Adenosine-mediated inhibition of 5'-AMP-activated protein kinase and p38 mitogen-activated protein kinase during reperfusion enhances recovery of left ventricular mechanical function

Journal of Molecular and Cellular Cardiology

Volumn 52, Issue 6, 2012, Pages 1308-1318

  Omar, Mohamed A ^a   Verma, Sanam ^a   Clanachan, Alexander S ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Adenosine; AMPK; Glycolysis; P38 MAPK; Reperfusion; Ser Thr protein phosphatase

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; 4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE A; 4 AMINO 7 TERT BUTYL 5 (4 METHYLPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; 6 PHOSPHOFRUCTO 2 KINASE; ADENOSINE; CANTHARIDIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; OKADAIC ACID; SERINE; THREONINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CATALYSIS; CONTROLLED STUDY; DRUG EFFICACY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; GLYCOLYSIS; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE ISCHEMIA; HEART PERFUSION; HEART PROTECTION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; REPERFUSION INJURY; TREATMENT RESPONSE;

ADENOSINE; AMP-ACTIVATED PROTEIN KINASES; ANIMALS; CARDIOTONIC AGENTS; GLYCOGEN; GLYCOLYSIS; MALE; MYOCARDIAL REPERFUSION; MYOCARDIUM; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHOFRUCTOKINASE-1; PHOSPHOFRUCTOKINASE-2; PHOSPHORYLATION; PROTONS; RATS; RATS, SPRAGUE-DAWLEY; VENTRICULAR FUNCTION, LEFT;

RATTUS;

EID: 84860539745     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2012.03.014     Document Type: Article

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