The post-illumination pupil response of melanopsin-expressing intrinsically photosensitive retinal ganglion cells in diabetes

Acta Ophthalmologica

Volumn 90, Issue 3, 2012, Pages

  Feigl, Beatrix ^a   Zele, Andrew J ^a   Fader, Samantha M ^a   Howes, Annelisa N ^a   Hughes, Catherine E ^a   Jones, Kris A ^a   Jones, Rawlyn ^a  

^a QUEENSLAND UNIVERSITY OF TECHNOLOGY   (Australia)

Author keywords

diabetes; intrinsically photosensitive retinal ganglion cells; melanopsin; post illumination pupil response; pupil light reflex

Indexed keywords

INSULIN; MELANOPSIN;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DIABETIC RETINOPATHY; DISEASE COURSE; DISEASE DURATION; FEMALE; HUMAN; ILLUMINATION; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; OPTICAL COHERENCE TOMOGRAPHY; PHOTORECEPTOR; PHOTOSENSITIVITY; PRIORITY JOURNAL; PUPIL REFLEX; PUPILLOMETER; RETINA DEGENERATION; RETINA GANGLION CELL; RETINA NERVE CELL; VISUAL ACUITY;

AGED; DIABETES MELLITUS, TYPE 2; FEMALE; HUMANS; LIGHT; MALE; MIDDLE AGED; PUPIL; REFLEX, PUPILLARY; RETINAL GANGLION CELLS; ROD OPSINS;

EID: 84860496303     PISSN: 1755375X     EISSN: 17553768     Source Type: Journal    
DOI: 10.1111/j.1755-3768.2011.02226.x     Document Type: Article

References (32)

1. Age-Related Eye Disease Study Research Group (2001): The age-related eye disease study system for classifying cataracts from photographs: AREDS report number 4. Am J Ophthalmol 131: 167-175.
2. Aiello LP, Cahill MT, &, Wong JS, (2001): Systemic considerations in the management of diabetic retinopathy. Am J Ophthalmol 132: 760-776. (Pubitemid 33031293)
3. Cabrere Debuc D, &, Somfai GM, (2010): Early detection of retinal thickness changes in diabetes using Optical Coherence Tomography. Med Sci Monit 16: MT15-MT21.
4. Dacey DM, Liao HW, Peterson BB, Robinson FR, Smith VC, Pokorny J, Yau K-W, &, Gamlin PD, (2005): Melanopsin-expressing ganglion cells in primate retina signal colour and irradiance and project to the LGN. Nature 433: 749-754. (Pubitemid 40292984)
5. Duan XR, Lian YB, Friedman D, et al., (2010): Normal macular thickness measurements using optical coherence tomography in healthy eyes of adult Chinese persons: The Handan Eye Study. Ophthalmology 117: 1585-1594.
6. Feigl B, Mattes D, Thomas R, &, Zele AJ, (2011): Intrinisically photosensitive (melanopsin) retinal ganglion cell function in glaucoma. Invest Ophthalmol Vis Sci 52: 4362-4367.
7. Ferrari GL, Marques JL, Gandhi RA, Emery CJ, Tesfaye S, Heller SR, Schneider FK, &, Gamba HR, (2007): An approach to the assessment of diabetic neuropathy based on dynamic pupillometry. Conf Proc IEEE Eng Med Biol Soc 2007: 557-560.
8. Gamlin PDR, Mcdougal DH, Pokorny J, Smith VC, Yau KW, &, Dacey DM, (2007): Human and macaque pupil responses driven by melanopsin-containing retinal ganglion cells. Vision Res 47: 946-954. (Pubitemid 46365788)
9. Gastinger MJ, Kunselman AR, Conboy EE, Bronson SK, &, Barber AJ, (2008): Dendrite remodeling and other abnormalities in the retinal ganglion cells of Ins2 Akita diabetic mice. Invest Ophthalmol Vis Sci 49: 2635-2642.
10. Hansen MS, Sander B, Kawasaki A, BrOnsted AE, Nissen C, &, Lund-Anderson H, (2011): Prior light exposure enhances the pupil response to subsequent short wavelength (blue) light. J Clinic Experiment Ophthalmol 2. [Epub ahead of print].
11. Harrison WW, Bearse MA, Ng JS, Jewell NP, Barez S, Burger D, Schneck M E, &, Adams AJ, (2010): Multifocal Electroretinograms Predict Onset of Diabetic Retinopathy in Adult Patients with Diabetes. Invest Ophthalmol Vis Sci 52: 772-777.
12. Hattar S, Liao HW, Takao M, Berson DM, &, Yau KW, (2002): Melanopsin containing retinal ganglion cells: architecture, projections and intrinsic photosensitivity. Science 295: 1065-1070. (Pubitemid 34132235)
13. Kankipati L, Girkin C A, &, Gamlin PD, (2010): Post-illumination pupil response in subjects without ocular disease. Invest Ophthalmol Vis Sci 51: 2764-2769.
14. Kankipati L, Girkin CA, &, Gamlin PD, (2011): The post-Illumination pupil response is reduced in glaucoma patients. Invest Ophthalmol Vis Sci 52: 2287-2292.
15. Kardon R, Anderson SC, Damarjian TG, Grace EM, Stone E, &, Kawaski A, (2009): Chromatic pupil responses: preferential activiation of melanopsin mediated versus outer photoreceptor-mediated pupil light reflex. Ophthalmology 116: 1564-1573.
16. Kardon R, Anderson SC, Damarjian TG, Grace EM, Stone E, &, Kawasaki A, (2010): Chromatic Pupillometry in Patients with Retinitis Pigmentosa. Ophthalmology 118: 376-381.
17. Kawasaki A, &, Kardon RH, (2007): Intrinsically photosensitive retinal ganglion cells. J Neuroophthalmol 27: 195-204. (Pubitemid 47482592)
18. Kumar S, &, Zhuo L, (2011): Quantitative analysis of pupillary light reflex by real-time autofluorescent imaging in a diabetic mouse model. Exp Eye Res 92: 164-172.
19. La Morgia C, Ross-Cisneros FN, Sadun AA, et al., (2010): Melanopsin retinal ganglion cells are resistant to neurodegeneration in mitochondrial optic neuropathies. Brain 133: 2426-2438.
20. Li RS, Chen BY, Tay DK, Chan HH, Pu ML, &, So KF, (2006): Melanopsin-expressing retinal ganglion cells are more injury-resistant in a chronic ocular hypertension model. Invest Ophthalmol Vis Sci 47: 2951-2958. (Pubitemid 351639771)
21. Markwell EM, Feigl B, &, Zele AJ, (2010): Intrinsically photosensitive melanopsin retinal ganglion cell contributions to the pupillary light reflex and circadian rhythm. Clin Exp Optom 93: 137-149.
22. McDougal DH, &, Gamlin PD, (2010): The influence of intrinsically-photosensitive retinal ganglion cells on the spectral sensitivity and response dynamics of the human pupillary light reflex. Vision Res 50: 72-87.
23. Mure LS, Cornut PL, Rieux C, Drouyer E, Denis P, Gronfier C, &, Cooper HM, (2009): Melanopsin bistability: a fly's eye technology in the human retina. PLoS ONE 4: e5991.
24. Pokorny J, Smith VC, &, Lutze M, (1987): Aging of the human lens. Appl Opt 26: 1437-1440. (Pubitemid 17061406)
25. Seibold LK, Mandava N, &, Kahook MY, (2010): Comparison of retinal nerve fiber layer thickness in normal eyes using time-Domain and Spectra;-Domain Optical Coherence Tomography. Am J Ophthalmol 150: 807-814.
26. Sugimoto M, Sasoh M, Ido M, Wakitani Y, Takahashi C, &, Uji Y, (2005): Detection of early diabetic change with optical coherence tomography in Type 2 Diabetes Mellitus patients without retinopathy. Ophthalmologica 219: 379-385. (Pubitemid 41628301)
27. Tsujimura S, Ukai K, Ohama D, Nuruki A, &, Yunokuchi K, (2010): Contribution of human melanopsin retinal ganglion cells to steady-state pupil responses. Proc Boil Sci 277: 2485-2492.
28. Van De Kraats J, &, Van Norren D, (2007): Optical density of the aging human ocular media in the visible and the UV. J Opt Soc Am A Opt Image Sci Vis 24: 1842-1857.
29. Vujosevic S, Benetti E, Massignan F, Pilotto E, Varano M, Cavarzeran F, Avogaro A, &, Midena E, (2009): Screening for diabetic retinopathy: 1 and 3 nonmydriatic 45-degree digital fundus photographs vs 7 standard early treatment diabetic retinopathy study fields. Am J Ophthalmol 148: 111-118.
30. Wilhelm BJ, (2010): The Eye of the Inner Clock-Pupil Research in a New Light. Klin Monbl Augenheilkd 227: 840-844.
31. Yang Y, Yu Y, &, Yao K, (2006): Pupillary Dysfunction in Type 2 Diabetes Mellitus to Refine the Early Diagnosis of Diabetic Autonomic Neuropathy. Neuro-ophthalmology 30: 17-21.
32. Zele AJ, Feigl B, Smith SS, &, Markwell EM, (2011): The circadian response of intrinsically photosensitive retinal ganglion cells. PLoS ONE 6: e17860.