Tissue engineered human tracheas for in vivo implantation

Biomaterials

Volumn 31, Issue 34, 2010, Pages 8931-8938

  Baiguera, Silvia ^a   Jungebluth, Phillip ^a   Burns, Alan ^b   Mavilia, Carmelo ^c   Haag, Johannes ^a   De Coppi, Paolo ^d   Macchiarini, Paolo ^a  

^a CAREGGI UNIVERSITY HOSPITAL   (Italy)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY OF FLORENCE   (Italy)

^d GREAT ORMOND STREET HOSPITAL   (United Kingdom)

Author keywords

Acellular matrix; Angiogenesis; Decellularization protocol; Human trachea; Mechanical properties; Morphological properties

Indexed keywords

ANGIOGENESIS; DECELLULARIZATION; HUMAN TRACHEA; MATRIX; MORPHOLOGICAL PROPERTIES;

BIOCHEMISTRY; BIOMECHANICS; MOLECULAR BIOLOGY; RADIOACTIVE MATERIALS; TISSUE;

MECHANICAL PROPERTIES;

ADULT; ANGIOGENESIS; ARTICLE; BIOMECHANICS; CELL MIGRATION; FEMALE; HISTOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMPLANTATION; IN VITRO STUDY; IN VIVO STUDY; MALE; MOLECULAR BIOLOGY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; TISSUE ENGINEERING; TRACHEA;

ANIMALS; BIOENGINEERING; BIOLOGICAL ASSAY; BIOMECHANICS; CELL MOVEMENT; CHICKENS; CHORIOALLANTOIC MEMBRANE; ENDOTHELIAL CELLS; EXTRACELLULAR MATRIX; FEMALE; FIBROBLAST GROWTH FACTOR 2; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; NEOVASCULARIZATION, PHYSIOLOGIC; PROSTHESIS IMPLANTATION; TISSUE ENGINEERING; TRACHEA;

EID: 77957309783     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2010.08.005     Document Type: Article

References (39)

1. Bader A., Macchiarini P. Moving towards in situ tracheal regeneration: the bionic tissue engineered transplantation approach. J Cell Mol Med 2010, 10.1111/j.1582-4934.2010.01073.x.
2. News B.B.C. Windpipe transplant success in UK child 2010 June, BBC News, London, UK, Available from. http://news.bbc.co.uk/2/hi/8576493.stm.
3. Conconi M.T., De Coppi P., Di Liddo R., Vigolo S., Zanon G.F., Parnigotto P.P., et al. Tracheal matrices, obtained by a detergent-enzymatic method, support in vitro the adhesion of chondrocytes and tracheal epithelial cells. Transpl Int 2005, 18:727-734.
4. Marzaro M., Vigolo S., Oselladore B., Conconi M.T., Ribatti D., Giuliani S., et al. In vitro and in vivo proposal of an artificial esophagus. J Biomed Mater Res A 2006, 77:795-801.
5. De Coppi P., Bellini S., Conconi M.T., Sabatti M., Simonato E., Gamba P.G., et al. Myoblast-acellular skeletal muscle matrix constructs guarantee a long term repair of experimental full-thickness abdominal wall defects. Tissue Eng 2006, 12:1929-1936.
6. Badylak S.F. The extracellular matrix as a biologic scaffold material. Biomaterials 2007, 28:3587-3593.
7. Conconi M.T., Bellini S., Teoli D., de Coppi P., Ribatti D., Nico B., et al. In vitro and in vivo evaluation of acellular diaphragmatic matrices seeded with muscle precursors cells and coated with VEGF silica gels to repair muscle defect of the diaphragm. J Biomed Mater Res 2009, 89A:304-316.
8. Uriel S., Labay E., Francis-Sedlak M., Moya M.L., Weichselbaum R.R., Ervin N., et al. Extraction and assembly of tissue-derived gels for cell culture and tissue engineering. Tissue Eng Part C Methods 2009, 15:309-321.
9. Gilbert T.W., Sellaro T.L., Badylak S.F. Decellularization of tissues and organs. Biomaterials 2006, 27:3675-3683.
10. Macchiarini P., Walles T., Biancosino C., Mertsching H. First human transplantation of a bioengineered airway tissue. J Thorac Cardiovasc Surg 2004, 128:638-641.
11. Walles T., Giere B., Hofmann M., Schanz J., Hofmann F., Mertsching H., et al. Experimental generation of a tissue-engineered functional and vascularized trachea. J Thorac Cardiovasc Surg 2004, 128:900-906.
12. Conconi M.T., De Coppi P., Bellini S., Zara G., Sabatti M., Marzaro M., et al. Homologous muscle acellular matrix seeded with autologous myoblasts as a tissue-engineering approach to abdominal wall-defect repair. Biomaterials 2005, 26:2567-2574.
13. Jungebluth P., Go T., Asnaghi A., Bellini S., Martorell J., Calore C., et al. Structural and morphological evaluation of a novel enzymatic detergent tissue engineered tracheal tubular matrix. J Thorac Cardiovasc Surg 2009, 138:586-593.
14. Macchiarini P., Jungebluth P., Go T., Asnaghi M.A., Rees L.E., Cogan T.A., et al. Clinical transplantation of a tissue-engineered airway. Lancet 2008, 372:2023-2030.
15. Ribatti D., Conconi M.T., Nico B., Baiguera S., Corsi P., Parnigotto P.P., et al. Angiogenic response induced by acellular brain scaffolds grafted onto the chick embryo chorioallantoic membrane. Brain Res 2003, 989:9-15.
16. Conconi M.T., Nico B., Mangieri D., Tommasini M., di Liddo R., Parnigotto P.P., et al. Angiogenic response induced by acellular aortic matrix in vivo. Anatomical Rec 2004, 281A:1303-1307.
17. Meezan E., Hjelle J.T., Brendel K. A simple, versatile, non disruptive method for the isolation of morphologically and chemically pure basement membranes from several tissues. Life Sci 1975, 17:1721-1732.
18. Ahmadi R., Burns A.J., de Bruijn J.D. Chitosan-based hydrogels do not induce angiogenesis. J Tissue Eng Regen Med 2010, 4:309-315.
19. Keshaw H., Thapar N., Burns A.J., Mordan N., Knowles J.C., Forbes A., et al. Microporous collagen spheres produced via thermally induced phase separation for tissue regeneration. Acta Biomater 2010, 6:1158-1166.
20. Hodde J. Naturally occurring scaffolds for soft tissue repair and regeneration. Tissue Eng 2002, 8:295-308.
21. Brennan E.P., Reing J., Chew D., Myers-Irvin J.M., Young E.J., Badylak S.F. Antibacterial activity within degradation products of biological scaffolds composed of extracellular matrix. Tissue Eng 2006, 12:2949-2955.
22. Teng Z., Ochoa I., Li Z., Lin Y., Rodriguez J.F., Bea J.A., et al. Nonlinear mechanical property of tracheal cartilage: a theoretical and experimental study. J Biomech 2008, 41:1995-2002.
23. Park J.W., Pavcnik D., Uchida B.T., Timmermans H., Corless C.L., Yamakado K., et al. Small intestinal submucosa covered expandable Z stents for treatment of tracheal injury: an experimental pilot study in swine. J Vasc Interv Radiol 2000, 11:1325-1330.
24. Gubbels S.P., Richardson M., Trune D., Bascom D.A., Wax M.K. Tracheal reconstruction with porcine small intestine submucosa in a rabbit model. Otolaryngol Head Neck Surg 2006, 134:1028-1035.
25. Zhang L., Liu Z., Cui P., Zhao D., Chen W. SIS with tissue-cultured allogenic cartilages patch tracheoplasty in a rabbit model for tracheal defect. Acta Otolaryngol 2007, 127:631-636.
26. Gilbert T.W., Gilbert S., Madden M., Reynolds S.D., Badylak S.F. Morphologic assessment of extracellular matrix scaffolds for patch tracheoplasty in a canine model. Ann Thorac Surg 2008, 86:967-974.
27. Brown B.N., Barnes C.A., Kasick R.T., Michel R., Gilbert T.W., Beer-Stolz D., et al. Surface characterization of extracellular matrix scaffolds. Biomaterials 2010, 31:428-437.
28. Behrend M., Kluge E., Von Wasielewski R., Klempnauer J. The mechanical influence of tissue engineering techniques on tracheal strength: an experimental study on sheep trachea. J Invest Surg 2002, 15:227-236.
29. Yang M., Chen C.Z., Wang X.N., Zhu Y.B., Gu Y.J. Favorable effects of the detergent and enzyme extraction method for preparing decellularized bovine pericardium scaffold for tissue engineered heart valves. J Biomed Mater Res B Appl Biomater 2009, 91:354-361.
30. Kalluri R. Basement membranes: structure, assembly and role in tumour angiogenesis. Nat Rev Cancer 2003, 3:422-433.
31. Perry J., Tam S., Zheng K., Sado Y., Dobson H., Jefferson B., et al. Type IV collagen induces podocytic features in bone marrow stromal stem cells in vitro. J Am Soc Nephrol 2006, 17:66-76.
32. LeBleu V.S., Macdonald B., Kalluri R. Structure and function of basement membranes. Exp Biol Med 2007, 232:1121-1129.
33. Asnaghi M.A., Jungebluth P., Raimondi M.T., Dickinson S.C., Rees L.E., Go T., et al. A double-chamber rotating bioreactor for the development of tissue-engineered hollow organs: from concept to clinical trial. Biomaterials 2009, 30:5260-5269.
34. Kolb M., Margetts P.J., Sime P.J., Gauldie J. Proteoglycans decorin and biglycan differentially modulate TGF-beta-mediated fibrotic responses in the lung. Am J Physiol Lung Cell Mol Physiol 2001, 280:L1327-L1334.
35. Kanematsu A., Marui A., Yamamoto S., Ozeki M., Hirano Y., Yamamoto M., et al. Type I collagen can function as a reservoir of basic fibroblast growth factor. J Control Release 2004, 99:281-292.
36. Kanematsu A., Yamamoto S., Ozeki M., Noguchi T., Kanatani I., Ogawa O., et al. Collagenous matrices as release carriers of exogenous growth factors. Biomaterials 2004, 25:4513-4520.
37. Schmidt-Schultz T.H., Schultz M. Intact growth factors are conserved in the extracellular matrix of ancient human bone and teeth: a storehouse for the study of human evolution in health and disease. Biol Chem 2005, 386:767-776.
38. Badylak S.F. The extracellular matrix as a scaffold for tissue reconstruction. Semin Cell Dev Biol 2002, 13:377-383.
39. Carson A.E., Barker T.H. Emerging concepts in engineering extracellular matrix variants for directing cell phenotype. Regen Med 2009, 4:593-600.