-
1
-
-
77954288805
-
Genetics of type 1 diabetes. What's next?
-
Pociot, F., Akolkar, B., Concannon, P., Erlich, H. A., Julier, C., Morahan, G., Nierras, C. R., Todd, J. A., Rich, S. S., and Nerup, J. (2010) Genetics of type 1 diabetes. What's next? Diabetes 59, 1561-1571
-
(2010)
Diabetes
, vol.59
, pp. 1561-1571
-
-
Pociot, F.1
Akolkar, B.2
Concannon, P.3
Erlich, H.A.4
Julier, C.5
Morahan, G.6
Nierras, C.R.7
Todd, J.A.8
Rich, S.S.9
Nerup, J.10
-
2
-
-
77951169178
-
Banting Lecture 2009, an unfinished journey. Molecular pathogenesis to prevention of type 1A diabetes
-
Eisenbarth, G. S. (2010) Banting Lecture 2009, an unfinished journey. Molecular pathogenesis to prevention of type 1A diabetes. Diabetes 59, 759-774
-
(2010)
Diabetes
, vol.59
, pp. 759-774
-
-
Eisenbarth, G.S.1
-
3
-
-
64749116743
-
Genetics of type 1A diabetes
-
Concannon, P., Rich, S. S., and Nepom, G. T. (2009) Genetics of type 1A diabetes. N. Engl. J. Med. 360, 1646-1654
-
(2009)
N. Engl. J. Med.
, vol.360
, pp. 1646-1654
-
-
Concannon, P.1
Rich, S.S.2
Nepom, G.T.3
-
4
-
-
77951926420
-
Etiology of type 1 diabetes
-
Todd, J. A. (2010) Etiology of type 1 diabetes. Immunity 32, 457-467
-
(2010)
Immunity
, vol.32
, pp. 457-467
-
-
Todd, J.A.1
-
5
-
-
0016177620
-
HL-A antigens and diabetes melittis
-
Nerup, J., Platz, P., Andersen, O. O., Christy, M., Lyngsoe, J., Poulsen, J. E., Ryder, L. P., Nielsen, L. S., Thomsen, M., and Svejgaard, A. (1974) HL-A antigens and diabetes melittis. Lancet 2, 864-866
-
(1974)
Lancet
, vol.2
, pp. 864-866
-
-
Nerup, J.1
Platz, P.2
Andersen, O.O.3
Christy, M.4
Lyngsoe, J.5
Poulsen, J.E.6
Ryder, L.P.7
Nielsen, L.S.8
Thomsen, M.9
Svejgaard, A.10
-
6
-
-
17144452354
-
A search for type 1 diabetes susceptibility genes in families from the United Kingdom
-
DOI 10.1038/991
-
Mein, C. A., Esposito, L., Dunn, M. G., Johnson, G. C., Timms, A. E., Goy, J. V., Smith, A. N., Sebag-Montefiore, L., Merriman, M. E., Wilson, A. J., Pritchard, L. E., Cucca, F., Barnett, A. H., Bain, S. C., and Todd, J. A. (1998) A search for type 1 diabetes susceptibility genes in families from the United Kingdom. Nat. Genet. 19, 297-300 (Pubitemid 28309348)
-
(1998)
Nature Genetics
, vol.19
, Issue.3
, pp. 297-300
-
-
Mein, C.A.1
Esposito, L.2
Dunn, M.G.3
Johnson, G.C.L.4
Timms, A.E.5
Goy, J.V.6
Smith, A.N.7
Sebag-Montefiore, L.8
Merriman, M.E.9
Wilson, A.J.10
Pritchard, L.E.11
Cucca, F.12
Barnett, A.H.13
Bain, S.C.14
Todd, J.A.15
-
7
-
-
0027933734
-
A genome-wide search for human type 1 diabetes susceptibility genes
-
DOI 10.1038/371130a0
-
Davies, J. L., Kawaguchi, Y., Bennett, S. T., Copeman, J. B., Cordell, H. J., Pritchard, L. E., Reed, P. W., Gough, S. C., Jenkins, S. C., and Palmer, S. M. (1994) A genome-wide search for human type 1 diabetes susceptibility genes. Nature 371, 130-136 (Pubitemid 24284009)
-
(1994)
Nature
, vol.371
, Issue.6493
, pp. 130-136
-
-
Davies, J.L.1
Kawaguchl, Y.2
Bennett, S.T.3
Copeman, J.B.4
Cordell, H.J.5
Pritchard, L.E.6
Reed, P.W.7
Gough, S.C.L.8
Jenkins, S.C.9
Palmer, S.M.10
Balfour, K.M.11
Rowe, B.R.12
Farrall, M.13
Barnett, A.H.14
Bain, S.C.15
Todd, J.A.16
-
8
-
-
33745326638
-
Multi-SNP analysis of MHC region: Remarkable conservation of HLA-A1-B8-DR3 haplotype
-
DOI 10.2337/db05-1276
-
Aly, T. A., Eller, E., Ide, A., Gowan, K., Babu, S. R., Erlich, H. A., Rewers, M. J., Eisenbarth, G. S., and Fain, P. R. (2006) Multi-SNP analysis of MHC region. Remarkable conservation of HLA-A1-B8-DR3 haplotype. Diabetes 55, 1265-1269 (Pubitemid 44195363)
-
(2006)
Diabetes
, vol.55
, Issue.5
, pp. 1265-1269
-
-
Aly, T.A.1
Eller, E.2
Ide, A.3
Gowan, K.4
Babu, S.R.5
Erlich, H.A.6
Rewers, M.J.7
Eisenbarth, G.S.8
Fain, P.R.9
-
9
-
-
33749012255
-
Extreme genetic risk for type 1A diabetes
-
DOI 10.1073/pnas.0606349103
-
Aly, T. A., Ide, A., Jahromi, M. M., Barker, J. M., Fernando, M. S., Babu, S. R., Yu, L., Miao, D., Erlich, H. A., Fain, P. R., Barriga, K. J., Norris, J. M., Rewers, M. J., and Eisenbarth, G. S. (2006) Extreme genetic risk for type 1A diabetes. Proc. Natl. Acad. Sci. U.S.A. 103, 14074-14079 (Pubitemid 44452982)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.38
, pp. 14074-14079
-
-
Aly, T.A.1
Ide, A.2
Jahromi, M.M.3
Barker, J.M.4
Fernando, M.S.5
Babu, S.R.6
Yu, L.7
Miao, D.8
Erlich, H.A.9
Fain, P.R.10
Barriga, K.I.11
Norris, J.M.12
Rewers, M.J.13
Eisenbarth, G.S.14
-
10
-
-
33846156555
-
Environmental factors in the development of Type 1 diabetes
-
DOI 10.1007/s11154-006-9024-y, Special issue on Pediatric Diabetes
-
Peng, H., and Hagopian, W. (2006) Environmental factors in the development of type 1 diabetes. Rev. Endocr. Metab. Dis. 7, 149-162 (Pubitemid 46084826)
-
(2006)
Reviews in Endocrine and Metabolic Disorders
, vol.7
, Issue.3
, pp. 149-162
-
-
Peng, H.1
Hagopian, W.2
-
11
-
-
77953860649
-
The role of epigenetics in the pathology of diabetic complications
-
Villeneuve, L. M., and Natarajan, R. (2010) The role of epigenetics in the pathology of diabetic complications. Am. J. Physiol. Renal Physiol 299, F14-25
-
(2010)
Am. J. Physiol. Renal Physiol
, vol.299
-
-
Villeneuve, L.M.1
Natarajan, R.2
-
12
-
-
58149345617
-
Immunopathogenic interaction of environmental triggers and genetic susceptibility in diabetes. Is epigenetics the missing link?
-
Litherland, S. A. (2008) Immunopathogenic interaction of environmental triggers and genetic susceptibility in diabetes. Is epigenetics the missing link? Diabetes 57, 3184-3186
-
(2008)
Diabetes
, vol.57
, pp. 3184-3186
-
-
Litherland, S.A.1
-
13
-
-
43849096855
-
Time trends in the incidence of type 1 diabetes in Finnish children: A cohort study
-
DOI 10.1016/S0140-6736(08)60765-5, PII S0140673608607655
-
Harjutsalo, V., Sjöberg, L., and Tuomilehto, J. (2008) Time trends in the incidence of type 1 diabetes in Finnish children. A cohort study. Lancet 371, 1777-1782 (Pubitemid 351697953)
-
(2008)
The Lancet
, vol.371
, Issue.9626
, pp. 1777-1782
-
-
Harjutsalo, V.1
Sjoberg, L.2
Tuomilehto, J.3
-
14
-
-
33947310031
-
Environmental epigenomics and disease susceptibility
-
DOI 10.1038/nrg2045, PII NRG2045
-
Jirtle, R. L., and Skinner, M. K. (2007) Environmental epigenomics and disease susceptibility. Nat. Rev. Genet. 8, 253-262 (Pubitemid 46439287)
-
(2007)
Nature Reviews Genetics
, vol.8
, Issue.4
, pp. 253-262
-
-
Jirtle, R.L.1
Skinner, M.K.2
-
15
-
-
0019200870
-
A low resolution structure for the histone core of the nucleosome
-
DOI 10.1038/287509a0
-
Klug, A., Rhodes, D., Smith, J., Finch, J. T., and Thomas, J. O. (1980) A low resolution structure for the histone core of the nucleosome. Nature 287, 509-516 (Pubitemid 11232848)
-
(1980)
Nature
, vol.287
, Issue.5782
, pp. 509-516
-
-
Klug, A.1
Rhodes, D.2
Smith, J.3
-
16
-
-
0034610814
-
The language of covalent histone modifications
-
DOI 10.1038/47412
-
Strahl, B. D., and Allis, C. D. (2000) The language of covalent histone modifications. Nature 403, 41-45 (Pubitemid 30038513)
-
(2000)
Nature
, vol.403
, Issue.6765
, pp. 41-45
-
-
Strahl, B.D.1
Allis, C.D.2
-
17
-
-
0035883954
-
Transcription regulation by histone methylation: Interplay between different covalent modifications of the core histone tails
-
DOI 10.1101/gad.927301
-
Zhang, Y., and Reinberg, D. (2001) Transcription regulation by histone methylation. Interplay between different covalent modifications of the core histone tails. Genes Dev. 15, 2343-2360 (Pubitemid 32899739)
-
(2001)
Genes and Development
, vol.15
, Issue.18
, pp. 2343-2360
-
-
Zhang, Y.1
Reinberg, D.2
-
18
-
-
33746324216
-
Chromatin modifications by methylation and ubiquitination. Implications in the regulation of gene expression
-
Shilatifard, A. (2006) Chromatin modifications by methylation and ubiquitination. Implications in the regulation of gene expression. Annu. Rev. Biochem. 75, 243-269
-
(2006)
Annu. Rev. Biochem.
, vol.75
, pp. 243-269
-
-
Shilatifard, A.1
-
19
-
-
73349092441
-
Histones, annotating chromatin
-
Campos, E. I., and Reinberg, D. (2009) Histones, annotating chromatin. Annu. Rev. Genet. 43, 559-599
-
(2009)
Annu. Rev. Genet.
, vol.43
, pp. 559-599
-
-
Campos, E.I.1
Reinberg, D.2
-
20
-
-
34249337761
-
Perceptions of epigenetics
-
Bird, A. (2007) Perceptions of epigenetics. Nature 447, 396-398
-
(2007)
Nature
, vol.447
, pp. 396-398
-
-
Bird, A.1
-
21
-
-
64349095390
-
An operational definition of epigenetics
-
Berger, S. L., Kouzarides, T., Shiekhattar, R., and Shilatifard, A. (2009) An operational definition of epigenetics. Genes Dev. 23, 781-783
-
(2009)
Genes Dev.
, vol.23
, pp. 781-783
-
-
Berger, S.L.1
Kouzarides, T.2
Shiekhattar, R.3
Shilatifard, A.4
-
22
-
-
78649922622
-
The chromatin signaling pathway. Diverse mechanisms of recruitment of histone-modifying enzymes and varied biological outcomes
-
Smith, E., and Shilatifard, A. (2010) The chromatin signaling pathway. Diverse mechanisms of recruitment of histone-modifying enzymes and varied biological outcomes. Mol. Cell 40, 689-701
-
(2010)
Mol. Cell
, vol.40
, pp. 689-701
-
-
Smith, E.1
Shilatifard, A.2
-
23
-
-
80053559849
-
Genome-wide analysis distinguishes hyperglycemia regulated epigenetic signatures of primary vascular cells
-
Pirola, L., Balcerczyk, A., Tothill, R. W., Haviv, I., Kaspi, A., Lunke, S., Ziemann, M., Karagiannis, T., Tonna, S., Kowalczyk, A., Beresford-Smith, B., Macintyre, G., Kelong, M., Hongyu, Z., Zhu, J., and El-Osta, A. (2011) Genome-wide analysis distinguishes hyperglycemia regulated epigenetic signatures of primary vascular cells. Genome Res. 21, 1601-1615
-
(2011)
Genome Res.
, vol.21
, pp. 1601-1615
-
-
Pirola, L.1
Balcerczyk, A.2
Tothill, R.W.3
Haviv, I.4
Kaspi, A.5
Lunke, S.6
Ziemann, M.7
Karagiannis, T.8
Tonna, S.9
Kowalczyk, A.10
Beresford-Smith, B.11
Macintyre, G.12
Kelong, M.13
Hongyu, Z.14
Zhu, J.15
El-Osta, A.16
-
24
-
-
2342423022
-
In Vivo Chromatin Remodeling Events Leading to Inflammatory Gene Transcription under Diabetic Conditions
-
DOI 10.1074/jbc.M311786200
-
Miao, F., Gonzalo, I. G., Lanting, L., and Natarajan, R. (2004) In vivo chromatin remodeling events leading to inflammatory gene transcription under diabetic conditions. J. Biol. Chem. 279, 18091-18097 (Pubitemid 38560579)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.17
, pp. 18091-18097
-
-
Miao, F.1
Gonzalo, I.G.2
Lanting, L.3
Natarajan, R.4
-
25
-
-
34250303104
-
Genome-wide analysis of histone lysine methylation variations caused by diabetic conditions in human monocytes
-
DOI 10.1074/jbc.M609446200
-
Miao, F., Wu, X., Zhang, L., Yuan, Y. C., Riggs, A. D., and Natarajan, R. (2007) Genome-wide analysis of histone lysine methylation variations caused by diabetic conditions in human monocytes. J. Biol. Chem. 282, 13854-13863 (Pubitemid 47100501)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.18
, pp. 13854-13863
-
-
Miao, F.1
Wu, X.2
Zhang, L.3
Yuan, Y.-C.4
Riggs, A.D.5
Natarajan, R.6
-
26
-
-
48249127225
-
Epigenetic histone H3 lysine 9 methylation in metabolic memory and inflammatory phenotype of vascular smooth muscle cells in diabetes
-
Villeneuve, L. M., Reddy, M. A., Lanting, L. L., Wang, M., Meng, L., and Natarajan, R. (2008) Epigenetic histone H3 lysine 9 methylation in metabolic memory and inflammatory phenotype of vascular smooth muscle cells in diabetes. Proc. Natl. Acad. Sci. U.S.A. 105, 9047-9052
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 9047-9052
-
-
Villeneuve, L.M.1
Reddy, M.A.2
Lanting, L.L.3
Wang, M.4
Meng, L.5
Natarajan, R.6
-
27
-
-
53349101264
-
Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia
-
El-Osta, A., Brasacchio, D., Yao, D., Pocai, A., Jones, P. L., Roeder, R. G., Cooper, M. E., and Brownlee, M. (2008) Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia. J. Exp. Med. 205, 2409-2417
-
(2008)
J. Exp. Med.
, vol.205
, pp. 2409-2417
-
-
El-Osta, A.1
Brasacchio, D.2
Yao, D.3
Pocai, A.4
Jones, P.L.5
Roeder, R.G.6
Cooper, M.E.7
Brownlee, M.8
-
28
-
-
58149345088
-
Lymphocytes from patients with type 1 diabetes display a distinct profile of chromatin histone H3 lysine 9 dimethylation. An epigenetic study in diabetes
-
Miao, F., Smith, D. D., Zhang, L., Min, A., Feng, W., and Natarajan, R. (2008) Lymphocytes from patients with type 1 diabetes display a distinct profile of chromatin histone H3 lysine 9 dimethylation. An epigenetic study in diabetes. Diabetes 57, 3189-3198
-
(2008)
Diabetes
, vol.57
, pp. 3189-3198
-
-
Miao, F.1
Smith, D.D.2
Zhang, L.3
Min, A.4
Feng, W.5
Natarajan, R.6
-
29
-
-
65549170303
-
Hyperglycemia induces a dynamic cooperativity of histone methylase and demethylase enzymes associated with gene-activating epigenetic marks that coexist on the lysine tail
-
Brasacchio, D., Okabe, J., Tikellis, C., Balcerczyk, A., George, P., Baker, E. K., Calkin, A. C., Brownlee, M., Cooper, M. E., and El-Osta, A. (2009) Hyperglycemia induces a dynamic cooperativity of histone methylase and demethylase enzymes associated with gene-activating epigenetic marks that coexist on the lysine tail. Diabetes 58, 1229-1236
-
(2009)
Diabetes
, vol.58
, pp. 1229-1236
-
-
Brasacchio, D.1
Okabe, J.2
Tikellis, C.3
Balcerczyk, A.4
George, P.5
Baker, E.K.6
Calkin, A.C.7
Brownlee, M.8
Cooper, M.E.9
El-Osta, A.10
-
30
-
-
78649879767
-
Epigenetic histone methylation modulates fibrotic gene expression
-
Sun, G., Reddy, M. A., Yuan, H., Lanting, L., Kato, M., and Natarajan, R. (2010) Epigenetic histone methylation modulates fibrotic gene expression. J. Am. Soc. Nephrol. 12, 2069-2080
-
(2010)
J. Am. Soc. Nephrol.
, vol.12
, pp. 2069-2080
-
-
Sun, G.1
Reddy, M.A.2
Yuan, H.3
Lanting, L.4
Kato, M.5
Natarajan, R.6
-
31
-
-
0034704248
-
Genome-wide location and function of DNA binding proteins
-
DOI 10.1126/science.290.5500.2306
-
Ren, B., Robert, F., Wyrick, J. J., Aparicio, O., Jennings, E. G., Simon, I., Zeitlinger, J., Schreiber, J., Hannett, N., Kanin, E., Volkert, T. L., Wilson, C. J., Bell, S. P., and Young, R. A. (2000) Genome-wide location and function of DNA binding proteins. Science 290, 2306-2309 (Pubitemid 32041573)
-
(2000)
Science
, vol.290
, Issue.5500
, pp. 2306-2309
-
-
Ren, B.1
Robert, F.2
Wyrick, J.J.3
Aparicio, O.4
Jennings, E.G.5
Simon, I.6
Zeitlinger, J.7
Schreiber, J.8
Hannett, N.9
Kanin, E.10
Volkert, T.L.11
Wilson, C.J.12
Bell, S.P.13
Young, R.A.14
-
32
-
-
34249026300
-
High-Resolution Profiling of Histone Methylations in the Human Genome
-
DOI 10.1016/j.cell.2007.05.009, PII S0092867407006009
-
Barski, A., Cuddapah, S., Cui, K., Roh, T. Y., Schones, D. E., Wang, Z., Wei, G., Chepelev, I., and Zhao, K. (2007) High-resolution profiling of histone methylations in the human genome. Cell 129, 823-837 (Pubitemid 46802390)
-
(2007)
Cell
, vol.129
, Issue.4
, pp. 823-837
-
-
Barski, A.1
Cuddapah, S.2
Cui, K.3
Roh, T.-Y.4
Schones, D.E.5
Wang, Z.6
Wei, G.7
Chepelev, I.8
Zhao, K.9
-
33
-
-
77953808473
-
Next-generation genomics. An integrative approach
-
Hawkins, R. D., Hon, G. C., and Ren, B. (2010) Next-generation genomics. An integrative approach. Nat. Rev. Genet 11, 476-486
-
(2010)
Nat. Rev. Genet
, vol.11
, pp. 476-486
-
-
Hawkins, R.D.1
Hon, G.C.2
Ren, B.3
-
34
-
-
67349199566
-
Genome-wide association study and metaanalysis find that over 40 loci affect risk of type 1 diabetes
-
Barrett, J. C., Clayton, D. G., Concannon, P., Akolkar, B., Cooper, J. D., Erlich, H. A., Julier, C., Morahan, G., Nerup, J., Nierras, C., Plagnol, V., Pociot, F., Schuilenburg, H., Smyth, D. J., Stevens, H., Todd, J. A., Walker, N. M., and Rich, S. S. (2009) Genome-wide association study and metaanalysis find that over 40 loci affect risk of type 1 diabetes. Nat. Genet. 41, 703-707
-
(2009)
Nat. Genet.
, vol.41
, pp. 703-707
-
-
Barrett, J.C.1
Clayton, D.G.2
Concannon, P.3
Akolkar, B.4
Cooper, J.D.5
Erlich, H.A.6
Julier, C.7
Morahan, G.8
Nerup, J.9
Nierras, C.10
Plagnol, V.11
Pociot, F.12
Schuilenburg, H.13
Smyth, D.J.14
Stevens, H.15
Todd, J.A.16
Walker, N.M.17
Rich, S.S.18
-
35
-
-
77951776390
-
Genetics, pathogenesis, and clinical interventions in type 1 diabetes
-
Bluestone, J. A., Herold, K., and Eisenbarth, G. (2010) Genetics, pathogenesis, and clinical interventions in type 1 diabetes. Nature 464, 1293-1300
-
(2010)
Nature
, vol.464
, pp. 1293-1300
-
-
Bluestone, J.A.1
Herold, K.2
Eisenbarth, G.3
-
36
-
-
70350015386
-
The human major histocompatibility complex as a paradigm in genomics research
-
Vandiedonck, C., and Knight, J. C. (2009) The human major histocompatibility complex as a paradigm in genomics research. Brief. Funct. Genomics Proteomics 8, 379-394
-
(2009)
Brief. Funct. Genomics Proteomics
, vol.8
, pp. 379-394
-
-
Vandiedonck, C.1
Knight, J.C.2
-
37
-
-
0019412551
-
The major histocompatibility complex in man
-
Dausset, J. (1981) The major histocompatibility complex in man. Science 213, 1469-1474
-
(1981)
Science
, vol.213
, pp. 1469-1474
-
-
Dausset, J.1
-
38
-
-
77958500026
-
Microbial stimulation fully differentiates monocytes to DC-SIGN/CD209(+) dendritic cells for immune T cell areas
-
Cheong, C., Matos, I., Choi, J. H., Dandamudi, D. B., Shrestha, E., Longhi, M. P., Jeffrey, K. L., Anthony, R. M., Kluger, C., Nchinda, G., Koh, H., Rodriguez, A., Idoyaga, J., Pack, M., Velinzon, K., Park, C. G., and Steinman, R. M. (2010) Microbial stimulation fully differentiates monocytes to DC-SIGN/CD209(+) dendritic cells for immune T cell areas. Cell 143, 416-429
-
(2010)
Cell
, vol.143
, pp. 416-429
-
-
Cheong, C.1
Matos, I.2
Choi, J.H.3
Dandamudi, D.B.4
Shrestha, E.5
Longhi, M.P.6
Jeffrey, K.L.7
Anthony, R.M.8
Kluger, C.9
Nchinda, G.10
Koh, H.11
Rodriguez, A.12
Idoyaga, J.13
Pack, M.14
Velinzon, K.15
Park, C.G.16
Steinman, R.M.17
-
39
-
-
33745140886
-
Unbiased location analysis of E2F1-binding sites suggests a widespread role for E2F1 in the human genome
-
Bieda, M., Xu, X., Singer, M. A., Green, R., and Farnham, P. J. (2006) Unbiased location analysis of E2F1-binding sites suggests a widespread role for E2F1 in the human genome. Genome Res. 16, 595-605
-
(2006)
Genome Res.
, vol.16
, pp. 595-605
-
-
Bieda, M.1
Xu, X.2
Singer, M.A.3
Green, R.4
Farnham, P.J.5
-
40
-
-
79951672726
-
Regulation of major histocompatibility complex class II genes
-
Choi, N. M., Majumder, P., and Boss, J. M. (2011) Regulation of major histocompatibility complex class II genes. Curr. Opin Immunol. 23, 81-87
-
(2011)
Curr. Opin Immunol.
, vol.23
, pp. 81-87
-
-
Choi, N.M.1
Majumder, P.2
Boss, J.M.3
-
41
-
-
0034194473
-
CIITA is a transcriptional coactivator that is recruited to MHC class II promoters by multiple synergistic interactions with an enhanceosome complex
-
Masternak, K., Muhlethaler-Mottet, A., Villard, J., Zufferey, M., Steimle, V., and Reith, W. (2000) CIITA is a transcriptional coactivator that is recruited to MHC class II promoters by multiple synergistic interactions with an enhanceosome complex. Genes Dev. 14, 1156-1166 (Pubitemid 30324428)
-
(2000)
Genes and Development
, vol.14
, Issue.9
, pp. 1156-1166
-
-
Masternak, K.1
Muhlethaler-Mottet, A.2
Villard, J.3
Zufferey, M.4
Steimle, V.5
Reith, W.6
-
42
-
-
42249105007
-
The insulator factor CTCF controls MHC class II gene expression and is required for the formation of long-distance chromatin interactions
-
DOI 10.1084/jem.20071843
-
Majumder, P., Gomez, J. A., Chadwick, B. P., and Boss, J. M. (2008) The insulator factor CTCF controls MHC class II gene expression and is required for the formation of long-distance chromatin interactions. J. Exp. Med. 205, 785-798 (Pubitemid 351549878)
-
(2008)
Journal of Experimental Medicine
, vol.205
, Issue.4
, pp. 785-798
-
-
Majumder, P.1
Gomez, J.A.2
Chadwick, B.P.3
Boss, J.M.4
-
43
-
-
77956645612
-
CTCF controls expression and chromatin architecture of the human major histocompatibility complex class II locus
-
Majumder, P., and Boss, J. M. (2010) CTCF controls expression and chromatin architecture of the human major histocompatibility complex class II locus. Mol. Cell. Biol. 30, 4211-4223
-
(2010)
Mol. Cell. Biol.
, vol.30
, pp. 4211-4223
-
-
Majumder, P.1
Boss, J.M.2
-
44
-
-
0344358340
-
Autocrine secretion of tumor necrosis factor under the influence of interferon-γ amplifies HLA-DR gene induction in human monocytes
-
Arenzana-Seisdedos, F., Mogensen, S. C., Vuillier, F., Fiers, W., and Virelizier, J. L. (1988) Autocrine secretion of tumor necrosis factor under the influence of interferon-γ amplifies HLA-DR gene induction in human monocytes. Proc. Natl. Acad. Sci. U.S.A. 85, 6087-6091
-
(1988)
Proc. Natl. Acad. Sci. U.S.A.
, vol.85
, pp. 6087-6091
-
-
Arenzana-Seisdedos, F.1
Mogensen, S.C.2
Vuillier, F.3
Fiers, W.4
Virelizier, J.L.5
-
45
-
-
0037320461
-
Chromatin remodeling and extragenic transcription at the MHC class II locus control region
-
DOI 10.1038/ni883
-
Masternak, K., Peyraud, N., Krawczyk, M., Barras, E., and Reith, W. (2003) Chromatin remodeling and extragenic transcription at the MHC class II locus control region. Nat. Immunol. 4, 132-137 (Pubitemid 36193014)
-
(2003)
Nature Immunology
, vol.4
, Issue.2
, pp. 132-137
-
-
Masternak, K.1
Peyraud, N.2
Krawczyk, M.3
Barras, E.4
Reith, W.5
-
46
-
-
65549104157
-
Histone modifications at human enhancers reflect global cell-type-specific gene expression
-
Heintzman, N. D., Hon, G. C., Hawkins, R. D., Kheradpour, P., Stark, A., Harp, L. F., Ye, Z., Lee, L. K., Stuart, R. K., Ching, C. W., Ching, K. A., Antosiewicz-Bourget, J. E., Liu, H., Zhang, X., Green, R. D., Lobanenkov, V. V., Stewart, R., Thomson, J. A., Crawford, G. E., Kellis, M., and Ren, B. (2009) Histone modifications at human enhancers reflect global cell-type-specific gene expression. Nature 459, 108-112
-
(2009)
Nature
, vol.459
, pp. 108-112
-
-
Heintzman, N.D.1
Hon, G.C.2
Hawkins, R.D.3
Kheradpour, P.4
Stark, A.5
Harp, L.F.6
Ye, Z.7
Lee, L.K.8
Stuart, R.K.9
Ching, C.W.10
Ching, K.A.11
Antosiewicz-Bourget, J.E.12
Liu, H.13
Zhang, X.14
Green, R.D.15
Lobanenkov, V.V.16
Stewart, R.17
Thomson, J.A.18
Crawford, G.E.19
Kellis, M.20
Ren, B.21
more..
-
47
-
-
60149091656
-
ChIP-seq accurately predicts tissue-specific activity of enhancers
-
Visel, A., Blow, M. J., Li, Z., Zhang, T., Akiyama, J. A., Holt, A., Plajzer-Frick, I., Shoukry, M., Wright, C., Chen, F., Afzal, V., Ren, B., Rubin, E. M., and Pennacchio, L. A. (2009) ChIP-seq accurately predicts tissue-specific activity of enhancers. Nature 457, 854-858
-
(2009)
Nature
, vol.457
, pp. 854-858
-
-
Visel, A.1
Blow, M.J.2
Li, Z.3
Zhang, T.4
Akiyama, J.A.5
Holt, A.6
Plajzer-Frick, I.7
Shoukry, M.8
Wright, C.9
Chen, F.10
Afzal, V.11
Ren, B.12
Rubin, E.M.13
Pennacchio, L.A.14
-
48
-
-
0023252262
-
HLA-DQ(β) gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus
-
DOI 10.1038/329599a0
-
Todd, J. A., Bell, J. I., and McDevitt, H. O. (1987) HLA-DQβ gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus. Nature 329, 599-604 (Pubitemid 17140111)
-
(1987)
Nature
, vol.329
, Issue.6140
, pp. 599-604
-
-
Todd, J.A.1
Bell, J.I.2
McDevitt, H.O.3
-
49
-
-
34347341846
-
Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes
-
DOI 10.1038/ng2068, PII NG2068
-
Todd, J. A., Walker, N. M., Cooper, J. D., Smyth, D. J., Downes, K., Plagnol, V., Bailey, R., Nejentsev, S., Field, S. F., Payne, F., Lowe, C. E., Szeszko, J. S., Hafler, J. P., Zeitels, L., Yang, J. H., Vella, A., Nutland, S., Stevens, H. E., Schuilenburg, H., Coleman, G., Maisuria, M., Meadows, W., Smink, L. J., Healy, B., Burren, O. S., Lam, A. A., Ovington, N. R., Allen, J., Adlem, E., Leung, H. T., Wallace, C., Howson, J. M., Guja, C., Ionescu-Tîrgovişte, C., Simmonds, M. J., Heward, J. M., Gough, S. C., Dunger, D. B., Wicker, L. S., and Clayton, D. G. (2007) Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes. Nat. Genet. 39, 857-864 (Pubitemid 47018195)
-
(2007)
Nature Genetics
, vol.39
, Issue.7
, pp. 857-864
-
-
Todd, J.A.1
Walker, N.M.2
Cooper, J.D.3
Smyth, D.J.4
Downes, K.5
Plagnol, V.6
Bailey, R.7
Nejentsev, S.8
Field, S.F.9
Payne, F.10
Lowe, C.E.11
Szeszko, J.S.12
Hafler, J.P.13
Zeitels, L.14
Yang, J.H.M.15
Vella, A.16
Nutland, S.17
Stevens, H.E.18
Schuilenburg, H.19
Coleman, G.20
Maisuria, M.21
Meadows, W.22
Smink, L.J.23
Healy, B.24
Burren, O.S.25
Lam, A.A.C.26
Ovington, N.R.27
Allen, J.28
Adlem, E.29
Leung, H.-T.30
Wallace, C.31
Howson, J.M.M.32
Guja, C.33
Ionescu-Tirgoviste, C.34
Simmonds, M.J.35
Heward, J.M.36
Gough, S.C.L.37
Dunger, D.B.38
Wicker, L.S.39
Clayton, D.G.40
more..
-
50
-
-
56549126625
-
GM-CSF induces STAT5 binding at epigenetic regulatory sites within the Csf2 promoter of nonobese diabetic (NOD) mouse myeloid cells
-
Seydel, F., Garrigan, E., Stutevoss, B., Belkin, N., Makadia, B., Carter, J., Shi, J. D., Davoodi-Semiromi, A., McDuffie, M., and Litherland, S. A. (2008) GM-CSF induces STAT5 binding at epigenetic regulatory sites within the Csf2 promoter of nonobese diabetic (NOD) mouse myeloid cells. J. Autoimmun. 31, 377-384
-
(2008)
J. Autoimmun.
, vol.31
, pp. 377-384
-
-
Seydel, F.1
Garrigan, E.2
Stutevoss, B.3
Belkin, N.4
Makadia, B.5
Carter, J.6
Shi, J.D.7
Davoodi-Semiromi, A.8
McDuffie, M.9
Litherland, S.A.10
|