Effect of dose on cyclosporine-induced suppression of hepatic cytochrome P450 3A2 and 2C11

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 49, Issue 2, 2000, Pages 129-135

  Brunner, Lane J ^a   Werner, Ulrike ^a   Gravenall, Clare E ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

Cyclosporine; Cytochrome P450; Hepatic; Metabolism; Rat

Indexed keywords

CYCLOSPORIN; CYCLOSPORIN A; CYTOCHROME P450; TESTOSTERONE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CATALYSIS; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; ENZYME ANALYSIS; ENZYME REPRESSION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNOSUPPRESSIVE TREATMENT; LIVER; LIVER MICROSOME; MALE; NONHUMAN; PROTEIN EXPRESSION; RAT; WESTERN BLOTTING;

ANIMALS; ARYL HYDROCARBON HYDROXYLASES; BLOTTING, WESTERN; CYCLOSPORINE; CYTOCHROME P-450 ENZYME SYSTEM; DOSE-RESPONSE RELATIONSHIP, DRUG; IMMUNOSUPPRESSIVE AGENTS; MALE; MICROSOMES, LIVER; RATS; RATS, SPRAGUE-DAWLEY; SEX FACTORS; STEROID 16-ALPHA-HYDROXYLASE; STEROID HYDROXYLASES;

EID: 0033999295     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0939-6411(99)00084-3     Document Type: Article

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