Toll-like receptors 2 and 4 impair insulin-mediated brain activity by interleukin-6 and osteopontin and alter sleep architecture

FASEB Journal

Volumn 26, Issue 5, 2012, Pages 1799-1809

  Sartorius, Tina ^a   Lutz, Stefan Z ^a   Hoene, Miriam ^a   Waak, Jens ^b,c   Peter, Andreas ^a   Weigert, Cora ^a   Rammensee, Hans Georg ^a   Kahle, Philipp J ^b   Häring, Hans Ulrich ^a   Hennige, Anita M ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b UNIVERSITY OF TÜBINGEN   (Germany)

^c Nexigen   (Germany)

Author keywords

Locomotion; TLR2 4

Indexed keywords

FATTY ACID; GLUCOSE; HUMAN INSULIN; INTERLEUKIN 6; MESSENGER RNA; NEUTRALIZING ANTIBODY; OSTEOPONTIN; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTE; BLOOD GLUCOSE METER; BODY WEIGHT; BRAIN; BRAIN CORTEX; CONTROLLED STUDY; DISEASE COURSE; ELECTROCORTICOGRAPHY; ENZYME LINKED IMMUNOSORBENT ASSAY; GLUCOSE METABOLISM; GLUCOSE TOLERANCE; HORMONE ACTION; IMPAIRED GLUCOSE TOLERANCE; IMPLANT; INSULIN RESISTANCE; INSULIN TOLERANCE TEST; LIPID DIET; LOCOMOTION; METABOLIC REGULATION; MOUSE; NERVE CELL CULTURE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SLEEP; SLEEP WAKING CYCLE; TELEMETRY;

ANIMALS; ASTROCYTES; BRAIN; CELLS, CULTURED; ELECTROENCEPHALOGRAPHY; GLUCOSE TOLERANCE TEST; INSULIN; INSULIN RESISTANCE; INTERLEUKIN-6; LOCOMOTION; MICE; MICE, INBRED C3H; MICE, KNOCKOUT; OSTEOPONTIN; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; REAL-TIME POLYMERASE CHAIN REACTION; SLEEP; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4;

MUS;

EID: 84860903172     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.11-191023     Document Type: Article

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