Human T-cell lymphotropic virus type I Tax activates lung resistance-related protein expression in leukemic clones established from an adult T-cell leukemia patient

Experimental Hematology

Volumn 30, Issue 4, 2002, Pages 340-345

  Sakaki, Yoshimune ^a   Terashi, Kenji ^a   Yamaguchi, Akihiko ^a   Kawamata, Nakaaki ^a   Tokito, Yuichi ^a   Mori, Hiroyasu ^a   Umehara, Megumi ^a   Yoshiyama, Takeshi ^a   Ohtsubo, Hideo ^a   Arimura, Kosei ^a   Arima, Naomichi ^a   Tei, Chuwa ^a  

^a KAGOSHIMA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CISPLATIN; COMPLEMENTARY DNA; DOXORUBICIN; ETOPOSIDE; LUNG RESISTANCE PROTEIN; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN 1; MULTIDRUG RESISTANCE PROTEIN 2; VINDESINE;

ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOPLASM; FLUORESCENCE MICROSCOPY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN T CELL LEUKEMIA VIRUS 1; LEUKEMIA CELL LINE; LYMPHOCYTE CLONE; MULTIDRUG RESISTANCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; T CELL LEUKEMIA;

ADULT; ANTINEOPLASTIC AGENTS; ATP-BINDING CASSETTE TRANSPORTERS; CELL COMPARTMENTATION; CLONE CELLS; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE PRODUCTS, TAX; HTLV-I INFECTIONS; HUMAN T-LYMPHOTROPIC VIRUS 1; HUMANS; MEMBRANE TRANSPORT PROTEINS; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; P-GLYCOPROTEIN; RNA, MESSENGER; TUMOR CELLS, CULTURED; VAULT RIBONUCLEOPROTEIN PARTICLES;

HUMAN T-LYMPHOTROPIC VIRUS 1;

EID: 0036214278     PISSN: 0301472X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0301-472X(02)00775-0     Document Type: Article

References (36)

1. Tax of the human T-lymphotropic virus type I transactivates promoter of the MDR-1 gene
2. Enhanced MDR1 gene expression in human T-cell leukemia virus-I-infected patients offers new prospects for therapy
3. Adult T-cell leukemia cells over-express the multidrug-resistance-protein (MRP) and lung-resistance-protein (LRP) genes
4. HTLV-I oncoprotein tax and cellular transcription factors
5. The mechanism of trans-activation of the MDR1 gene by human T-cell leukemia virus
6. Overexpression of a M(r) 110,000 vesicular protein in non-P-glycoprotein-mediated multidrug resistance
7. Evidence that vault ribonucleoprotein particles localize to the nuclear pore complex
8. Drug resistance-associated marker Lrp for prediction of response to chemotherapy and prognoses in advanced ovarian carcinoma
9. Expression of lung resistance-related protein (LRP) in non-small cell lung carcinomas of smokers and non-smokers and its predictive value for doxorubicin resistance
10. Drug resistance factors in acute myeloid leukemia: A comparative analysis
11. Quantification by laser scan microscopy of intracellular doxorubicin distribution
12. Low-level doxorubicin resistance in benzo[a]pyrene-treated KB-3-1 cells is associated with increased LRP expression and altered subcellular drug distribution
13. Multidrug resistance and the lung resistance-related protein in human colon carcinoma SW-620 cells
14. Evidence for the interleukin-2 dependent expansion of leukemic cells in adult T cell leukemia
15. Identification of HTLV-I tax trans-activator mutants exhibiting novel transcriptional phenotypes
16. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
17. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
18. Characterization of DNA polymerase from Pyococcus sp. strain KOD1 and its application to PCR
19. Human T lymphotropic virus-type I Tax induction of CD21/Epstein-Barr virus receptor expression on T cells and its significance in leukemogenesis of adult T cell leukemia
20. Characterization of a leukotriene C4 export mechanism in human platelets: Possible involvement of multidrug resistance-associated protein 1
21. Human canalicular multispecific organic anion transporter (cMOAT) is expressed in human lung, gastric, and colorectal cancer cells
22. Overexpression of the death-promoting gene bax-α which is downregulated in breast cancer restores sensitivity to different apoptotic stimuli and reduces tumor growth in SCID mice
23. Triple synergism of human T-lymphotropic virus type 1-encoded tax, GATA-binding protein, and AP-1 is required for constitutive expression of the interleukin-5 gene in adult T-cell leukemia cells
24. Human T-cell leukemia virus type 1 Tax protein induces the expression of STAT1 and STAT5 genes in T-cells
25. Cloning and initial analysis of the human multidrug resistance-related MVP/LRP gene promoter
26. Expression of P-glycoprotein in adult T-cell leukemia cells
27. Possible roles of an adult T-cell leukemia (ATL)-derived factor/thioredoxin in the drug resistance of ATL to Adriamycin
28. A family of drug transporters: The multidrug resistance-associated proteins
29. Major vault protein LRP-related multidrug resistance
30. The LRP gene encoding a major vault protein associated with drug resistance maps proximal to MRP on chromosome 16: Evidence that chromosome breakage plays a key role in MRP or LRP gene amplification
31. Conjugate export pumps of the multidrug resistance protein (MRP) family: Localization, substrate specificity, and MRP2-mediated drug resistance
32. Resistance mechanisms associated with altered intracellular distribution of anticancer agents
33. A novel quinoline derivative, MS-209, overcomes drug resistance of human lung cancer cells expressing the multidrug resistance-associated protein (MRP) gene
34. Genistein modulates the decreased drug accumulation in non-P-glycoprotein mediated multidrug resistant tumour cells
35. Inhibition of the P-glycoprotein- and multidrug resistance protein-mediated efflux of anthracyclines and calceinacetoxymethyl ester by PAK-104P
36. Reversal of LRP-associated drug resistance in colon carcinoma SW-620 cells