Pathologic shear triggers shedding of vascular receptors: A novel mechanism for down-regulation of platelet glycoprotein VI in stenosed coronary vessels

Blood

Volumn 119, Issue 18, 2012, Pages 4311-4320

  Al Tamimi, Mohammad ^a   Tan, Chee Wee ^b   Qiao, Jianlin ^a   Pennings, Gabrielle J ^b   Javadzadegan, Ashkan ^c   Yong, Andy S C ^b   Arthur, Jane F ^a   Davis, Amanda K ^d   Jing, Jing ^a   Mu, Fi Tjen ^a   Hamilton, Justin R ^a   Jackson, Shaun P ^a   Ludwig, Andreas ^e   Berndt, Michael C ^f   Ward, Christopher M ^b   Kritharides, Leonard ^b   Andrews, Robert K ^a   Gardiner, Elizabeth E ^a  

^a MONASH UNIVERSITY   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

^c UNIVERSITY OF SYDNEY   (Australia)

^d ALFRED HOSPITAL   (Australia)

^e RWTH AACHEN UNIVERSITY   (Germany)

^f DUBLIN CITY UNIVERSITY   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN VI; METALLOPROTEINASE;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CORONARY ARTERY OBSTRUCTION; DOWN REGULATION; ENZYME ACTIVATION; FEMALE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN SECRETION; SHEAR RATE; SHEAR STRESS; THROMBOCYTE ACTIVATION; THROMBOCYTE RICH PLASMA; THROMBOGENESIS;

EID: 84860803422     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2011-10-386607     Document Type: Article

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