메뉴 건너뛰기




Volumn 23, Issue , 2012, Pages 121-134

Hydrostatic pressure acts to stabilise a chondrogenic phenotype in porcine joint tissue derived stem cells

Author keywords

Cartilage; Chondrocytes; Hydrostatic pressure; Infrapatellar fat pad; Stem cells; Synovial membrane; Transforming growth factor (TGF) 3

Indexed keywords

COLLAGEN TYPE 10; GLYCOSAMINOGLYCAN; TRANSCRIPTION FACTOR SOX9; TRANSFORMING GROWTH FACTOR BETA3; SONIC HEDGEHOG PROTEIN;

EID: 84860513830     PISSN: 14732262     EISSN: None     Source Type: Journal    
DOI: 10.22203/eCM.v023a09     Document Type: Article
Times cited : (65)

References (69)
  • 1
    • 0038523896 scopus 로고    scopus 로고
    • Cyclic hydrostatic pressure enhances the chondrogenic phenotype of human mesenchymal progenitor cells differentiated in vitro
    • Angele P, Yoo JU, Smith C, Mansour J, Jepsen KJ, Nerlich M, Johnstone B (2003) Cyclic hydrostatic pressure enhances the chondrogenic phenotype of human mesenchymal progenitor cells differentiated in vitro. J Orthop Res 21: 451-457.
    • (2003) J Orthop Res , vol.21 , pp. 451-457
    • Angele, P.1    Yoo, J.U.2    Smith, C.3    Mansour, J.4    Jepsen, K.J.5    Nerlich, M.6    Johnstone, B.7
  • 2
    • 77956882362 scopus 로고    scopus 로고
    • Oxygen tension differentially regulates the functional properties of cartilaginous tissues engineered from infrapatellar fat pad derived MSCs and articular chondrocytes
    • Buckley CT, Vinardell T, Kelly DJ (2010a) Oxygen tension differentially regulates the functional properties of cartilaginous tissues engineered from infrapatellar fat pad derived MSCs and articular chondrocytes. Osteoarthritis Cartilage 18: 1345-1354.
    • (2010) Osteoarthritis Cartilage , vol.18 , pp. 1345-1354
    • Buckley, C.T.1    Vinardell, T.2    Kelly, D.J.3
  • 3
    • 77549083875 scopus 로고    scopus 로고
    • Functional properties of cartilaginous tissues engineered from infrapatellar fat pad-derived mesenchymal stem cells
    • Buckley CT, Vinardell T, Thorpe SD, Haugh MG, Jones E, McGonagle D, Kelly DJ (2010b) Functional properties of cartilaginous tissues engineered from infrapatellar fat pad-derived mesenchymal stem cells. J Biomech 43: 920-926.
    • (2010) J Biomech , vol.43 , pp. 920-926
    • Buckley, C.T.1    Vinardell, T.2    Thorpe, S.D.3    Haugh, M.G.4    Jones, E.5    McGonagle, D.6    Kelly, D.J.7
  • 4
    • 0031661022 scopus 로고    scopus 로고
    • Articular cartilage: Injuries and potential for healing
    • Buckwalter JA (1998) Articular cartilage: injuries and potential for healing. J Orthop Sports Phys Ther 28: 192-202.
    • (1998) J Orthop Sports Phys Ther , vol.28 , pp. 192-202
    • Buckwalter, J.A.1
  • 7
    • 40149089555 scopus 로고    scopus 로고
    • Wnt and hedgehog signaling pathways in bone development
    • Day TF, Yang Y (2008) Wnt and hedgehog signaling pathways in bone development. J Bone Joint Surg Am 90 Suppl 1: 19-24.
    • (2008) J Bone Joint Surg Am , vol.90 , Issue.SUPPL. 1 , pp. 19-24
    • Day, T.F.1    Yang, Y.2
  • 8
    • 0034881402 scopus 로고    scopus 로고
    • Multipotent mesenchymal stem cells from adult human synovial membrane
    • De Bari C, Dell'Accio F, Tylzanowski P, Luyten FP (2001) Multipotent mesenchymal stem cells from adult human synovial membrane. Arthritis Rheum 44: 1928-1942.
    • (2001) Arthritis Rheum , vol.44 , pp. 1928-1942
    • de Bari, C.1    Dell'Accio, F.2    Tylzanowski, P.3    Luyten, F.P.4
  • 9
    • 0345827521 scopus 로고    scopus 로고
    • Failure of in vitro-differentiated mesenchymal stem cells from the synovial membrane to form ectopic stable cartilage in vivo
    • De Bari C, Dell'Accio F, Luyten FP (2004) Failure of in vitro-differentiated mesenchymal stem cells from the synovial membrane to form ectopic stable cartilage in vivo. Arthritis Rheum 50: 142-150.
    • (2004) Arthritis Rheum , vol.50 , pp. 142-150
    • de Bari, C.1    Dell'Accio, F.2    Luyten, F.P.3
  • 10
    • 60849084882 scopus 로고    scopus 로고
    • Calcification or dedifferentiation: Requirement to lock mesenchymal stem cells in a desired differentiation stage
    • Dickhut A, Pelttari K, Janicki P, Wagner W, Eckstein V, Egermann M, Richter W (2009) Calcification or dedifferentiation: requirement to lock mesenchymal stem cells in a desired differentiation stage. J Cell Physiol 219: 219-226.
    • (2009) J Cell Physiol , vol.219 , pp. 219-226
    • Dickhut, A.1    Pelttari, K.2    Janicki, P.3    Wagner, W.4    Eckstein, V.5    Egermann, M.6    Richter, W.7
  • 12
    • 48649099269 scopus 로고    scopus 로고
    • Synergistic and additive effects of hydrostatic pressure and growth factors on tissue formation
    • Elder BD, Athanasiou KA (2008) Synergistic and additive effects of hydrostatic pressure and growth factors on tissue formation. PLoS One 3: e2341.
    • (2008) PLoS One , vol.3
    • Elder, B.D.1    Athanasiou, K.A.2
  • 13
    • 65549169952 scopus 로고    scopus 로고
    • Hydrostatic pressure in articular cartilage tissue engineering: From chondrocytes to tissue regeneration
    • Elder BD, Athanasiou KA (2009) Hydrostatic pressure in articular cartilage tissue engineering: from chondrocytes to tissue regeneration. Tissue Eng Part B Rev 15: 43-53.
    • (2009) Tissue Eng Part B Rev , vol.15 , pp. 43-53
    • Elder, B.D.1    Athanasiou, K.A.2
  • 15
    • 35548983084 scopus 로고    scopus 로고
    • A comparative assessment of cartilage and joint fat pad as a potential source of cells for autologous therapy development in knee osteoarthritis
    • English A, Jones EA, Corscadden D, Henshaw K, Chapman T, Emery P, McGonagle D (2007) A comparative assessment of cartilage and joint fat pad as a potential source of cells for autologous therapy development in knee osteoarthritis. Rheumatol (Oxford) 46: 1676-1683.
    • (2007) Rheumatol (Oxford) , vol.46 , pp. 1676-1683
    • English, A.1    Jones, E.A.2    Corscadden, D.3    Henshaw, K.4    Chapman, T.5    Emery, P.6    McGonagle, D.7
  • 16
    • 80054771407 scopus 로고    scopus 로고
    • Cartilage matrix formation by bovine mesenchymal stem cells in three-dimensional culture is age-dependent
    • Erickson IE, Van Veen SC, Sengupta S, Kestle SR, Mauck RL (2011) Cartilage matrix formation by bovine mesenchymal stem cells in three-dimensional culture is age-dependent. Clin Orthopaed Rel Res 469: 2744-2753.
    • (2011) Clin Orthopaed Rel Res , vol.469 , pp. 2744-2753
    • Erickson, I.E.1    van Veen, S.C.2    Sengupta, S.3    Kestle, S.R.4    Mauck, R.L.5
  • 17
    • 34250800193 scopus 로고    scopus 로고
    • Differential effects on messenger ribonucleic acid expression by bone marrow-derived human mesenchymal stem cells seeded in agarose constructs due to ramped and steady applications of cyclic hydrostatic pressure
    • Finger AR, Sargent CY, Dulaney KO, Bernacki SH, Loboa EG (2007) Differential effects on messenger ribonucleic acid expression by bone marrow-derived human mesenchymal stem cells seeded in agarose constructs due to ramped and steady applications of cyclic hydrostatic pressure. Tissue Eng 13: 1151-1158.
    • (2007) Tissue Eng , vol.13 , pp. 1151-1158
    • Finger, A.R.1    Sargent, C.Y.2    Dulaney, K.O.3    Bernacki, S.H.4    Loboa, E.G.5
  • 18
    • 79952751937 scopus 로고    scopus 로고
    • State of the art and future perspectives of articular cartilage regeneration: A focus on adipose-derived stem cells and platelet-derived products
    • Hildner F, Albrecht C, Gabriel C, Redl H, van Griensven M (2011) State of the art and future perspectives of articular cartilage regeneration: A focus on adipose-derived stem cells and platelet-derived products. J Tissue Eng Regen Med 5: e36-e51.
    • (2011) J Tissue Eng Regen Med , vol.5
    • Hildner, F.1    Albrecht, C.2    Gabriel, C.3    Redl, H.4    van Griensven, M.5
  • 19
    • 80051795750 scopus 로고    scopus 로고
    • A role for the primary cilium in paracrine signaling between mechanically stimulated osteocytes and mesenchymal stem cells
    • Hoey DA, Kelly DJ, Jacobs CR (2011) A role for the primary cilium in paracrine signaling between mechanically stimulated osteocytes and mesenchymal stem cells. Biochem Biophys Res Commun 412: 182-187.
    • (2011) Biochem Biophys Res Commun , vol.412 , pp. 182-187
    • Hoey, D.A.1    Kelly, D.J.2    Jacobs, C.R.3
  • 20
    • 83555176400 scopus 로고    scopus 로고
    • The mechanics of the primary cilium: An intricate structure with complex function
    • Hoey DA, Downs ME, Jacobs CR (2012) The mechanics of the primary cilium: An intricate structure with complex function. J Biomech 45: 17-26.
    • (2012) J Biomech , vol.45 , pp. 17-26
    • Hoey, D.A.1    Downs, M.E.2    Jacobs, C.R.3
  • 22
    • 0037255426 scopus 로고    scopus 로고
    • Mechanoregulation of human articular chondrocyte aggrecan and type II collagen expression by intermittent hydrostatic pressure in vitro
    • Ikenoue T, Trindade MC, Lee MS, Lin EY, Schurman DJ, Goodman SB, Smith RL (2003) Mechanoregulation of human articular chondrocyte aggrecan and type II collagen expression by intermittent hydrostatic pressure in vitro. J Orthop Res 21: 110-116.
    • (2003) J Orthop Res , vol.21 , pp. 110-116
    • Ikenoue, T.1    Trindade, M.C.2    Lee, M.S.3    Lin, E.Y.4    Schurman, D.J.5    Goodman, S.B.6    Smith, R.L.7
  • 24
    • 1542399101 scopus 로고    scopus 로고
    • Biochemical methods for the analysis of tissue-engineered cartilage
    • Kafienah W, Sims TJ (2004) Biochemical methods for the analysis of tissue-engineered cartilage. Methods Mol Biol 238: 217-230.
    • (2004) Methods Mol Biol , vol.238 , pp. 217-230
    • Kafienah, W.1    Sims, T.J.2
  • 25
    • 77949758125 scopus 로고    scopus 로고
    • The role of mechanical signals in regulating chondrogenesis and osteogenesis of mesenchymal stem cells
    • Kelly DJ, Jacobs CR (2010) The role of mechanical signals in regulating chondrogenesis and osteogenesis of mesenchymal stem cells. Birth Defects Res C Embryo Today 90: 75-85.
    • (2010) Birth Defects Res C Embryo Today , vol.90 , pp. 75-85
    • Kelly, D.J.1    Jacobs, C.R.2
  • 26
    • 1042303583 scopus 로고    scopus 로고
    • Effect of a degraded core on the mechanical behaviour of tissue-engineered cartilage constructs: A poro-elastic finite element analysis
    • Kelly DJ, Prendergast PJ (2004) Effect of a degraded core on the mechanical behaviour of tissue-engineered cartilage constructs: a poro-elastic finite element analysis. Med Biol Eng Comput 42: 9-13.
    • (2004) Med Biol Eng Comput , vol.42 , pp. 9-13
    • Kelly, D.J.1    Prendergast, P.J.2
  • 27
    • 34347206376 scopus 로고    scopus 로고
    • Hypoxic conditions increase hypoxia-inducible transcription factor 2alpha and enhance chondrogenesis in stem cells from the infrapatellar fat pad of osteoarthritis patients
    • Khan WS, Adesida AB, Hardingham TE (2007) Hypoxic conditions increase hypoxia-inducible transcription factor 2alpha and enhance chondrogenesis in stem cells from the infrapatellar fat pad of osteoarthritis patients. Arthritis Res Ther 9: R55.
    • (2007) Arthritis Res Ther , vol.9
    • Khan, W.S.1    Adesida, A.B.2    Hardingham, T.E.3
  • 28
    • 48249127947 scopus 로고    scopus 로고
    • Human infrapatellar fat pad-derived stem cells express the pericyte marker 3G5 and show enhanced chondrogenesis after expansion in fibroblast growth factor-2
    • Khan WS, Tew SR, Adesida AB, Hardingham TE (2008) Human infrapatellar fat pad-derived stem cells express the pericyte marker 3G5 and show enhanced chondrogenesis after expansion in fibroblast growth factor-2. Arthritis Res Ther 10: R74.
    • (2008) Arthritis Res Ther , vol.10
    • Khan, W.S.1    Tew, S.R.2    Adesida, A.B.3    Hardingham, T.E.4
  • 29
    • 0023203154 scopus 로고
    • Weight bearing controls glycosaminoglycan concentration and articular cartilage thickness in the knee joints of young beagle dogs
    • Kiviranta I, Jurvelin J, Tammi M, Saamanen AM, Helminen HJ (1987) Weight bearing controls glycosaminoglycan concentration and articular cartilage thickness in the knee joints of young beagle dogs. Arthritis Rheum 30: 801-809.
    • (1987) Arthritis Rheum , vol.30 , pp. 801-809
    • Kiviranta, I.1    Jurvelin, J.2    Tammi, M.3    Saamanen, A.M.4    Helminen, H.J.5
  • 30
    • 0037171146 scopus 로고    scopus 로고
    • The effects of osmotic and hydrostatic pressures on macromolecular systems
    • Kornblatt JA, Kornblatt MJ (2002) The effects of osmotic and hydrostatic pressures on macromolecular systems. Biochim Biophys Acta 1595: 30-47.
    • (2002) Biochim Biophys Acta , vol.1595 , pp. 30-47
    • Kornblatt, J.A.1    Kornblatt, M.J.2
  • 31
    • 0038687536 scopus 로고    scopus 로고
    • Developmental regulation of the growth plate
    • Kronenberg HM (2003) Developmental regulation of the growth plate. Nature 423: 332-336.
    • (2003) Nature , vol.423 , pp. 332-336
    • Kronenberg, H.M.1
  • 32
    • 77955799439 scopus 로고    scopus 로고
    • Primary cilium-dependent mechanosensing is mediated by adenylyl cyclase 6 and cyclic AMP in bone cells
    • Kwon RY, Temiyasathit S, Tummala P, Quah CC, Jacobs CR (2010) Primary cilium-dependent mechanosensing is mediated by adenylyl cyclase 6 and cyclic AMP in bone cells. FASEB J 24: 2859-2868.
    • (2010) FASEB J , vol.24 , pp. 2859-2868
    • Kwon, R.Y.1    Temiyasathit, S.2    Tummala, P.3    Quah, C.C.4    Jacobs, C.R.5
  • 33
    • 52049101630 scopus 로고    scopus 로고
    • Induction of chondrogenesis and expression of superficial zone protein (SZP)/lubricin by mesenchymal progenitors in the infrapatellar fat pad of the knee joint treated with TGFbeta1 and BMP-7
    • Lee SY, Nakagawa T, Reddi AH (2008) Induction of chondrogenesis and expression of superficial zone protein (SZP)/lubricin by mesenchymal progenitors in the infrapatellar fat pad of the knee joint treated with TGFbeta1 and BMP-7. Biochem Biophys Res Commun 376: 148-153.
    • (2008) Biochem Biophys Res Commun , vol.376 , pp. 148-153
    • Lee, S.Y.1    Nakagawa, T.2    Reddi, A.H.3
  • 34
    • 77955162737 scopus 로고    scopus 로고
    • Mechanical load modulates chondrogenesis of human mesenchymal stem cells through the TGF-beta pathway
    • Li Z, Kupcsik L, Yao SJ, Alini M, Stoddart MJ (2010) Mechanical load modulates chondrogenesis of human mesenchymal stem cells through the TGF-beta pathway. J Cell Mol Med 14:1338-1346.
    • (2010) J Cell Mol Med , vol.14 , pp. 1338-1346
    • Li, Z.1    Kupcsik, L.2    Yao, S.J.3    Alini, M.4    Stoddart, M.J.5
  • 35
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25:402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 36
    • 0035215822 scopus 로고    scopus 로고
    • Mechanobiology of initial pseudarthrosis formation with oblique fractures
    • Loboa EG, Beaupre GS, Carter DR (2001) Mechanobiology of initial pseudarthrosis formation with oblique fractures. J Orthop Res 19:1067-1072.
    • (2001) J Orthop Res , vol.19 , pp. 1067-1072
    • Loboa, E.G.1    Beaupre, G.S.2    Carter, D.R.3
  • 39
    • 79960556902 scopus 로고    scopus 로고
    • The effect of cyclic hydrostatic pressure on the functional development of cartilaginous tissues engineered using bone marrow derived mesenchymal stem cells
    • DOI: 10.1016/j.jmbbm.2011.04.012
    • Meyer EG, Buckley CT, Steward AJ, Kelly DJ (2011) The effect of cyclic hydrostatic pressure on the functional development of cartilaginous tissues engineered using bone marrow derived mesenchymal stem cells. J Mech Behaviour Biomed Mater DOI: 10.1016/j.jmbbm.2011.04.012.
    • (2011) J Mech Behaviour Biomed Mater
    • Meyer, E.G.1    Buckley, C.T.2    Steward, A.J.3    Kelly, D.J.4
  • 40
    • 33750955152 scopus 로고    scopus 로고
    • Dose-and time-dependent effects of cyclic hydrostatic pressure on transforming growth factor-beta3-induced chondrogenesis by adult human mesenchymal stem cells in vitro
    • Miyanishi K, Trindade MC, Lindsey DP, Beaupre GS, Carter DR, Goodman SB, Schurman DJ, Smith RL (2006a) Dose-and time-dependent effects of cyclic hydrostatic pressure on transforming growth factor-beta3-induced chondrogenesis by adult human mesenchymal stem cells in vitro. Tissue Eng 12: 2253-2262.
    • (2006) Tissue Eng , vol.12 , pp. 2253-2262
    • Miyanishi, K.1    Trindade, M.C.2    Lindsey, D.P.3    Beaupre, G.S.4    Carter, D.R.5    Goodman, S.B.6    Schurman, D.J.7    Smith, R.L.8
  • 42
    • 33644896782 scopus 로고    scopus 로고
    • Higher chondrogenic potential of fibrous synovium- and adipose synovium-derived cells compared with subcutaneous fatderived cells: Distinguishing properties of mesenchymal stem cells in humans
    • Mochizuki T, Muneta T, Sakaguchi Y, Nimura A, Yokoyama A, Koga H, Sekiya I (2006) Higher chondrogenic potential of fibrous synovium- and adipose synovium-derived cells compared with subcutaneous fatderived cells: distinguishing properties of mesenchymal stem cells in humans. Arthritis Rheum 54: 843-853.
    • (2006) Arthritis Rheum , vol.54 , pp. 843-853
    • Mochizuki, T.1    Muneta, T.2    Sakaguchi, Y.3    Nimura, A.4    Yokoyama, A.5    Koga, H.6    Sekiya, I.7
  • 43
    • 77951259260 scopus 로고    scopus 로고
    • Developing bones are differentially affected by compromised skeletal muscle formation
    • Nowlan NC, Bourdon C, Dumas G, Tajbakhsh S, Prendergast PJ, Murphy P (2010) Developing bones are differentially affected by compromised skeletal muscle formation. Bone 46: 1275-1285.
    • (2010) Bone , vol.46 , pp. 1275-1285
    • Nowlan, N.C.1    Bourdon, C.2    Dumas, G.3    Tajbakhsh, S.4    Prendergast, P.J.5    Murphy, P.6
  • 44
    • 73349117551 scopus 로고    scopus 로고
    • The effect of hydrostatic pressure on three-dimensional chondroinduction of human adipose-derived stem cells
    • Ogawa R, Mizuno S, Murphy GF, Orgill DP (2009) The effect of hydrostatic pressure on three-dimensional chondroinduction of human adipose-derived stem cells. Tissue Eng Part A 15: 2937-2945.
    • (2009) Tissue Eng Part A , vol.15 , pp. 2937-2945
    • Ogawa, R.1    Mizuno, S.2    Murphy, G.F.3    Orgill, D.P.4
  • 45
    • 0018843805 scopus 로고
    • Joint motion in the absence of normal loading does not maintain normal articular cartilage
    • Palmoski MJ, Colyer RA, Brandt KD (1980) Joint motion in the absence of normal loading does not maintain normal articular cartilage. Arthritis Rheum 23: 325-334.
    • (1980) Arthritis Rheum , vol.23 , pp. 325-334
    • Palmoski, M.J.1    Colyer, R.A.2    Brandt, K.D.3
  • 46
    • 0027321110 scopus 로고
    • Effects of cyclic hydrostatic pressure on proteoglycan synthesis in cultured chondrocytes and articular cartilage explants
    • Parkkinen JJ, Ikonen J, Lammi MJ, Laakkonen J, Tammi M, Helminen HJ (1993) Effects of cyclic hydrostatic pressure on proteoglycan synthesis in cultured chondrocytes and articular cartilage explants. Arch Biochem Biophys 300: 458-465.
    • (1993) Arch Biochem Biophys , vol.300 , pp. 458-465
    • Parkkinen, J.J.1    Ikonen, J.2    Lammi, M.J.3    Laakkonen, J.4    Tammi, M.5    Helminen, H.J.6
  • 47
    • 48849107532 scopus 로고    scopus 로고
    • Engineering of functional cartilage tissue using stem cells from synovial lining: A preliminary study
    • Pei M, He F, Kish VL, Vunjak-Novakovic G (2008a) Engineering of functional cartilage tissue using stem cells from synovial lining: a preliminary study. Clin Orthop Relat Res 466: 1880-1889.
    • (2008) Clin Orthop Relat Res , vol.466 , pp. 1880-1889
    • Pei, M.1    He, F.2    Kish, V.L.3    Vunjak-Novakovic, G.4
  • 48
    • 50949104808 scopus 로고    scopus 로고
    • Synoviumderived stem cell-based chondrogenesis
    • Pei M, He F, Vunjak-Novakovic G (2008b) Synoviumderived stem cell-based chondrogenesis. Differentiation 76: 1044-1056.
    • (2008) Differentiation , vol.76 , pp. 1044-1056
    • Pei, M.1    He, F.2    Vunjak-Novakovic, G.3
  • 49
    • 33750321974 scopus 로고    scopus 로고
    • Premature induction of hypertrophy during in vitro chondrogenesis of human mesenchymal stem cells correlates with calcification and vascular invasion after ectopic transplantation in SCID mice
    • Pelttari K, Winter A, Steck E, Goetzke K, Hennig T, Ochs BG, Aigner T, Richter W (2006) Premature induction of hypertrophy during in vitro chondrogenesis of human mesenchymal stem cells correlates with calcification and vascular invasion after ectopic transplantation in SCID mice. Arthritis Rheum 54: 3254-3266.
    • (2006) Arthritis Rheum , vol.54 , pp. 3254-3266
    • Pelttari, K.1    Winter, A.2    Steck, E.3    Goetzke, K.4    Hennig, T.5    Ochs, B.G.6    Aigner, T.7    Richter, W.8
  • 52
    • 79952232344 scopus 로고    scopus 로고
    • Mechanical influences on morphogenesis of the knee joint revealed through morphological, molecular and computational analysis of immobilised embryos
    • Roddy KA, Prendergast PJ, Murphy P (2011) Mechanical influences on morphogenesis of the knee joint revealed through morphological, molecular and computational analysis of immobilised embryos. PLoS One 6: e17526.
    • (2011) PLoS One , vol.6
    • Roddy, K.A.1    Prendergast, P.J.2    Murphy, P.3
  • 54
    • 63349099190 scopus 로고    scopus 로고
    • Mesenchymal stem cells derived from synovium, meniscus, anterior cruciate ligament, and articular chondrocytes share similar gene expression profiles
    • Segawa Y, Muneta T, Makino H, Nimura A, Mochizuki T, Ju YJ, Ezura Y, Umezawa A, Sekiya I (2009) Mesenchymal stem cells derived from synovium, meniscus, anterior cruciate ligament, and articular chondrocytes share similar gene expression profiles. J Orthopaed Res 27: 435-441.
    • (2009) J Orthopaed Res , vol.27 , pp. 435-441
    • Segawa, Y.1    Muneta, T.2    Makino, H.3    Nimura, A.4    Mochizuki, T.5    Ju, Y.J.6    Ezura, Y.7    Umezawa, A.8    Sekiya, I.9
  • 55
    • 80054742150 scopus 로고    scopus 로고
    • Primary cilia modulate Ihh signal transduction in response to hydrostatic loading of growth plate chondrocytes
    • Shao YY, Wang L, Welter JF, Ballock RT (2011) Primary cilia modulate Ihh signal transduction in response to hydrostatic loading of growth plate chondrocytes. Bone 50: 79-84.
    • (2011) Bone , vol.50 , pp. 79-84
    • Shao, Y.Y.1    Wang, L.2    Welter, J.F.3    Ballock, R.T.4
  • 56
    • 84865549430 scopus 로고    scopus 로고
    • Oxygen tension regulates the osteogenic, chondrogenic and endochondral phenotype of bone marrow derived mesenchymal stem cells
    • in press
    • Sheehy EJ, Buckley CT, Kelly DJ (2011) Oxygen tension regulates the osteogenic, chondrogenic and endochondral phenotype of bone marrow derived mesenchymal stem cells. Biochem Biophys Res Commun, in press.
    • (2011) Biochem Biophys Res Commun
    • Sheehy, E.J.1    Buckley, C.T.2    Kelly, D.J.3
  • 57
    • 70349201370 scopus 로고    scopus 로고
    • Mesenchymal stem cell differentiation in an experimental cartilage defect: Restriction of hypertrophy to bone-close neocartilage
    • Steck E, Fischer J, Lorenz H, Gotterbarm T, Jung M, Richter W (2009) Mesenchymal stem cell differentiation in an experimental cartilage defect: restriction of hypertrophy to bone-close neocartilage. Stem Cells Dev 18: 969-978.
    • (2009) Stem Cells Dev , vol.18 , pp. 969-978
    • Steck, E.1    Fischer, J.2    Lorenz, H.3    Gotterbarm, T.4    Jung, M.5    Richter, W.6
  • 58
    • 58949086236 scopus 로고    scopus 로고
    • Cells and biomaterials in cartilage tissue engineering
    • Stoddart MJ, Grad S, Eglin D, Alini M (2009) Cells and biomaterials in cartilage tissue engineering. Regen Med 4: 81-98.
    • (2009) Regen Med , vol.4 , pp. 81-98
    • Stoddart, M.J.1    Grad, S.2    Eglin, D.3    Alini, M.4
  • 59
    • 0036976086 scopus 로고    scopus 로고
    • Upregulation of aggrecan and type II collagen mRNA expression in bovine chondrocytes by the application of hydrostatic pressure
    • Toyoda T, Seedhom BB, Kirkham J, Bonass WA (2003a) Upregulation of aggrecan and type II collagen mRNA expression in bovine chondrocytes by the application of hydrostatic pressure. Biorheology 40: 79-85.
    • (2003) Biorheology , vol.40 , pp. 79-85
    • Toyoda, T.1    Seedhom, B.B.2    Kirkham, J.3    Bonass, W.A.4
  • 60
    • 0142103961 scopus 로고    scopus 로고
    • Hydrostatic pressure modulates proteoglycan metabolism in chondrocytes seeded in agarose
    • Toyoda T, Seedhom BB, Yao JQ, Kirkham J, Brookes S, Bonass WA (2003b) Hydrostatic pressure modulates proteoglycan metabolism in chondrocytes seeded in agarose. Arthritis Rheum 48: 2865-2872.
    • (2003) Arthritis Rheum , vol.48 , pp. 2865-2872
    • Toyoda, T.1    Seedhom, B.B.2    Yao, J.Q.3    Kirkham, J.4    Brookes, S.5    Bonass, W.A.6
  • 61
    • 26444448444 scopus 로고    scopus 로고
    • Phenotypic changes of adult porcine mesenchymal stem cells induced by prolonged passaging in culture
    • Vacanti V, Kong E, Suzuki G, Sato K, Canty JM, Lee T (2005) Phenotypic changes of adult porcine mesenchymal stem cells induced by prolonged passaging in culture. J Cell Physiol 205: 194-201.
    • (2005) J Cell Physiol , vol.205 , pp. 194-201
    • Vacanti, V.1    Kong, E.2    Suzuki, G.3    Sato, K.4    Canty, J.M.5    Lee, T.6
  • 62
    • 80053145900 scopus 로고    scopus 로고
    • Composition-function relations of cartilaginous tissues engineered from chondrocytes and mesenchymal stem cells isolated from bone marrow and infrapatellar fat pad
    • Vinardell T, Buckley CT, Thorpe SD, Kelly DJ (2011) Composition-function relations of cartilaginous tissues engineered from chondrocytes and mesenchymal stem cells isolated from bone marrow and infrapatellar fat pad. J Tissue Eng Regen Med 5: 673-683.
    • (2011) J Tissue Eng Regen Med , vol.5 , pp. 673-683
    • Vinardell, T.1    Buckley, C.T.2    Thorpe, S.D.3    Kelly, D.J.4
  • 65
    • 0037331189 scopus 로고    scopus 로고
    • Cartilagelike gene expression in differentiated human stem cell spheroids: A comparison of bone marrow-derived and adipose tissue-derived stromal cells
    • Winter A, Breit S, Parsch D, Benz K, Steck E, Hauner H, Weber RM, Ewerbeck V, Richter W (2003) Cartilagelike gene expression in differentiated human stem cell spheroids: a comparison of bone marrow-derived and adipose tissue-derived stromal cells. Arthritis Rheum 48: 418-429.
    • (2003) Arthritis Rheum , vol.48 , pp. 418-429
    • Winter, A.1    Breit, S.2    Parsch, D.3    Benz, K.4    Steck, E.5    Hauner, H.6    Weber, R.M.7    Ewerbeck, V.8    Richter, W.9
  • 66
    • 2442420696 scopus 로고    scopus 로고
    • Passage in monolayer influences the response of chondrocytes to dynamic compression
    • Wiseman M, Bader DL, Reisler T, Lee DA (2004) Passage in monolayer influences the response of chondrocytes to dynamic compression. Biorheology 41: 283-298.
    • (2004) Biorheology , vol.41 , pp. 283-298
    • Wiseman, M.1    Bader, D.L.2    Reisler, T.3    Lee, D.A.4
  • 67
    • 0141750631 scopus 로고    scopus 로고
    • Cyclic tensile strain and cyclic hydrostatic pressure differentially regulate expression of hypertrophic markers in primary chondrocytes
    • Wong M, Siegrist M, Goodwin K (2003) Cyclic tensile strain and cyclic hydrostatic pressure differentially regulate expression of hypertrophic markers in primary chondrocytes. Bone 33: 685-693.
    • (2003) Bone , vol.33 , pp. 685-693
    • Wong, M.1    Siegrist, M.2    Goodwin, K.3
  • 68
    • 38349110476 scopus 로고    scopus 로고
    • Effects of hydrostatic pressure on cytoskeleton and BMP-2, TGF-beta, SOX-9 production in rat temporomandibular synovial fibroblasts
    • Wu MJ, Gu ZY, Sun W (2008) Effects of hydrostatic pressure on cytoskeleton and BMP-2, TGF-beta, SOX-9 production in rat temporomandibular synovial fibroblasts. Osteoarthritis Cartilage 16: 41-47.
    • (2008) Osteoarthritis Cartilage , vol.16 , pp. 41-47
    • Wu, M.J.1    Gu, Z.Y.2    Sun, W.3
  • 69
    • 61949188589 scopus 로고    scopus 로고
    • Effect of TGF beta1, BMP-2 and hydraulic pressure on chondrogenic differentiation of bovine bone marrow mesenchymal stromal cells
    • Zeiter S, Lezuo P, Ito K (2009) Effect of TGF beta1, BMP-2 and hydraulic pressure on chondrogenic differentiation of bovine bone marrow mesenchymal stromal cells. Biorheology 46: 45-55.
    • (2009) Biorheology , vol.46 , pp. 45-55
    • Zeiter, S.1    Lezuo, P.2    Ito, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.