Subclinical mucosal inflammation in diarrhea-predominant irritable bowel syndrome (IBS) in a tropical setting

Scandinavian Journal of Gastroenterology

Volumn 47, Issue 6, 2012, Pages 619-624

  De Silva, Arjuna Priyadarsin ^a   Nandasiri, Shanika Dulanjalee ^a   Hewavisenthi, Janaki ^a   Manamperi, Aresha ^a   Ariyasinghe, Madurangi Prasadi ^a   Dassanayake, Anuradha Supun ^a   Jewell, Derek P ^b   De Silva, Hithanadura Janaka ^a  

^a UNIVERSITY OF KELANIYA   (Sri Lanka)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

cytokines; eosinophils; IBS; IBS D; inflammation; mast cells

Indexed keywords

CALGRANULIN; INTERLEUKIN 10; INTERLEUKIN 8;

ADULT; ARTICLE; CECUM; CLINICAL ARTICLE; COLON; COLON CANCER; CONTROLLED STUDY; CORRELATION ANALYSIS; DIARRHEA; EOSINOPHIL; FECES ANALYSIS; HUMAN; HUMAN TISSUE; ILEUM; INFECTIOUS DIARRHEA; INTESTINE MUCOSA; IRRITABLE COLON; LYMPHOCYTE; MAST CELL; MUCOSA INFLAMMATION; NEUTROPHIL; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN EXPRESSION; RANK SUM TEST; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADOLESCENT; ADULT; BIOLOGICAL MARKERS; BIOPSY; CASE-CONTROL STUDIES; COLON; COLONOSCOPY; DIARRHEA; EOSINOPHILS; FEMALE; GASTROENTERITIS; HUMANS; ILEUM; INTERLEUKIN-10; INTERLEUKIN-8; INTESTINAL MUCOSA; IRRITABLE BOWEL SYNDROME; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SRI LANKA; TROPICAL CLIMATE; YOUNG ADULT;

EID: 84860876219     PISSN: 00365521     EISSN: 15027708     Source Type: Journal    
DOI: 10.3109/00365521.2012.666672     Document Type: Article

References (29)

1. Drossman DA, Camilleri M, Mayer EA, Whitehead WE. AGA technical review on irritable bowel syndrome. Gastroenterology 2002;123:2108-31.
2. Creed F, Guthrie E. Psychological factors in the irritable bowel syndrome. Gut 1987;28:1307-18.
3. Villani AC, Lemire M, Thabane M, Belisle A, Geneau G, Garg AX, et al. Genetic risk factors for post-infectious irritable bowel syndrome following a waterborne outbreak of gastroenteritis. Gastroenterology 2010;138:1502-13.
4. Whitehead WE, Palssan O, Jones KR. Systemic review of irritable bowel syndrome with other disorders: what are the causes and implications? Gastroenterology 2007;133: 799-807.
5. Neal KR, Barker L, Spiller RC. Prognosis in post-infective irritable bowel syndrome: a six year follow up study. Gut 2002;51:410-13.
6. Spiller R. Serotonin, inflammation, and IBS: fitting the jigsaw together. J Pediatr Gastrtoenterol Nutr 2007;45: 115-19.
7. Kristjánsson G, Venge P, Wanders A, Loof L, Hallgren R. Clinical and subclinical intestinal inflammation assessed by the mucosal patch technique: studies of mucosal neutrophil and eosinophil activation in inflammatory bowel diseases and irritable bowel syndrome. Gut 2004;53:1806-12.
8. Lee KJ, Kim YB, Kim JH, Kwon HC, Kim DK, Cho SW. The alteration of enterochromaffin cell, mast cell, and lamina propria T lymphocyte numbers in irritable bowel syndrome and its relationship with psychological factors. J. Gastroenterol. Hepatol 2008;23:1689-94.
9. Tobias L, Adam B, Bredack C, Roth A, Heinzel S, Lesster S, et al. Immune activation in patients with irritable bowel syndrome. Gastroenterology 2007;132:913-20.
10. Malefyt RdeW, Abrams J, Bennett B, Figdor CG, de Vries JE. Interleukin 10 (IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes. J Environ Monit 1991;174:1209-20.
11. Dinan TG, Quigley EM, Ahmed SM, et al. Hypothalamicpituitary-gut axis dysregulation in irritable bowel syndrome: plasma cytokines as a potential biomarker? Gastroenterology 2006;130:304-11.
12. Bercik P, Verdu EF, Collins MS. Is irritable bowel syndrome a low-grade inflammatory bowel disease. Gastroenterol Clin North Am 2005;34:235-45.
13. Costa F, Mumolo MG, Bellini M, Romano MR, Ceccarelli L, Arpe P, et al. Role of faecal calprotectin as non-invasive marker of intestinal inflammation. Dig Liver Dis 2003;35:9642-7.
14. Wedemeyer N, Potter T, Wetzlich S, Göhde W. Flow cytometric quantification of competitive reverse transcription-PCR products. Clin Chem 2002;48:1398-405.
15. Vigano P, Somigliana E, Mangioni S, Vignali M, Vignali M, Di Blasio AM. Expression of Interleukin-10 and its receptor is up-regulated in early pregnant versus cycling human endometrium. J Clin Endocrinol Metab 2002;87:5730-6.
16. Kim HS, Lim JH, Park H, Lee SI. Increased immunoendocrine cells in intestinal mucosa of postinfectious irritable bowel syndrome patients 3 years after acute shigella infection-an observation in a small case control study. Yonsei Med J 2010;51:1976-2437.
17. Scully P, McKernan DP, Keohane J, Groeger D, Shanahan F, Dinan TG, et al. Plasma cytokine profiles in females with irritable bowel syndrome and extra-intestinal co-morbidity. This article is not included in your organization's subscription. However, you may be able to. Am J Gastroenterol 2010;105:2235-43.
18. Sullivan M, Clayton N, Breslin NP, Harman I, Bountra C, Mclaren A, et al. Increased mast cells in the irritable bowel syndrome. Neurogastroenterol Motil 2000;12:449-57.
19. Wang LH, Fang X C, Pan GZ. Bacillary dysentery as a causative factor of irritable bowel syndrome and its pathogenesis. Gut 2004;53:1096-101.
20. Tobin MC, Moparty B, Farhadi A, DeMeo MT, Bansal PJ, Keshavarzian A. Atopic irritable bowel syndrome: a novel subgroup of irritable bowel syndrome with allergic manifestations. Ann Allergy Asthma Immunol 2008;100: 49-53.
21. Bercik P, Verdu EF, Collins SM. Is irritable bowel syndrome a low-grade inflammatory bowel disease. Gastroenterol Clin North Am 2005;34:235-45.
22. Mukaida N, Shiroo M, Matsushima K. Genomic structure of the human monocyte-derived neutrophil chemotactic factor IL-8. J Immunol 1989;143:1366-71.
23. Malefyt RdeW, Abrams J, Bennett B, Figdor CG, de Vries JE. Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10-produced by monocytes. J Exp Med 1991;174:51209-20.
24. Shefler I, Salamon P, Reshef T, Mor A, Mekori YA. T Cell-induced mast cell activation: a role for microparticles released from activated t cells. J Immunol 2010;185: 4206-12.
25. Kim GY, Lee JW, Ryu HC, Wei JD, Seong CM, Kim JH. Proinflammatory cytokine IL-1b stimulates IL-8 synthesis in Mast cells via a leukotriene B4 receptor 2-linked pathway, contributing to angiogenesis. J Immunol 2010;184: 3946-54.
26. Carvalho RFDS, Nilsson G, Harvima IT. Increased mast cell expression of PAR-2 in skin inflammatory diseases and release of IL-8 upon PAR-2 activation. Exp Dermatol 2010;192:117-22.
27. Blatner NR, Bonertz A, Beckhove P, Cheon EC, Krantz SB, Strouch M, et al. In colorectal cancer mast cells contribute to systemic regulatory T-cell dysfunction. PNAS 2010;107: 6430-5.
28. Rozell MD, Erger RA, Casale TB. Isolation technique alters eosinophil migration response to IL-8. J Immunol Methods 1996;197:97-107.
29. Furuta GT, Ackerman SJ, Varga J, Spiess AM, Wang MY, Wershil BK. Eosinophil granule-derived major basic protein induces IL-8 expression in human intestinal myofibroblasts. Clin Exp Immunol 2000;122:35-40.