SERT and TPH-1 mRNA expression are reduced in irritable bowel syndrome patients regardless of visceral sensitivity state in large intestine

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 302, Issue 9, 2012, Pages

  Kerckhoffs, Angèle P M ^a   ter Linde, José J M ^a   Akkermans, Louis M A ^a   Samsom, Melvin ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

5 HT; Par 2; Trypsin IV; Visceral hypersensitivity

Indexed keywords

MESSENGER RNA; SEROTONIN; SEROTONIN REUPTAKE TRANSPORTER; SEROTONIN TRANSPORTER; SUBSTANCE P; TRYPTOPHAN HYDROXYLASE; TRYPTOPHAN HYDROXYLASE 1; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CLINICAL ARTICLE; COLON BIOPSY; CONTROLLED STUDY; DIGESTIVE TRACT PARAMETERS; ENTEROCHROMAFFIN CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IRRITABLE COLON; LARGE INTESTINE; LYMPHOCYTE; MALE; PRIORITY JOURNAL; RECTAL VISCERAL SENSITIVITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADULT; AGED; DOWN-REGULATION; HUMANS; INTESTINE, LARGE; IRRITABLE BOWEL SYNDROME; MIDDLE AGED; RECEPTOR, PAR-2; RNA, MESSENGER; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; TRYPTOPHAN HYDROXYLASE; VISCERAL PAIN; YOUNG ADULT;

EID: 84860503881     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00153.2011     Document Type: Article

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