메뉴 건너뛰기




Volumn 412, Issue 1, 2011, Pages 182-187

A role for the primary cilium in paracrine signaling between mechanically stimulated osteocytes and mesenchymal stem cells

Author keywords

Fluid flow; Mesenchymal stem cell; Osteocyte; Paracrine signaling; Primary cilium

Indexed keywords

CYCLOOXYGENASE 2; OSTEOPONTIN;

EID: 80051795750     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.07.072     Document Type: Article
Times cited : (106)

References (30)
  • 1
    • 0032895922 scopus 로고    scopus 로고
    • Mechanotransduction in bone - Role of the lacuno-canalicular network
    • Burger E.H., Klein-Nulend J. Mechanotransduction in bone - Role of the lacuno-canalicular network. FASEB J. 1999, 13(Suppl.):S101-112.
    • (1999) FASEB J. , vol.13 , Issue.SUPPL.
    • Burger, E.H.1    Klein-Nulend, J.2
  • 2
    • 34249657953 scopus 로고    scopus 로고
    • Targeted ablation of osteocytes induces osteoporosis with defective mechanotransduction
    • Tatsumi S., Ishii K., Amizuka N., et al. Targeted ablation of osteocytes induces osteoporosis with defective mechanotransduction. Cell Metab. 2007, 5:464-475.
    • (2007) Cell Metab. , vol.5 , pp. 464-475
    • Tatsumi, S.1    Ishii, K.2    Amizuka, N.3
  • 3
    • 0028807366 scopus 로고
    • Mechanotransduction and the functional response of bone to mechanical strain
    • Duncan R.L., Turner C.H. Mechanotransduction and the functional response of bone to mechanical strain. Calcif. Tissue Int. 1995, 57:344-358.
    • (1995) Calcif. Tissue Int. , vol.57 , pp. 344-358
    • Duncan, R.L.1    Turner, C.H.2
  • 4
    • 0028936512 scopus 로고
    • Sensitivity of osteocytes to biomechanical stress in vitro
    • Klein-Nulend J., Van der Plas A., Semeins C.M., et al. Sensitivity of osteocytes to biomechanical stress in vitro. FASEB J. 1995, 9:441-445.
    • (1995) FASEB J. , vol.9 , pp. 441-445
    • Klein-Nulend, J.1    Van der Plas, A.2    Semeins, C.M.3
  • 5
    • 37449027378 scopus 로고    scopus 로고
    • Osteocytes as mechanosensors in the inhibition of bone resorption due to mechanical loading
    • You L., Temiyasathit S., Lee P., et al. Osteocytes as mechanosensors in the inhibition of bone resorption due to mechanical loading. Bone 2008, 42:172-179.
    • (2008) Bone , vol.42 , pp. 172-179
    • You, L.1    Temiyasathit, S.2    Lee, P.3
  • 6
    • 41949089764 scopus 로고    scopus 로고
    • Mechanical stimulation of bone in vivo reduces osteocyte expression of Sost/sclerostin
    • Robling A.G., Niziolek P.J., Baldridge L.A., et al. Mechanical stimulation of bone in vivo reduces osteocyte expression of Sost/sclerostin. J. Biol. Chem. 2008, 283:5866-5875.
    • (2008) J. Biol. Chem. , vol.283 , pp. 5866-5875
    • Robling, A.G.1    Niziolek, P.J.2    Baldridge, L.A.3
  • 7
    • 1542299031 scopus 로고    scopus 로고
    • Conditioned medium from osteocytes stimulates the proliferation of bone marrow mesenchymal stem cells and their differentiation into osteoblasts
    • Heino T.J., Hentunen T.A., Väänänen H.K. Conditioned medium from osteocytes stimulates the proliferation of bone marrow mesenchymal stem cells and their differentiation into osteoblasts. Exp. Cell Res. 2004, 294:458-468.
    • (2004) Exp. Cell Res. , vol.294 , pp. 458-468
    • Heino, T.J.1    Hentunen, T.A.2    Väänänen, H.K.3
  • 8
    • 35348853189 scopus 로고    scopus 로고
    • Osteocytes subjected to fluid flow inhibit osteoclast formation and bone resorption
    • Tan S.D., De Vries T.J., Kuijpers-Jagtman A.M., et al. Osteocytes subjected to fluid flow inhibit osteoclast formation and bone resorption. Bone 2007, 41:745-751.
    • (2007) Bone , vol.41 , pp. 745-751
    • Tan, S.D.1    De Vries, T.J.2    Kuijpers-Jagtman, A.M.3
  • 9
    • 33747151085 scopus 로고    scopus 로고
    • Osteocytes subjected to pulsating fluid flow regulate osteoblast proliferation and differentiation
    • Vezeridis P.S., Semeins C.M., Chen Q., et al. Osteocytes subjected to pulsating fluid flow regulate osteoblast proliferation and differentiation. Biochem. Biophys. Res. Commun. 2006, 348:1082-1088.
    • (2006) Biochem. Biophys. Res. Commun. , vol.348 , pp. 1082-1088
    • Vezeridis, P.S.1    Semeins, C.M.2    Chen, Q.3
  • 10
    • 33846284505 scopus 로고    scopus 로고
    • Mechanically stimulated osteocytes regulate osteoblastic activity via gap junctions
    • Taylor A.F., Saunders M.M., Shingle D.L., et al. Mechanically stimulated osteocytes regulate osteoblastic activity via gap junctions. Am. J. Physiol. - Cell Physiol. 2007, 292.
    • (2007) Am. J. Physiol. - Cell Physiol. , vol.292
    • Taylor, A.F.1    Saunders, M.M.2    Shingle, D.L.3
  • 11
    • 79960145471 scopus 로고    scopus 로고
    • Primary Cilia-Mediated Mechanotransduction in Bone, Clin.
    • Rev. Bone Miner. Metab. (2010) doi: 10.1007/s12018-010-9078-y.
    • K.L. Lee, D.A. Hoey, C.R. Jacobs, Primary Cilia-Mediated Mechanotransduction in Bone, Clin. Rev. Bone Miner. Metab. (2010) doi: 10.1007/s12018-010-9078-y.
    • Lee, K.L.1    Hoey, D.A.2    Jacobs, C.R.3
  • 12
    • 33746891890 scopus 로고    scopus 로고
    • The primary cilium as the cell's antenna: signaling at a sensory organelle
    • Singla V., Reiter J.F. The primary cilium as the cell's antenna: signaling at a sensory organelle. Science 2006, 313:629-633.
    • (2006) Science , vol.313 , pp. 629-633
    • Singla, V.1    Reiter, J.F.2
  • 13
    • 77950673151 scopus 로고    scopus 로고
    • Role of the polycytin-primary cilia complex in bone development and mechanosensing
    • Xiao Z.S., Quarles L.D. Role of the polycytin-primary cilia complex in bone development and mechanosensing. Ann. N. Y. Acad. Sci. 2010, 1192:410-421.
    • (2010) Ann. N. Y. Acad. Sci. , vol.1192 , pp. 410-421
    • Xiao, Z.S.1    Quarles, L.D.2
  • 15
    • 77955799439 scopus 로고    scopus 로고
    • Primary cilium-dependent mechanosensing is mediated by adenylyl cyclase 6 and cyclic AMP in bone cells
    • Kwon R.Y., Temiyasathit S., Tummala P., et al. Primary cilium-dependent mechanosensing is mediated by adenylyl cyclase 6 and cyclic AMP in bone cells. FASEB J. 2010, 24:2859-2868.
    • (2010) FASEB J. , vol.24 , pp. 2859-2868
    • Kwon, R.Y.1    Temiyasathit, S.2    Tummala, P.3
  • 16
    • 34548067953 scopus 로고    scopus 로고
    • Primary cilia mediate mechanosensing in bone cells by a calcium-independent mechanism
    • Malone A.M., Anderson C.T., Tummala P., et al. Primary cilia mediate mechanosensing in bone cells by a calcium-independent mechanism. Proc. Natl. Acad. Sci. USA 2007, 104:13325-13330.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 13325-13330
    • Malone, A.M.1    Anderson, C.T.2    Tummala, P.3
  • 17
    • 78649542978 scopus 로고    scopus 로고
    • Mechanical induction of PGE2 in osteocytes blocks glucocorticoid-induced apoptosis through both the beta-catenin and PKA pathways
    • Kitase Y., Barragan L., Qing H., et al. Mechanical induction of PGE2 in osteocytes blocks glucocorticoid-induced apoptosis through both the beta-catenin and PKA pathways. J. Bone Miner. Res. 2010, 25:2381-2392.
    • (2010) J. Bone Miner. Res. , vol.25 , pp. 2381-2392
    • Kitase, Y.1    Barragan, L.2    Qing, H.3
  • 19
    • 77952582738 scopus 로고    scopus 로고
    • Quantifying fluid shear stress in a rocking culture dish
    • Zhou X., Liu D., You L., Wang L. Quantifying fluid shear stress in a rocking culture dish. J. Biomech. 2010, 43:1598-1602.
    • (2010) J. Biomech. , vol.43 , pp. 1598-1602
    • Zhou, X.1    Liu, D.2    You, L.3    Wang, L.4
  • 20
    • 0035159015 scopus 로고    scopus 로고
    • Polaris, a protein involved in left-right axis patterning, localizes to basal bodies and cilia
    • Taulman P.D., Haycraft C.J., Balkovetz D.F., Yoder B.K. Polaris, a protein involved in left-right axis patterning, localizes to basal bodies and cilia. Mol. Biol. Cell 2001, 12:589-599.
    • (2001) Mol. Biol. Cell , vol.12 , pp. 589-599
    • Taulman, P.D.1    Haycraft, C.J.2    Balkovetz, D.F.3    Yoder, B.K.4
  • 21
    • 7044264360 scopus 로고    scopus 로고
    • Role of osteopontin in adhesion, migration, cell survival and bone remodeling
    • Standal T., Borset M., Sundan A. Role of osteopontin in adhesion, migration, cell survival and bone remodeling. Exp. Oncol. 2004, 26:179-184.
    • (2004) Exp. Oncol. , vol.26 , pp. 179-184
    • Standal, T.1    Borset, M.2    Sundan, A.3
  • 22
    • 0028950225 scopus 로고
    • Rat tail suspension reduces messenger RNA level for growth factors and osteopontin and decreases the osteoblastic differentiation of bone marrow stromal cells
    • Zhang R., Supowit S.C., Klein G.L., et al. Rat tail suspension reduces messenger RNA level for growth factors and osteopontin and decreases the osteoblastic differentiation of bone marrow stromal cells. J. Bone Miner. Res. 1995, 10:415-423.
    • (1995) J. Bone Miner. Res. , vol.10 , pp. 415-423
    • Zhang, R.1    Supowit, S.C.2    Klein, G.L.3
  • 23
    • 37549017616 scopus 로고    scopus 로고
    • Hypoxic osteocytes recruit human MSCs through an OPN/CD44-mediated pathway
    • Raheja L.F., Genetos D.C., Yellowley C.E. Hypoxic osteocytes recruit human MSCs through an OPN/CD44-mediated pathway. Biochem. Biophys. Res. Commun. 2008, 366:1061-1066.
    • (2008) Biochem. Biophys. Res. Commun. , vol.366 , pp. 1061-1066
    • Raheja, L.F.1    Genetos, D.C.2    Yellowley, C.E.3
  • 24
    • 0036259278 scopus 로고    scopus 로고
    • Cyclooxygenase-2 regulates mesenchymal cell differentiation into the osteoblast lineage and is critically involved in bone repair
    • Zhang X., Schwarz E.M., Young D.A., et al. Cyclooxygenase-2 regulates mesenchymal cell differentiation into the osteoblast lineage and is critically involved in bone repair. J. Clin. Invest. 2002, 109:1405-1415.
    • (2002) J. Clin. Invest. , vol.109 , pp. 1405-1415
    • Zhang, X.1    Schwarz, E.M.2    Young, D.A.3
  • 25
    • 0034746416 scopus 로고    scopus 로고
    • Systemic prostaglandin E2 increases cancellous bone formation and mass in aging rats and stimulates their bone marrow osteogenic capacity in vivo and in vitro
    • Keila S., Kelner A., Weinreb M. Systemic prostaglandin E2 increases cancellous bone formation and mass in aging rats and stimulates their bone marrow osteogenic capacity in vivo and in vitro. J. Endocrinol. 2001, 168:131-139.
    • (2001) J. Endocrinol. , vol.168 , pp. 131-139
    • Keila, S.1    Kelner, A.2    Weinreb, M.3
  • 26
    • 12244313406 scopus 로고    scopus 로고
    • Runx2/Cbfa1 functions: diverse regulation of gene transcription by chromatin remodeling and co-regulatory protein interactions
    • Lian J.B., Stein J.L., Stein G.S., et al. Runx2/Cbfa1 functions: diverse regulation of gene transcription by chromatin remodeling and co-regulatory protein interactions. Connect. Tissue Res. 2003, 44(Suppl 1):141-148.
    • (2003) Connect. Tissue Res. , vol.44 , Issue.SUPPL. 1 , pp. 141-148
    • Lian, J.B.1    Stein, J.L.2    Stein, G.S.3
  • 27
    • 0032483809 scopus 로고    scopus 로고
    • Role of the alpha2-integrin in osteoblast-specific gene expression and activation of the Osf2 transcription factor
    • Xiao G., Wang D., Benson M.D., et al. Role of the alpha2-integrin in osteoblast-specific gene expression and activation of the Osf2 transcription factor. J. Biol. Chem. 1998, 273:32988-32994.
    • (1998) J. Biol. Chem. , vol.273 , pp. 32988-32994
    • Xiao, G.1    Wang, D.2    Benson, M.D.3
  • 28
    • 0037441529 scopus 로고    scopus 로고
    • Regulation of the osteoblast-specific transcription factor, Runx2: responsiveness to multiple signal transduction pathways
    • Franceschi R.T., Xiao G. Regulation of the osteoblast-specific transcription factor, Runx2: responsiveness to multiple signal transduction pathways. J. Cell. Biochem. 2003, 88:446-454.
    • (2003) J. Cell. Biochem. , vol.88 , pp. 446-454
    • Franceschi, R.T.1    Xiao, G.2
  • 29
    • 0031981520 scopus 로고    scopus 로고
    • Recruitment and proliferative responses of osteoblasts after mechanical loading in vivo determined using sustained-release bromodeoxyuridine
    • Turner C.H., Owan I., Alvey T., et al. Recruitment and proliferative responses of osteoblasts after mechanical loading in vivo determined using sustained-release bromodeoxyuridine. Bone 1998, 22:463-469.
    • (1998) Bone , vol.22 , pp. 463-469
    • Turner, C.H.1    Owan, I.2    Alvey, T.3
  • 30
    • 0029998565 scopus 로고    scopus 로고
    • Inducible cyclo-oxygenase (COX-2) mediates the induction of bone formation by mechanical loading in vivo
    • Forwood M.R. Inducible cyclo-oxygenase (COX-2) mediates the induction of bone formation by mechanical loading in vivo. J. Bone Miner. Res. 1996, 11:1688-1693.
    • (1996) J. Bone Miner. Res. , vol.11 , pp. 1688-1693
    • Forwood, M.R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.