Genetic inhibition of solute-linked carrier 39 family transporter 1 ameliorates Aβ pathology in a Drosophila model of Alzheimer's disease

PLoS Genetics

Volumn 8, Issue 4, 2012, Pages

  Lang, Minglin ^a,b,c   Wang, Lei ^a   Fan, Qiangwang ^a   Xiao, Guiran ^a   Wang, Xiaoxi ^a   Zhong, Yi ^a,d   Zhou, Bing ^a  

^a TSINGHUA UNIVERSITY   (China)

^b AGRICULTURAL UNIVERSITY OF HEBEI   (China)

^c KANSAS STATE UNIVERSITY   (United States)

^d Howard Hughes Medical Institute Cold Spring Harbor Laboratory Cold Spring Harbor   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; UNCLASSIFIED DRUG; ZINC; ZINC TRANSPORTER; ZRT IRT LIKE PROTEIN; AMYLOID BETA PROTEIN; CATION TRANSPORT PROTEIN; DROSOPHILA PROTEIN; SLC39A1 PROTEIN, HUMAN; ZIP1 PROTEIN, DROSOPHILA;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COGNITION; CONTROLLED STUDY; DISEASE MODEL; DROSOPHILA; FIBER; GENE OVEREXPRESSION; GENE SILENCING; GENETIC ASSOCIATION; GENETIC MANIPULATION; GENETIC MODEL; GENETIC REGULATION; HOMEOSTASIS; LIFESPAN; NERVE DEGENERATION; NEUROPATHOLOGY; NONHUMAN; PHENOTYPE; PROTEIN EXPRESSION; RNA INTERFERENCE; TRANSGENIC ORGANISM; ZINC METABOLISM; ANIMAL; BRAIN; DROSOPHILA MELANOGASTER; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; PATHOPHYSIOLOGY; SEQUENCE HOMOLOGY; TRANSGENIC ANIMAL;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; ANIMALS, GENETICALLY MODIFIED; BRAIN; CATION TRANSPORT PROTEINS; DISEASE MODELS, ANIMAL; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; GENE EXPRESSION REGULATION; HUMANS; PHENOTYPE; SEQUENCE HOMOLOGY, AMINO ACID; ZINC;

EID: 84860549387     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1002683     Document Type: Article

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