Anti-glycoprotein VI monoclonal antibodies directly aggregate platelets independently of FcγRIIa and induce GPVI ectodomain shedding

Platelets

Volumn 20, Issue 2, 2009, Pages 75-82

  Al Tamimi, Mohammad ^a   Mu, Fi Tjen ^a   Arthur, Jane F ^a   Shen, Yang ^a   Moroi, Masaaki ^b   Berndt, Michael C ^a,c   Andrews, Robert K ^a   Gardiner, Elizabeth E ^a  

^a MONASH UNIVERSITY   (Australia)

^b KURUME UNIVERSITY   (Japan)

^c UNIVERSITY COLLEGE CORK   (Ireland)

Author keywords

Antibodies; Glycoprotein VI; Platelets

Indexed keywords

COLLAGEN; CONVULXIN; FC RECEPTOR IIA; GLYCOPROTEIN VI; IMMUNOGLOBULIN; IMMUNOGLOBULIN F(AB) FRAGMENT; METALLOPROTEINASE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 11A7; MONOCLONAL ANTIBODY 12A5; MONOCLONAL ANTIBODY 12C9; MONOCLONAL ANTIBODY 12E2; MONOCLONAL ANTIBODY 12H1; MONOCLONAL ANTIBODY 1A21; MONOCLONAL ANTIBODY 1G5; MONOCLONAL ANTIBODY 4B8; MONOCLONAL ANTIBODY GLYCOPROTEIN VI; UNCLASSIFIED DRUG;

ARTICLE; CELL LYSATE; CONTROLLED STUDY; HUMAN; HUMAN CELL; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN DOMAIN; THROMBOCYTE AGGREGATION; THROMBOCYTE AGGREGATION INHIBITION; THROMBOCYTE RICH PLASMA; WESTERN BLOTTING;

ANIMALS; ANTIBODIES, MONOCLONAL; BLOOD PLATELETS; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; MICE; PLATELET AGGREGATION; PLATELET MEMBRANE GLYCOPROTEINS; RECEPTORS, IGG;

MURINAE;

EID: 61649117544     PISSN: 09537104     EISSN: 13691635     Source Type: Journal    
DOI: 10.1080/09537100802645029     Document Type: Article

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