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Volumn 27, Issue 6, 2012, Pages 2057-2065

Involvement of ER-α36, Src, EGFR and STAT5 in the biphasic estrogen signaling of ER-negative breast cancer cells

Author keywords

Biphasic response; EGFR; ER 36; ER negative breast cancer cells; Estrogen; Src; STAT5

Indexed keywords

CYCLIN D1; EPIDERMAL GROWTH FACTOR RECEPTOR; ESTROGEN; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR ALPHA36; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN TYROSINE KINASE; STAT5 PROTEIN; UNCLASSIFIED DRUG;

EID: 84860703449     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2012.1722     Document Type: Article
Times cited : (40)

References (38)
  • 2
    • 0035347192 scopus 로고    scopus 로고
    • Rapid actions of plasma membrane estrogen receptors
    • PII S1043276001003770
    • Kelly MJ and Levin ER: Rapid actions of plasma membrane estrogen receptors. Trends Endocrinol Metab 12: 152-156, 2001. (Pubitemid 33713555)
    • (2001) Trends in Endocrinology and Metabolism , vol.12 , Issue.4 , pp. 152-156
    • Kelly, M.J.1    Levin, E.R.2
  • 3
    • 0036780306 scopus 로고    scopus 로고
    • Estrogen action and cytoplasmic signaling cascades. Part I: Membrane-associated signaling complexes
    • DOI 10.1016/S1043-2760(02)00633-1, PII S1043276002006331
    • Segars JH and Driggers PH: Estrogen action and cytoplasmic signaling cascades. Part I: membrane-associated signaling complexes. Trends Endocrinol Metab 13: 349-354, 2002. (Pubitemid 36733951)
    • (2002) Trends in Endocrinology and Metabolism , vol.13 , Issue.8 , pp. 349-354
    • Segars, J.H.1    Driggers, P.H.2
  • 4
    • 25644437706 scopus 로고    scopus 로고
    • Identification, cloning, and expression of human estrogen receptor-α36, a novel variant of human estrogen receptor-α66
    • DOI 10.1016/j.bbrc.2005.08.226, PII S0006291X05019510
    • Wang Z, Zhang X, Shen P, Loggie BW, Chang Y and Deuel TF: Identification, cloning, and expression of human estrogen receptor-α36, a novel variant of human estrogen receptor-α66. Biochem Biophys Res Commun 336: 1023-1027, 2005. (Pubitemid 41383424)
    • (2005) Biochemical and Biophysical Research Communications , vol.336 , Issue.4 , pp. 1023-1027
    • Zhao, Y.W.1    Zhang, X.2    Shen, P.3    Loggie, B.W.4    Chang, Y.5    Deuel, T.F.6
  • 6
    • 64049115275 scopus 로고    scopus 로고
    • Estrogen receptor-alpha (ER-α) suppresses expression of its variant ER-α36
    • Zou Y, Ding L, Coleman M and Wang Z: Estrogen receptor-alpha (ER-α) suppresses expression of its variant ER-α36. FEBS Lett 583: 1368-1374, 2009.
    • (2009) FEBS Lett , vol.583 , pp. 1368-1374
    • Zou, Y.1    Ding, L.2    Coleman, M.3    Wang, Z.4
  • 7
    • 40549117168 scopus 로고    scopus 로고
    • ER-α36, a novel variant of ER-α, is expressed in ER-positive and -negative human breast carcinomas
    • Lee LM, Cao J, Deng H, Chen P, Gatalica Z and Wang ZY: ER-α36, a novel variant of ER-α, is expressed in ER-positive and -negative human breast carcinomas. Anticancer Res 28: 479-483, 2008.
    • (2008) Anticancer Res , vol.28 , pp. 479-483
    • Lee, L.M.1    Cao, J.2    Deng, H.3    Chen, P.4    Gatalica, Z.5    Wang, Z.Y.6
  • 8
    • 69249129572 scopus 로고    scopus 로고
    • Expression of ER-α36, a novel variant of estrogen receptor α, and resistance to tamoxifen treatment in breast cancer
    • Shi L, Dong B, Li Z, et al: Expression of ER-α36, a novel variant of estrogen receptor α, and resistance to tamoxifen treatment in breast cancer. J Clin Oncol 27: 3423-3429, 2009.
    • (2009) J Clin Oncol , vol.27 , pp. 3423-3429
    • Shi, L.1    Dong, B.2    Li, Z.3
  • 9
    • 78650812797 scopus 로고    scopus 로고
    • ER-α36, a novel isoform of ER-α66, is commonly over-expressed in apocrine and adenoid cystic carcinomas of the breast
    • Vranic S, Gatalica Z, Deng H, et al: ER-α36, a novel isoform of ER-α66, is commonly over-expressed in apocrine and adenoid cystic carcinomas of the breast. J Clin Pathol 64: 54-57, 2011.
    • (2011) J Clin Pathol , vol.64 , pp. 54-57
    • Vranic, S.1    Gatalica, Z.2    Deng, H.3
  • 10
    • 79951809981 scopus 로고    scopus 로고
    • A positive feedback loop of ER-α36/EGFR promotes malignant growth of ER-negative breast cancer cells
    • Zhang XT, Kang LG, Ding L, Vranic S, Gatalica Z and Wang ZY: A positive feedback loop of ER-α36/EGFR promotes malignant growth of ER-negative breast cancer cells. Oncogene 30: 770-780, 2011.
    • (2011) Oncogene , vol.30 , pp. 770-780
    • Zhang, X.T.1    Kang, L.G.2    Ding, L.3    Vranic, S.4    Gatalica, Z.5    Wang, Z.Y.6
  • 12
    • 0033036785 scopus 로고    scopus 로고
    • The two phyto-oestrogens genistein and quercetin exert different effects on oestrogen receptor function
    • DOI 10.1038/sj.bjc.6690479
    • Miodini P, Fioravanti L, Di Fronzo G and Cappelletti V: The two phyto-oestrogens genistein and quercetin exert different effects on oestrogen receptor function. Br J Cancer 80: 1150-1155, 1999. (Pubitemid 29264073)
    • (1999) British Journal of Cancer , vol.80 , Issue.8 , pp. 1150-1155
    • Miodini, P.1    Fioravanti, L.2    Di, F.G.3    Cappelletti, V.4
  • 13
    • 34347406512 scopus 로고    scopus 로고
    • Non-monotonic dose-response relationship in steroid hormone receptor-mediated gene expression
    • DOI 10.1677/JME-07-0003
    • Li L, Andersen ME, Heber S and Zhang Q: Non-monotonic dose-response relationship in steroid hormone receptor-mediated gene expression. J Mol Endocrinol 38: 569-585, 2007. (Pubitemid 47019060)
    • (2007) Journal of Molecular Endocrinology , vol.38 , Issue.5-6 , pp. 569-585
    • Li, L.1    Andersen, M.E.2    Heber, S.3    Zhang, Q.4
  • 14
    • 0034895276 scopus 로고    scopus 로고
    • Estrogen and related compounds: Biphasic dose responses
    • Calabrese EJ: Estrogen and related compounds: biphasic dose responses. Crit Rev Toxicol 31: 503-515, 2001.
    • (2001) Crit Rev Toxicol , vol.31 , pp. 503-515
    • Calabrese, E.J.1
  • 15
    • 84964129075 scopus 로고
    • Effects of natural estrogens on L strain fibroblasts in tissue culture
    • Kuchler RJ and Grauer RC: Effects of natural estrogens on L strain fibroblasts in tissue culture. Proc Soc Exp Biol Med 110: 287-292, 1962.
    • (1962) Proc Soc Exp Biol Med , vol.110 , pp. 287-292
    • Kuchler, R.J.1    Grauer, R.C.2
  • 17
    • 0242443868 scopus 로고    scopus 로고
    • Effects of estrogen on cell cycle progression and associated metabolic pathways in normal and tumorigenic breast cells
    • Hass R and Sohn C: Effects of estrogen on cell cycle progression and associated metabolic pathways in normal and tumorigenic breast cells. Signal Transduction 3: 9-16, 2003. (Pubitemid 37392180)
    • (2003) Signal Transduction , vol.3 , Issue.1-2 , pp. 9-16
    • Hass, R.1    Sohn, C.2
  • 18
    • 0014135631 scopus 로고
    • Structural specificity of estrogens in the induction of mitotic chromatid non-disjunction in HeLa cells
    • Rao PN and Engelberg J: Structural specificity of estrogens in the induction of mitotic chromatid non-disjunction in HeLa cells. Exp Cell Res 48: 71-81, 1967.
    • (1967) Exp Cell Res , vol.48 , pp. 71-81
    • Rao, P.N.1    Engelberg, J.2
  • 19
    • 0020524079 scopus 로고
    • Aneuploidy induction and cell transformation by diethylstilbestrol: A possible chromosomal mechanism in carcinogenesis
    • Tsutsui T, Maizumi H, McLachlan JA and Barrett JC: Aneuploidy induction and cell transformation by diethylstilbestrol: a possible chromosomal mechanism in carcinogenesis. Cancer Res 43: 3814-3821, 1983. (Pubitemid 13077710)
    • (1983) Cancer Research , vol.43 , Issue.8 , pp. 3814-3821
    • Tsutsui, T.1    Maizumi, H.2    McLachlan, J.A.3    Barrett, J.C.4
  • 20
    • 79551682463 scopus 로고    scopus 로고
    • Nongenomic signaling pathways of estrogen toxicity
    • Watson CS, Jeng YJ and Kochukov MY: Nongenomic signaling pathways of estrogen toxicity. Toxicol Sci 115: 1-11, 2010.
    • (2010) Toxicol Sci , vol.115 , pp. 1-11
    • Watson, C.S.1    Jeng, Y.J.2    Kochukov, M.Y.3
  • 21
    • 0027357258 scopus 로고
    • A laboratory model to explain the survival advantage observed in patients taking adjuvant tamoxifen therapy
    • Wolf DM and Jordan VC: A laboratory model to explain the survival advantage observed in patients taking adjuvant tamoxifen therapy. Recent Results Cancer Res 127: 23-33, 1993.
    • (1993) Recent Results Cancer Res , vol.127 , pp. 23-33
    • Wolf, D.M.1    Jordan, V.C.2
  • 23
    • 0344742233 scopus 로고    scopus 로고
    • Paradoxical action of fulvestrant in estradiol-induced regression of tamoxifen-stimulated breast cancer
    • Osipo C, Gajdos C, Liu H, Chen B and Jordan VC: Paradoxical action of fulvestrant in estradiol-induced regression of tamoxifen-stimulated breast cancer. J Natl Cancer Inst 95: 1597-1608, 2003. (Pubitemid 37455927)
    • (2003) Journal of the National Cancer Institute , vol.95 , Issue.21 , pp. 1597-1608
    • Osipo, C.1    Gajdos, C.2    Liu, H.3    Chen, B.4    Jordan, V.C.5
  • 25
    • 18144364655 scopus 로고    scopus 로고
    • Estrogen-induced apoptosis in a breast cancer model resistant to long-term estrogen withdrawal
    • DOI 10.1016/j.jsbmb.2004.12.032
    • Lewis JS, Osipo C, Meeke K and Jordan VC: Estrogen-induced apoptosis in a breast cancer model resistant to long-term estrogen withdrawal. J Steroid Biochem Mol Biol 94: 131-141, 2005. (Pubitemid 40614526)
    • (2005) Journal of Steroid Biochemistry and Molecular Biology , vol.94 , Issue.1-3 SPEC. ISS. , pp. 131-141
    • Lewis, J.S.1    Osipo, C.2    Meeke, K.3    Jordan, V.C.4
  • 27
    • 48249132499 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription 5b, c-Src, and epidermal growth factor receptor signaling play integral roles in estrogen-stimulated proliferation of estrogen receptor-positive breast cancer cells
    • Fox EM, Bernaciak TM, Wen J, Weaver AM, Shupnik MA and Silva CM: Signal transducer and activator of transcription 5b, c-Src, and epidermal growth factor receptor signaling play integral roles in estrogen-stimulated proliferation of estrogen receptor-positive breast cancer cells. Mol Endocrinol 22: 1781-1796, 2008.
    • (2008) Mol Endocrinol , vol.22 , pp. 1781-1796
    • Fox, E.M.1    Bernaciak, T.M.2    Wen, J.3    Weaver, A.M.4    Shupnik, M.A.5    Silva, C.M.6
  • 28
    • 0037457078 scopus 로고    scopus 로고
    • Naturally occurring dominant-negative Stat5 suppresses transcriptional activity of estrogen receptors and induces apoptosis in T47D breast cancer cells
    • DOI 10.1038/sj.onc.1206277
    • Yamashita H, Iwase H, Toyama T and Fujii Y: Naturally occurring dominant-negative Stat5 suppresses transcriptional activity of estrogen receptors and induces apoptosis in T47D breast cancer cells. Oncogene 22: 1638-1652, 2003. (Pubitemid 36408179)
    • (2003) Oncogene , vol.22 , Issue.11 , pp. 1638-1652
    • Yamashita, H.1    Iwase, H.2    Toyama, T.3    Fujii, Y.4
  • 29
    • 0036214521 scopus 로고    scopus 로고
    • PRL activates the cyclin D1 promoter via the Jak2/Stat pathway
    • DOI 10.1210/me.16.4.774
    • Brockman JL, Schroeder MD and Schuler LA: PRL activates the cyclin D1 promoter via the Jak2/Stat pathway. Mol Endocrinol 16: 774-784, 2002. (Pubitemid 34297746)
    • (2002) Molecular Endocrinology , vol.16 , Issue.4 , pp. 774-784
    • Brockman, J.L.1    Schroeder, M.D.2    Schuler, L.A.3
  • 30
    • 0026557343 scopus 로고
    • Systemic treatment of early breast cancer by hormonal, cytotoxic, or immune therapy. 133 Randomised trials involving 31,000 recurrences and 24,000 deaths among 75,000 women
    • Early Breast Cancer Trialists' Collaborative Group Early Breast Cancer Trialists' Collaborative Group
    • Early Breast Cancer Trialists' Collaborative Group: Systemic treatment of early breast cancer by hormonal, cytotoxic, or immune therapy. 133 randomised trials involving 31,000 recurrences and 24,000 deaths among 75,000 women. Early Breast Cancer Trialists' Collaborative Group. Lancet 339: 1-15, 1992.
    • (1992) Lancet , vol.339 , pp. 1-15
  • 31
    • 33750971596 scopus 로고
    • 'Prophylactic' ovariectomy and ovarian irradiation in breast cancer
    • Nissen-Meyer R: 'Prophylactic' ovariectomy and ovarian irradiation in breast cancer. Acta Unio Int Contra Cancrum 20: 527-530, 1964.
    • (1964) Acta Unio Int Contra Cancrum , vol.20 , pp. 527-530
    • Nissen-Meyer, R.1
  • 32
    • 0035680432 scopus 로고    scopus 로고
    • Hormonal prevention of hereditary breast cancer
    • Narod SA: Hormonal prevention of hereditary breast cancer. Ann NY Acad Sci 952: 36-43, 2001.
    • (2001) Ann NY Acad Sci , vol.952 , pp. 36-43
    • Narod, S.A.1
  • 34
    • 0035576805 scopus 로고    scopus 로고
    • Akt activation by estrogen in estrogen receptor-negative breast cancer cells
    • Tsai EM, Wang SC, Lee JN and Hung MC: Akt activation by estrogen in estrogen receptor-negative breast cancer cells. Cancer Res 61: 8390-8392, 2001.
    • (2001) Cancer Res , vol.61 , pp. 8390-8392
    • Tsai, E.M.1    Wang, S.C.2    Lee, J.N.3    Hung, M.C.4
  • 35
    • 0028027881 scopus 로고
    • Oestradiol stimulates growth of oestrogen receptor-negative MDA-MB-231 breast cancer cells in immunodeficient mice by reducing cell loss
    • DOI 10.1016/0959-8049(94)00293-E
    • Friedl A and Jordan VC: Oestradiol stimulates growth of oestrogen receptor-negative MDA-MB-231 breast cancer cells in immunodeficient mice by reducing cell loss. Eur J Cancer 30A: 1559-1564, 1994. (Pubitemid 24343022)
    • (1994) European Journal of Cancer Part A: General Topics , vol.30 , Issue.10 , pp. 1559-1564
    • Friedl, A.1    Jordan, V.C.2
  • 36
    • 0036635944 scopus 로고    scopus 로고
    • Oestrogen causes G2/M arrest and apoptosis in breast cancer cells MDA-MB-231
    • Nomoto S, Arao Y, Horiguchi H, Ikeda K and Kayama F: Oestrogen causes G2/M arrest and apoptosis in breast cancer cells MDA-MB-231. Oncol Rep 9: 773-776, 2002.
    • (2002) Oncol Rep , vol.9 , pp. 773-776
    • Nomoto, S.1    Arao, Y.2    Horiguchi, H.3    Ikeda, K.4    Kayama, F.5
  • 37
    • 32144460477 scopus 로고    scopus 로고
    • C-terminal Src kinase (CSK) and CSK-homologous kinase (CHK) - Endogenous negative regulators of Src-family protein kinases
    • DOI 10.1080/08977190500178877, PII J50771704863817
    • Chong YP, Mulhern TD and Cheng HC: C-terminal Src kinase (CSK) and CSK-homologous kinase (CHK) - endogenous negative regulators of Src-family protein kinases. Growth Factors 23: 233-244, 2005. (Pubitemid 43203054)
    • (2005) Growth Factors , vol.23 , Issue.3 , pp. 233-244
    • Chong, Y.-P.1    Mulhern, T.D.2    Cheng, H.-C.3
  • 38
    • 7944233251 scopus 로고    scopus 로고
    • The interplay between Src and integrins in normal and tumor biology
    • DOI 10.1038/sj.onc.1208080
    • Playford MP and Schaller MD: The interplay between Src and integrins in normal and tumor biology. Oncogene 23: 7928-7946, 2004. (Pubitemid 39468852)
    • (2004) Oncogene , vol.23 , Issue.48 REV. ISS. 7 , pp. 7928-7946
    • Playford, M.P.1    Schaller, M.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.