Identification of two prokineticin cDNAs: Recombinant proteins potently contract gastrointestinal smooth muscle

Molecular Pharmacology

Volumn 59, Issue 4, 2001, Pages 692-698

  Li, M ^a   Bullock, C M ^a   Knauer, D J ^a   Ehlert, F J ^a   Zhou, Q Y ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; COMPLEMENTARY DNA; NEUROTRANSMITTER; PROKINETIC AGENT; RECOMBINANT PROTEIN; SNAKE VENOM;

AMINO TERMINAL SEQUENCE; ARTICLE; BREATHING MUSCLE; DRUG POTENCY; ESCHERICHIA COLI; HUMAN; HUMAN TISSUE; IODINATION; LIGAND BINDING; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN FOLDING; RECEPTOR BINDING; SKIN SECRETION; SMOOTH MUSCLE;

EID: 0035064732     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.59.4.692     Document Type: Article

References (40)

1. A prokinetic approach to treatment of gastroesophageal reflux disease
2. Gapped BLAST and PSI-BLAST: A new generation of protein database search programs
3. A colipase fold in the carboxy-terminal domain of the Wnt antagonists - The Dickkopfs
4. A structural homologue of colipase in black mamba venom revealed by NMR floating disulphide bridge analysis
5. Idiopathic constipation: Too few stools and too little knowledge
6. Is gastrin releasing peptide mammalian bombesin?
7. Neurotransmission and neurotransmitters
8. Muscarinic receptor subtypes and smooth muscle function
9. Muscarinic receptors and gastrointestinal smooth muscle
10. Motility and regulatory peptides
11. Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphrenylglycoluril
12. Expression of correctly folded proteins in Escherichia coli
13. G proteins: Transducers of receptor-generated signals
14. Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction
15. Functional and structural complexity of signal transduction via G-protein-coupled receptors
16. A new method for predicting signal sequence cleavage site
17. Mechanisms of smooth muscle contraction
18. Modulation of dopamine D(2) receptor signaling by actin-binding protein (ABP-280)
19. High-accuracy molecular mass determination for peptides and proteins by Fourier transform mass spectrometry
20. Advances in refolding of proteins produced in E. coli
21. Proteolysis in neuropeptide processing and other neural functions
22. Characterization of a gastrin releasing peptide from porcine non-antral gastric tissue
23. Bv8, a small protein from frog skin and its homologue from snake venom induce hyperalgesia in rats
24. Abnormal gastric and small intestinal motor function in diabetes mellitus
25. G protein-coupled receptors in gastrointestinal physiology. IV. Neural regulation of gastrointestinal smooth muscle
26. Contractile role of the M2 and M3 muscarinic receptors in the guinea pig colon
27. Purification and pharmacological characterization of peptide toxins from the black mamba (Dendroaspis polylepis) venom
28. MIT(1), a black mamba toxin with a new and highly potent activity on intestinal contraction
29. A new member of the natriuretic peptide family is present in the venom of the green mamba (Dendroaspis angusticeps)
30. Analysis of the motor effects of 13-norleucine motilin on the rabbit, guinea pig, rat, and human alimentary tract in vitro
31. Sarafotoxins S6: Several isotoxins from Atractaspis engaddensis (burrowing asp) venom that affect the heart
32. Functional role for the M2 muscarinic receptor in smooth muscle of guinea pig ileum
33. Involvement of the M2 muscarinic receptor in contractions of the guinea pig trachea, guinea pig esophagus and rat fundus
34. A reassessment of the low molecular weight phospholipase A2 gene family in mammals
35. Recent advances in the pharmacology of gastrointestinal prokinetics
36. Structure of the pancreatic lipase-procolipase complex
37. The cytokines: An overview
38. The mammalian homologues of frog Bv8 are mainly expressed in spermatocytes
39. Physiology of the enteric nervous system
40. Related articles, protein, nucleotide primary structure, synthesis, and biological activity of rat endothelin, an endothelium-derived vasoconstrictor peptide