38. Horie, S., Ogawa, S., and Suga, T. (1989) Life Sci. 16, 1141-1148
39. Vamecq, J., de Hoffmann, E., and Van Hoof, F. (1985) Eur. J. Biochem. 146, 663-669
40. Verkade, P. E., and van der Lee, J. (1934) Biochem. J. 28, 31-40
41. Mortensen, P. B. (1980) Biochim. Biophys. Acta 620, 177-185
42. Bergseth, S., Hokland, B. M., and Bremer, J. (1988) Biochim. Biophys. Acta 961, 103-109
43. Mortensen, P. B. (1986) Biochim. Biophys. Acta 878, 14-19
44. Björkhem, I. (1976) J. Biol. Chem. 251, 5259-5266
45. Okita, R. T., and Okita, J. R. (2001) Curr. Drug Metab. 2, 265-281
46. Vamecq, J., de Hoffmann, E., and van Hoof, F. (1985) Biochem. J. 230, 683-693
47. Vamecq, J., and Draye, J. P. (1989) J. Biochem. 106, 216-222
48. Kølvraa, S., and Gregersen, N. (1986) Biochim. Biophys. Acta 876, 515-525
49. Leighton, F., Bergseth, S., Rørtveit, T., Christiansen, E. N., and Bremer, J. (1989) J. Biol. Chem. 264, 10347-10350
50. Cerdan, S., Künnecke, B., Dölle, A., and Seelig, J. (1988) J. Biol. Chem. 263, 11664-11674
51. Mortensen, P. B., Kølvraa, S., Gregersen, N., and Rasmussen, K. (1982) Biochim. Biophys. Acta 713, 393-397
52. Ferdinandusse, S., Denis, S., Van Roermund, C. W. T., Wanders, R. J. A., and Dacremont, G. (2004) J. Lipid Res. 45, 1104-1111
53. Vamecq, J., Draye, J. P., and Brison, J. (1989) Am. J. Physiol. 256, 680-688
54. Lee, S. S., Pineau, T., Drago, J., Lee, E. J., Owens, J. W., Kroetz, D. L., Fernandez-Salguero, P. M., Westphal, H., and Gonzalez, F. J. (1995) Mol. Cell. Biol. 15, 3012-3022
55. Björkhem, I., Blomstrand, S., Hågå, P., Kase, B. F., Palonek, E., Pedersen, J. I., Strandvik, B., and Wikström, S. Å. (1984) Biochim. Biophys. Acta 795, 15-19
56. Rocchiccioli, F., Aubourg, P., and Bourgneres, P. F. (1986) Pediatr. Res. 20, 62-66
57. Korman, S. H., Mandel, H., and Gutman, A. (2000) J. Inherit. Metab. Dis. 23, 425-428
58. Wada, F., and Usami, M. (1977) Biochim. Biophys. Acta 487, 361-368