Negative control of TLR3 signaling by TICAM1 down-regulation

American Journal of Respiratory Cell and Molecular Biology

Volumn 46, Issue 5, 2012, Pages 660-667

  Tao, Shasha ^a,b   Zhu, Lingxiang ^b   Lee, Pakkei ^c   Lee, Wai Ming ^d   Knox, Kenneth ^e   Chen, Jie ^a   Di, Yuanpu Peter ^f   Chen, Yin ^b  

^a CHINA MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF ARIZONA   (United States)

^c Hamner Institutes for Health Research   (United States)

^d UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^e UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^f UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

Airway; Desensitization; TICAM1; TLR3; Virus

Indexed keywords

BETA INTERFERON; DOUBLE STRANDED RNA; SMALL INTERFERING RNA; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1;

ADAPTIVE IMMUNITY; ARTICLE; CYTOKINE PRODUCTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; HUMAN TISSUE; INNATE IMMUNITY; POSTTRANSCRIPTIONAL GENE SILENCING; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RECEPTOR DOWN REGULATION; RESPIRATORY EPITHELIUM; RHINOVIRUS INFECTION; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; BASE SEQUENCE; DNA PRIMERS; DOWN-REGULATION; FLOW CYTOMETRY; HUMANS; INTERFERONS; REAL-TIME POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 3;

HUMAN RHINOVIRUS SP.;

EID: 84860520638     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/rcmb.2011-0340OC     Document Type: Article

References (38)

1. Roach JC, Glusman G, Rowen L, Kaur A, Purcell MK, Smith KD, Hood LE, Aderem A. The evolution of vertebrate toll-like receptors. Proc Natl Acad Sci USA 2005;102:9577-9582. (Pubitemid 40981723)
2. Brikos C, O'Neill LAJ. Signalling of toll-like receptors. In: S. Bauer GH, editor. Toll-like receptors (TLRs) and innate immunity. Berlin: Springer; 2008. pp. 21-50.
3. Watters TM, Kenny EF, O'Neill LA. Structure, function and regulation of the Toll/IL-1 receptor adaptor proteins. Immunol Cell Biol 2007;85:411-419. (Pubitemid 47367505)
4. Busse WW, Lemanske RF Jr, Gern JE. Role of viral respiratory infections in asthma and asthma exacerbations. Lancet 2010;376:826-834.
5. Varkey JB, Varkey B. Viral infections in patients with chronic obstructive pulmonary disease. Curr Opin Pulm Med 2008;14:89-94. (Pubitemid 351323157)
6. Lipuma JJ. The changing microbial epidemiology in cystic fibrosis. Clin Microbiol Rev 2010;23:299-323.
7. Vercammen E, Staal J, Beyaert R. Sensing of viral infection and activation of innate immunity by toll-like receptor 3. Clin Microbiol Rev 2008;21:13-25. (Pubitemid 351160008)
8. Boukhvalova MS, Sotomayor TB, Point RC, Pletneva LM, Prince GA, Blanco JC. Activation of interferon response through toll-like receptor 3 impacts viral pathogenesis and pulmonary toll-like receptor expression during respiratory syncytial virus and influenza infections in the cotton rat sigmodon hispidus model. J Interferon Cytokine Res 2010;30:229-242.
9. Guillot L, Le Goffic R, Bloch S, Escriou N, Akira S, Chignard M, Si-Tahar M. Involvement of toll-like receptor 3 in the immune response of lung epithelial cells to double-stranded rna and influenza a virus. J Biol Chem 2005;280:5571-5580. (Pubitemid 40280035)
10. Rudd BD, Smit JJ, Flavell RA, Alexopoulou L, Schaller MA, Gruber A, Berlin AA, Lukacs NW. Deletion of tlr3 alters the pulmonary immune environment and mucus production during respiratory syncytial virus infection. J Immunol 2006;176:1937-1942. (Pubitemid 43134339)
11. Hewson CA, Jardine A, Edwards MR, Laza-Stanca V, Johnston SL. Toll-like receptor 3 is induced by and mediates antiviral activity against rhinovirus infection of human bronchial epithelial cells. J Virol 2005;79:12273-12279. (Pubitemid 41346088)
12. Zhu L, Lee PK, Lee WM, Zhao Y, Yu D, Chen Y. Rhinovirus-induced major airway mucin production involves a novel tlr3-EGFR-dependent pathway. Am J Respir Cell Mol Biol 2009;40:610-619.
13. Wang Q, Nagarkar DR, Bowman ER, Schneider D, Gosangi B, Lei J, Zhao Y, McHenry CL, Burgens RV, Miller DJ, et al. Role of double-stranded RNA pattern recognition receptors in rhinovirus-induced airway epithelial cell responses. J Immunol 2009;183:6989-6997.
14. Slater L, Bartlett NW, Haas JJ, Zhu J, Message SD, Walton RP, Sykes A, Dahdaleh S, Clarke DL, Belvisi MG, et al. Co-ordinated role of tlr3, rig-i and mda5 in the innate response to rhinovirus in bronchial epithelium. PLoS Pathog 2010;6:e1001178.
15. Li K, Foy E, Ferreon JC, Nakamura M, Ferreon AC, Ikeda M, Ray SC, Gale M Jr, Lemon SM. Immune evasion by hepatitis C virus ns3/4a protease-mediated cleavage of the toll-like receptor 3 adaptor protein trif. Proc Natl Acad Sci USA 2005;102:2992-2997. (Pubitemid 40299904)
16. Rebsamen M, Meylan E, Curran J, Tschopp J. The antiviral adaptor proteins cardif and trif are processed and inactivated by caspases. Cell Death Differ 2008;15:1804-1811.
17. Han C, Jin J, Xu S, Liu H, Li N, Cao X. Integrin cd11b negatively regulates tlr-triggered inflammatory responses by activating syk and promoting degradation of myd88 and trif via cbl-b. Nat Immunol 2010;11:734-742.
18. Wang W, Lee WM, Mosser AG, Rueckert RR. Win 52035-dependent human rhinovirus 16: assembly deficiency caused by mutations near the canyon surface. J Virol 1998;72:1210-1218. (Pubitemid 28116905)
19. Chen Y, Zhao YH, Di YP, Wu R. Characterization of human mucin 5b gene expression in airway epithelium and the genomic clone of the amino-terminal and 5′-flanking region. Am J Respir Cell Mol Biol 2001;25:542-553. (Pubitemid 33087104)
20. Wu R, Zhao YH, Chang MM. Growth and differentiation of conducting airway epithelial cells in culture. Eur Respir J 1997;10:2398-2403. (Pubitemid 27479567)
21. Chen Y, Hamati E, Lee PK, Lee WM, Wachi S, Schnurr D, Yagi S, Dolganov G, Boushey H, Avila P, et al. Rhinovirus induces airway epithelial gene expression through double-stranded rna and ifn-dependent pathways. Am J Respir Cell Mol Biol 2006;34:192-203. (Pubitemid 43202466)
22. Kao CY, Chen Y, Thai P, Wachi S, Huang F, Kim C, Harper RW, Wu R. Il-17 markedly up-regulates beta-defensin-2 expression in human airway epithelium via jak and NF-kappaB signaling pathways. J Immunol 2004;173:3482-3491. (Pubitemid 39142059)
23. Oshiumi H, Matsumoto M, Funami K, Akazawa T, Seya T. Ticam-1, an adaptor molecule that participates in toll-like receptor 3-mediated interferon-beta induction. Nat Immunol 2003;4:161-167. (Pubitemid 36193018)
24. Mosser AG, Brockman-Schneider R, Amineva S, Burchell L, Sedgwick JB, Busse WW, Gern JE. Similar frequency of rhinovirus-infectible cells in upper and lower airway epithelium. J Infect Dis 2002;185:734-743. (Pubitemid 34226201)
25. Contoli M, Message SD, Laza-Stanca V, Edwards MR, Wark PA, Bartlett NW, Kebadze T, Mallia P, Stanciu LA, Parker HL, et al. Role of deficient type III interferon-lambda production in asthma exacerbations. Nat Med 2006;12:1023-1026. (Pubitemid 44353382)
26. Wark PA, Johnston SL, Bucchieri F, Powell R, Puddicombe S, Laza-Stanca V, Holgate ST, Davies DE. Asthmatic bronchial epithelial cells have a deficient innate immune response to infection with rhinovirus. J Exp Med 2005;201:937-947. (Pubitemid 40524463)
27. Kobayashi M, Yamamoto M. Molecular mechanisms activating the nrf2-keap1 pathway of antioxidant gene regulation. Antioxid Redox Signal 2005;7:385-394. (Pubitemid 40279806)
28. Liew FY, Xu D, Brint EK, O'Neill LA. Negative regulation of toll-like receptor-mediated immune responses. Nat Rev Immunol 2005;5:446-458. (Pubitemid 40835033)
29. Zhang J, Xu LG, Han KJ, Wei X, Shu HB. Piasy represses trif-induced isre and NF-kappaB activation but not apoptosis. FEBS Lett 2004;570:97-101. (Pubitemid 38900964)
30. Stack J, Haga IR, Schroder M, Bartlett NW, Maloney G, Reading PC, Fitzgerald KA, Smith GL, Bowie AG. Vaccinia virus protein a46r targets multiple toll-like-interleukin-1 receptor adaptors and contributes to virulence. J Exp Med 2005;201:1007-1018. (Pubitemid 40524469)
31. Savolainen C, Blomqvist S, Hovi T. Human rhinoviruses. Paediatr Respir Rev 2003;4:91-98. (Pubitemid 36665476)
32. Luttrell LM. Transmembrane signaling by G protein-coupled receptors. Methods Mol Biol 2006;332:3-49.
33. Goldkorn T, Ravid T, Khan EM. Life and death decisions: ceramide generation and egf receptor trafficking are modulated by oxidative stress. Antioxid Redox Signal 2005;7:119-128. (Pubitemid 40187930)
34. Rostron AJ, Cork DM, Avlonitis VS, Fisher AJ, Dark JH, Kirby JA. Contribution of toll-like receptor activation to lung damage after donor brain death. Transplantation 2010;90:732-739.
35. Didierlaurent A, Goulding J, Patel S, Snelgrove R, Low L, Bebien M, Lawrence T, van Rijt LS, Lambrecht BN, Sirard JC, et al. Sustained desensitization to bacterial toll-like receptor ligands after resolution of respiratory influenza infection. J Exp Med 2008;205:323-329. (Pubitemid 351281598)
36. Kwok SK, Lee JY, Park SH, Cho ML, Min SY, Kim HY, Cho YG. Dysfunctional interferon-alpha production by peripheral plasmacy-toid dendritic cells upon toll-like receptor-9 stimulation in patients with systemic lupus erythematosus. Arthritis Res Ther 2008;10:R29.
37. de Bouteiller O, Merck E, Hasan UA, Hubac S, Benguigui B, Trinchieri G, Bates EE, Caux C. Recognition of double-stranded rna by human toll-like receptor 3 and downstream receptor signaling requires multimerization and an acidic ph. J Biol Chem 2005;280:38133-38145. (Pubitemid 43853708)
38. Brix K. Lysosomal proteases: revival of the sleeping beauty. In: Saftig P, editor. Lysosomes. Georgetown, TX, New York, NY: Landes Bioscience/Eurekah. com; 2005. pp. 259-264.