Crystal structure of a Trypanosoma brucei metacaspase

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 19, 2012, Pages 7469-7474

  McLuskey, Karen ^a   Rudolf, Jana ^a   Proto, William R ^a   Isaacs, Neil W ^b   Coombs, Graham H ^c   Moss, Catherine X ^a   Mottram, Jeremy C ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

^c UNIVERSITY OF STRATHCLYDE   (United Kingdom)

Author keywords

Apoptosis; Clan CD; Parasite; X ray crystallography

Indexed keywords

ARGININE; ASPARTIC ACID; CASPASE; METACASPASE 2; MONOMER; UNCLASSIFIED DRUG;

ALLOSTERISM; AMINO TERMINAL SEQUENCE; ARTICLE; BETA SHEET; CALCIUM BINDING; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; ENZYME STRUCTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN STABILITY; TRYPANOSOMA BRUCEI;

AMINO ACID SEQUENCE; BINDING SITES; BIOCATALYSIS; CALCIUM; CASPASES; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PROTOZOAN PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY; TRYPANOSOMA BRUCEI BRUCEI;

EUKARYOTA; PYRONIA TITHONUS; TRYPANOSOMA BRUCEI;

EID: 84860798287     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1200885109     Document Type: Article

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