Caffeic acid phenethyl ester protects nigral dopaminergic neurons via dual mechanisms involving haem oxygenase-1 and brain-derived neurotrophic factor

British Journal of Pharmacology

Volumn 166, Issue 3, 2012, Pages 1151-1168

  Kurauchi, Y ^a   Hisatsune, A ^a   Isohama, Y ^a   Mishima, S ^b   Katsuki, H ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

^b CHUBU UNIVERSITY   (Japan)

Author keywords

brain derived neurotrophic factor; caffeic acid phenethyl ester; dopaminergic neurons; heme oxygenase; neuroprotection; Nrf2; Parkinson disease

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR ANTIBODY; CAFFEIC ACID PHENETHYL ESTER; GAMMA INTERFERON; HEME OXYGENASE 1; HEME OXYGENASE INHIBITOR; LIPOPOLYSACCHARIDE; METHAMPHETAMINE; NEUTRALIZING ANTIBODY; OXIDOPAMINE; PROTOPORPHYRIN ZINC; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG EFFICACY; ENZYME ACTIVITY; FEMALE; IN VIVO STUDY; MACROPHAGE ACTIVATION; MALE; MICROGLIA; MOUSE; NEUROPROTECTION; NONHUMAN; PARKINSONISM; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; SUBSTANTIA NIGRA; UPREGULATION;

ANIMALS; BLOTTING, WESTERN; BRAIN-DERIVED NEUROTROPHIC FACTOR; CAFFEIC ACIDS; DISEASE MODELS, ANIMAL; DOPAMINERGIC NEURONS; ENZYME INDUCTION; HEME OXYGENASE-1; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, INBRED C57BL; NEUROPROTECTIVE AGENTS; NITRIC OXIDE; PARKINSONIAN DISORDERS; RATS; RATS, WISTAR; SUBSTANTIA NIGRA;

EID: 84860868425     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2012.01833.x     Document Type: Article

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