Metallothionein expression protects against carbon tetrachloride-induced hepatotoxicity, but overexpression and dietary zinc supplementation provide no further protection in metallothionein transgenic and knockout mice

Journal of Nutrition

Volumn 131, Issue 2, 2001, Pages 215-222

  Davis, Steven R ^a   Samuelson, Don A ^b   Cousins, Robert J ^a,c  

^a Center for Nutritional Sciences   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

^c UNIVERSITY OF FLORIDA   (United States)

Author keywords

Knockout; Metallothionein; Mice; Oxidative stress; Transgenic; Zinc

Indexed keywords

ALANINE AMINOTRANSFERASE; CARBON TETRACHLORIDE; METALLOTHIONEIN; THIOL DERIVATIVE; ZINC;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DIET SUPPLEMENTATION; ENZYME ACTIVITY; FEMALE; GENOTYPE; HISTOLOGY; LIVER PROTECTION; LIVER TOXICITY; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; TRANSGENIC MOUSE;

ANIMALIA; MUS MUSCULUS;

EID: 0035152759     PISSN: 00223166     EISSN: None     Source Type: Journal    
DOI: 10.1093/jn/131.2.215     Document Type: Article

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