Dronedarone prevents microcirculatory abnormalities in the left ventricle during atrial tachypacing in pigs

British Journal of Pharmacology

Volumn 166, Issue 3, 2012, Pages 964-980

  Bukowska, A ^a   Hammwohner M ^b   Sixdorf, A ^a   Schild, L ^a   Wiswedel, I ^a   Rohl F W ^a   Wolke, C ^c   Lendeckel, U ^c   Aderkast, C ^c   Bochmann, S ^c   Chilukoti, R K ^c   Mostertz, J ^c   Bramlage, P ^d   Goette, A ^a,b  

^a OTTO VON GUERICKE UNIVERSITY   (Germany)

^b St Vincenz Hospital   (Germany)

^c UNIVERSITY OF GREIFSWALD   (Germany)

^d INSTITUTE FOR PHARMACOLOGY AND PREVENTIVE MEDICINE   (Germany)

Author keywords

acute coronary syndrome; atrial fibrillation; dronedarone; microcirculation

Indexed keywords

AMIODARONE; DRONEDARONE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; ISOPROSTANE DERIVATIVE; MESSENGER RNA; PLACEBO; PROTEIN KINASE C ALPHA; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BETA ACTIN GENE; CCL2 GENE; CONTROLLED STUDY; CORONARY ARTERY OBSTRUCTION; CORONARY FLOW RESERVE; DNAJB9 GENE; DRUG MECHANISM; DRUG TARGETING; EXPERIMENTAL PIG; FRACTIONAL FLOW RESERVE; GENE EXPRESSION; HEART ATRIUM FIBRILLATION; HEART ATRIUM PACING; HEART LEFT VENTRICLE; HEART MUSCLE CELL; HIF 1ALPHA GENE; LEFT ANTERIOR DESCENDING CORONARY ARTERY; MARKER GENE; MASS FRAGMENTOGRAPHY; MICROCIRCULATION; NONHUMAN; OXIDATIVE STRESS; PPARGC1 GENE; PRIORITY JOURNAL; PRKAG2 GENE; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PRX1 GENE; PRX3 GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SHAM PROCEDURE; TISSUE DISTRIBUTION; VEGF A GENE; WESTERN BLOTTING;

ACUTE CORONARY SYNDROME; AMIODARONE; ANIMALS; ANTI-ARRHYTHMIA AGENTS; ATRIAL FIBRILLATION; BLOTTING, WESTERN; CARDIAC PACING, ARTIFICIAL; CELL LINE; CORONARY CIRCULATION; GENE EXPRESSION; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MICE; MICROCIRCULATION; MYOCYTES, CARDIAC; NADPH OXIDASE; OXIDATIVE STRESS; PHOSPHORYLATION; PROTEIN KINASE C; REAL-TIME POLYMERASE CHAIN REACTION; SWINE;

EID: 84860865836     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2011.01784.x     Document Type: Article

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