-
1
-
-
0027958547
-
Evolutionary conservation of components of the protein translocation complex
-
Hartmann, E., Sommer, T., Prehn, S., Gorlich, D., Jentsch, S., and Rapoport, T. A. (1994) Evolutionary conservation of components of the protein translocation complex Nature 367, 654-657
-
(1994)
Nature
, vol.367
, pp. 654-657
-
-
Hartmann, E.1
Sommer, T.2
Prehn, S.3
Gorlich, D.4
Jentsch, S.5
Rapoport, T.A.6
-
2
-
-
0033281074
-
The translocon: A dynamic gateway at the ER membrane
-
Johnson, A. E. and van Waes, M. A. (1999) The translocon: A dynamic gateway at the ER membrane Annu. Rev. Cell Dev. Biol. 15, 799-842
-
(1999)
Annu. Rev. Cell Dev. Biol.
, vol.15
, pp. 799-842
-
-
Johnson, A.E.1
Van Waes, M.A.2
-
3
-
-
0022827170
-
Mechanism of protein translocation across the endoplasmic reticulum membrane
-
Walter, P. and Lingappa, V. R. (1986) Mechanism of protein translocation across the endoplasmic reticulum membrane Annu. Rev. Cell Biol. 2, 499-516
-
(1986)
Annu. Rev. Cell Biol.
, vol.2
, pp. 499-516
-
-
Walter, P.1
Lingappa, V.R.2
-
4
-
-
0035966109
-
NHE6 protein possesses a signal peptide destined for endoplasmic reticulum membrane and localizes in secretory organelles of the cell
-
Miyazaki, E., Sakaguchi, M., Wakabayashi, S., Shigekawa, M., and Mihara, K. (2001) NHE6 protein possesses a signal peptide destined for endoplasmic reticulum membrane and localizes in secretory organelles of the cell J. Biol. Chem. 276, 49221-49227
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 49221-49227
-
-
Miyazaki, E.1
Sakaguchi, M.2
Wakabayashi, S.3
Shigekawa, M.4
Mihara, K.5
-
5
-
-
77950604267
-
Multiple organelle-targeting signals in the N-terminal portion of peroxisomal membrane protein PMP70
-
Iwashita, S., Tsuchida, M., Tsukuda, M., Yamashita, Y., Emi, Y., Kida, Y., Komori, M., Kashiwayama, Y., Imanaka, T., and Sakaguchi, M. (2010) Multiple organelle-targeting signals in the N-terminal portion of peroxisomal membrane protein PMP70 J. Biochem. 147, 581-590
-
(2010)
J. Biochem.
, vol.147
, pp. 581-590
-
-
Iwashita, S.1
Tsuchida, M.2
Tsukuda, M.3
Yamashita, Y.4
Emi, Y.5
Kida, Y.6
Komori, M.7
Kashiwayama, Y.8
Imanaka, T.9
Sakaguchi, M.10
-
6
-
-
0034697967
-
The Sec61p complex mediates the integration of a membrane protein by allowing lipid partitioning of the transmembrane domain
-
Heinrich, S. U., Mothes, W., Brunner, J., and Rapoport, T. A. (2000) The Sec61p complex mediates the integration of a membrane protein by allowing lipid partitioning of the transmembrane domain Cell 102, 233-244
-
(2000)
Cell
, vol.102
, pp. 233-244
-
-
Heinrich, S.U.1
Mothes, W.2
Brunner, J.3
Rapoport, T.A.4
-
7
-
-
0032544614
-
Signal sequence recognition in posttranslational protein transport across the yeast ER membrane
-
Plath, K., Mothes, W., Wilkinson, B. M., Stirling, C. J., and Rapoport, T. A. (1998) Signal sequence recognition in posttranslational protein transport across the yeast ER membrane Cell 94, 795-807
-
(1998)
Cell
, vol.94
, pp. 795-807
-
-
Plath, K.1
Mothes, W.2
Wilkinson, B.M.3
Stirling, C.J.4
Rapoport, T.A.5
-
8
-
-
36749001066
-
Protein translocation across the eukaryotic endoplasmic reticulum and bacterial plasma membranes
-
Rapoport, T. A. (2007) Protein translocation across the eukaryotic endoplasmic reticulum and bacterial plasma membranes Nature 450, 663-669
-
(2007)
Nature
, vol.450
, pp. 663-669
-
-
Rapoport, T.A.1
-
9
-
-
54049151196
-
Conformational transition of Sec machinery inferred from bacterial SecYE structures
-
Tsukazaki, T., Mori, H., Fukai, S., Ishitani, R., Mori, T., Dohmae, N., Perederina, A., Sugita, Y., Vassylyev, D. G., Ito, K., and Nureki, O. (2008) Conformational transition of Sec machinery inferred from bacterial SecYE structures Nature 455, 988-991
-
(2008)
Nature
, vol.455
, pp. 988-991
-
-
Tsukazaki, T.1
Mori, H.2
Fukai, S.3
Ishitani, R.4
Mori, T.5
Dohmae, N.6
Perederina, A.7
Sugita, Y.8
Vassylyev, D.G.9
Ito, K.10
Nureki, O.11
-
10
-
-
0347192985
-
X-ray structure of a protein-conducting channel
-
Van den Berg, B., Clemons, W. M., Jr., Collinson, I., Modis, Y., Hartmann, E., Harrison, S. C., and Rapoport, T. A. (2004) X-ray structure of a protein-conducting channel Nature 427, 36-44
-
(2004)
Nature
, vol.427
, pp. 36-44
-
-
Van Den Berg, B.1
Clemons Jr., W.M.2
Collinson, I.3
Modis, Y.4
Hartmann, E.5
Harrison, S.C.6
Rapoport, T.A.7
-
11
-
-
0030660436
-
Eukaryotic protein secretion
-
Sakaguchi, M. (1997) Eukaryotic protein secretion Curr. Opin. Biotechnol. 8, 595-601
-
(1997)
Curr. Opin. Biotechnol.
, vol.8
, pp. 595-601
-
-
Sakaguchi, M.1
-
12
-
-
0035979713
-
Topogenesis of membrane proteins: Determinants and dynamics
-
Goder, V. and Spiess, M. (2001) Topogenesis of membrane proteins: Determinants and dynamics FEBS Lett. 504, 87-93
-
(2001)
FEBS Lett.
, vol.504
, pp. 87-93
-
-
Goder, V.1
Spiess, M.2
-
13
-
-
33644855546
-
Function of positive charges following signal-anchor sequences during translocation of the N-terminal domain
-
Kida, Y., Morimoto, F., Mihara, K., and Sakaguchi, M. (2006) Function of positive charges following signal-anchor sequences during translocation of the N-terminal domain J. Biol. Chem. 281, 1152-1158
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 1152-1158
-
-
Kida, Y.1
Morimoto, F.2
Mihara, K.3
Sakaguchi, M.4
-
14
-
-
59149104036
-
Signal anchor sequence provides motive force for polypeptide chain translocation through the endoplasmic reticulum membrane
-
Kida, Y., Morimoto, F., and Sakaguchi, M. (2009) Signal anchor sequence provides motive force for polypeptide chain translocation through the endoplasmic reticulum membrane J. Biol. Chem. 284, 2861-2866
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 2861-2866
-
-
Kida, Y.1
Morimoto, F.2
Sakaguchi, M.3
-
15
-
-
76049128995
-
Environmental transition of signal-anchor sequences during membrane insertion via the endoplasmic reticulum translocon
-
Kida, Y., Kume, C., Hirano, M., and Sakaguchi, M. (2010) Environmental transition of signal-anchor sequences during membrane insertion via the endoplasmic reticulum translocon Mol. Biol. Cell 21, 418-429
-
(2010)
Mol. Biol. Cell
, vol.21
, pp. 418-429
-
-
Kida, Y.1
Kume, C.2
Hirano, M.3
Sakaguchi, M.4
-
16
-
-
0025202897
-
Structural requirements for interruption of protein translocation across rough endoplasmic reticulum membrane
-
Kuroiwa, T., Sakaguchi, M., Mihara, K., and Omura, T. (1990) Structural requirements for interruption of protein translocation across rough endoplasmic reticulum membrane J. Biochem. 108, 829-834
-
(1990)
J. Biochem.
, vol.108
, pp. 829-834
-
-
Kuroiwa, T.1
Sakaguchi, M.2
Mihara, K.3
Omura, T.4
-
17
-
-
0025882870
-
Systematic analysis of stop-transfer sequence for microsomal membrane
-
Kuroiwa, T., Sakaguchi, M., Mihara, K., and Omura, T. (1991) Systematic analysis of stop-transfer sequence for microsomal membrane J. Biol. Chem. 266, 9251-9255
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 9251-9255
-
-
Kuroiwa, T.1
Sakaguchi, M.2
Mihara, K.3
Omura, T.4
-
18
-
-
13444262028
-
Recognition of transmembrane helices by the endoplasmic reticulum translocon
-
Hessa, T., Kim, H., Bihlmaier, K., Lundin, C., Boekel, J., Andersson, H., Nilsson, I., White, S. H., and von Heijne, G. (2005) Recognition of transmembrane helices by the endoplasmic reticulum translocon Nature 433, 377-381
-
(2005)
Nature
, vol.433
, pp. 377-381
-
-
Hessa, T.1
Kim, H.2
Bihlmaier, K.3
Lundin, C.4
Boekel, J.5
Andersson, H.6
Nilsson, I.7
White, S.H.8
Von Heijne, G.9
-
19
-
-
57349168025
-
Molecular code for protein insertion in the endoplasmic reticulum membrane is similar for N(in)-C(out) and N(out)-C(in) transmembrane helices
-
Lundin, C., Kim, H., Nilsson, I., White, S. H., and von Heijne, G. (2008) Molecular code for protein insertion in the endoplasmic reticulum membrane is similar for N(in)-C(out) and N(out)-C(in) transmembrane helices Proc. Natl. Acad. Sci. U.S.A. 105, 15702-15707
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 15702-15707
-
-
Lundin, C.1
Kim, H.2
Nilsson, I.3
White, S.H.4
Von Heijne, G.5
-
20
-
-
77953517920
-
Positive charges of translocating polypeptide chain retrieve an upstream marginal hydrophobic segment from the endoplasmic reticulum lumen to the translocon
-
Fujita, H., Kida, Y., Hagiwara, M., Morimoto, F., and Sakaguchi, M. (2010) Positive charges of translocating polypeptide chain retrieve an upstream marginal hydrophobic segment from the endoplasmic reticulum lumen to the translocon Mol. Biol. Cell 21, 2045-2056
-
(2010)
Mol. Biol. Cell
, vol.21
, pp. 2045-2056
-
-
Fujita, H.1
Kida, Y.2
Hagiwara, M.3
Morimoto, F.4
Sakaguchi, M.5
-
21
-
-
79955399910
-
A sugar chain at a specific position in the nascent polypeptide chain induces forward movement during translocation through the translocon
-
Yamagishi, M., Fujita, H., Morimoto, F., Kida, Y., and Sakaguchi, M. (2011) A sugar chain at a specific position in the nascent polypeptide chain induces forward movement during translocation through the translocon J. Biochem. 149, 591-600
-
(2011)
J. Biochem.
, vol.149
, pp. 591-600
-
-
Yamagishi, M.1
Fujita, H.2
Morimoto, F.3
Kida, Y.4
Sakaguchi, M.5
-
22
-
-
84856868697
-
Positive charges on the translocating polypeptide chain arrest movement through the translocon
-
Fujita, H., Yamagishi, M., Kida, Y., and Sakaguchi, M. (2011) Positive charges on the translocating polypeptide chain arrest movement through the translocon J. Cell Sci. 124, 4184-4193
-
(2011)
J. Cell Sci.
, vol.124
, pp. 4184-4193
-
-
Fujita, H.1
Yamagishi, M.2
Kida, Y.3
Sakaguchi, M.4
-
23
-
-
0035834729
-
Inhibition of protein translocation across the endoplasmic reticulum membrane by sterols
-
Nilsson, I., Ohvo-Rekila, H., Slotte, J. P., Johnson, A. E., and von Heijne, G. (2001) Inhibition of protein translocation across the endoplasmic reticulum membrane by sterols J. Biol. Chem. 276, 41748-41754
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 41748-41754
-
-
Nilsson, I.1
Ohvo-Rekila, H.2
Slotte, J.P.3
Johnson, A.E.4
Von Heijne, G.5
-
24
-
-
0036566310
-
A polytopic membrane protein displays a reversible topology dependent on membrane lipid composition
-
Bogdanov, M., Heacock, P. N., and Dowhan, W. (2002) A polytopic membrane protein displays a reversible topology dependent on membrane lipid composition EMBO J. 21, 2107-2116
-
(2002)
EMBO J.
, vol.21
, pp. 2107-2116
-
-
Bogdanov, M.1
Heacock, P.N.2
Dowhan, W.3
-
25
-
-
51649107357
-
To flip or not to flip: Lipid-protein charge interactions are a determinant of final membrane protein topology
-
Bogdanov, M., Xie, J., Heacock, P., and Dowhan, W. (2008) To flip or not to flip: Lipid-protein charge interactions are a determinant of final membrane protein topology J. Cell Biol. 182, 925-935
-
(2008)
J. Cell Biol.
, vol.182
, pp. 925-935
-
-
Bogdanov, M.1
Xie, J.2
Heacock, P.3
Dowhan, W.4
-
26
-
-
0346749514
-
Reversible topological organization within a polytopic membrane protein is governed by a change in membrane phospholipid composition
-
Zhang, W., Bogdanov, M., Pi, J., Pittard, A. J., and Dowhan, W. (2003) Reversible topological organization within a polytopic membrane protein is governed by a change in membrane phospholipid composition J. Biol. Chem. 278, 50128-50135
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 50128-50135
-
-
Zhang, W.1
Bogdanov, M.2
Pi, J.3
Pittard, A.J.4
Dowhan, W.5
-
27
-
-
22544444966
-
Phospholipids as determinants of membrane protein topology. Phosphatidylethanolamine is required for the proper topological organization of the γ-aminobutyric acid permease (GabP) of Escherichia coli
-
Zhang, W., Campbell, H. A., King, S. C., and Dowhan, W. (2005) Phospholipids as determinants of membrane protein topology. Phosphatidylethanolamine is required for the proper topological organization of the γ-aminobutyric acid permease (GabP) of Escherichia coli J. Biol. Chem. 280, 26032-26038
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 26032-26038
-
-
Zhang, W.1
Campbell, H.A.2
King, S.C.3
Dowhan, W.4
-
28
-
-
38049058405
-
Two translocating hydrophilic segments of a nascent chain span the ER membrane during multispanning protein topogenesis
-
Kida, Y., Morimoto, F., and Sakaguchi, M. (2007) Two translocating hydrophilic segments of a nascent chain span the ER membrane during multispanning protein topogenesis J. Cell Biol. 179, 1441-1452
-
(2007)
J. Cell Biol.
, vol.179
, pp. 1441-1452
-
-
Kida, Y.1
Morimoto, F.2
Sakaguchi, M.3
-
29
-
-
0020994721
-
Preparation of microsomal membranes for cotranslational protein translocation
-
Walter, P. and Blobel, G. (1983) Preparation of microsomal membranes for cotranslational protein translocation Methods Enzymol. 96, 84-93
-
(1983)
Methods Enzymol.
, vol.96
, pp. 84-93
-
-
Walter, P.1
Blobel, G.2
-
30
-
-
0021004695
-
Preparation and use of nuclease-treated rabbit reticulocyte lysates for the translation of eukaryotic messenger RNA
-
Jackson, R. J. and Hunt, T. (1983) Preparation and use of nuclease-treated rabbit reticulocyte lysates for the translation of eukaryotic messenger RNA Methods Enzymol. 96, 50-74
-
(1983)
Methods Enzymol.
, vol.96
, pp. 50-74
-
-
Jackson, R.J.1
Hunt, T.2
-
31
-
-
0026675770
-
Mitochondrial porin can be translocated across both endoplasmic reticulum and mitochondrial membranes
-
Sakaguchi, M., Hachiya, N., Mihara, K., and Omura, T. (1992) Mitochondrial porin can be translocated across both endoplasmic reticulum and mitochondrial membranes J. Biochem. 112, 243-248
-
(1992)
J. Biochem.
, vol.112
, pp. 243-248
-
-
Sakaguchi, M.1
Hachiya, N.2
Mihara, K.3
Omura, T.4
-
32
-
-
0030695849
-
Use of cyclodextrins for manipulating cellular cholesterol content
-
Christian, A. E., Haynes, M. P., Phillips, M. C., and Rothblat, G. H. (1997) Use of cyclodextrins for manipulating cellular cholesterol content J. Lipid Res. 38, 2264-2272
-
(1997)
J. Lipid Res.
, vol.38
, pp. 2264-2272
-
-
Christian, A.E.1
Haynes, M.P.2
Phillips, M.C.3
Rothblat, G.H.4
-
33
-
-
0029879111
-
Membrane stiffness and channel function
-
Lundbaek, J. A., Birn, P., Girshman, J., Hansen, A. J., and Andersen, O. S. (1996) Membrane stiffness and channel function Biochemistry 35, 3825-3830
-
(1996)
Biochemistry
, vol.35
, pp. 3825-3830
-
-
Lundbaek, J.A.1
Birn, P.2
Girshman, J.3
Hansen, A.J.4
Andersen, O.S.5
-
34
-
-
23944464223
-
Capsaicin regulates voltage-dependent sodium channels by altering lipid bilayer elasticity
-
Lundbaek, J. A., Birn, P., Tape, S. E., Toombes, G. E., Sogaard, R., Koeppe, R. E., II, Gruner, S. M., Hansen, A. J., and Andersen, O. S. (2005) Capsaicin regulates voltage-dependent sodium channels by altering lipid bilayer elasticity Mol. Pharmacol. 68, 680-689
-
(2005)
Mol. Pharmacol.
, vol.68
, pp. 680-689
-
-
Lundbaek, J.A.1
Birn, P.2
Tape, S.E.3
Toombes, G.E.4
Sogaard, R.5
Koeppe, R.E.I.I.6
Gruner, S.M.7
Hansen, A.J.8
Andersen, O.S.9
-
35
-
-
4344578601
-
Enrichment of endoplasmic reticulum with cholesterol inhibits sarcoplasmic-endoplasmic reticulum calcium ATPase-2b activity in parallel with increased order of membrane lipids: Implications for depletion of endoplasmic reticulum calcium stores and apoptosis in cholesterol-loaded macrophages
-
Li, Y., Ge, M., Ciani, L., Kuriakose, G., Westover, E. J., Dura, M., Covey, D. F., Freed, J. H., Maxfield, F. R., Lytton, J., and Tabas, I. (2004) Enrichment of endoplasmic reticulum with cholesterol inhibits sarcoplasmic-endoplasmic reticulum calcium ATPase-2b activity in parallel with increased order of membrane lipids: Implications for depletion of endoplasmic reticulum calcium stores and apoptosis in cholesterol-loaded macrophages J. Biol. Chem. 279, 37030-37039
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 37030-37039
-
-
Li, Y.1
Ge, M.2
Ciani, L.3
Kuriakose, G.4
Westover, E.J.5
Dura, M.6
Covey, D.F.7
Freed, J.H.8
Maxfield, F.R.9
Lytton, J.10
Tabas, I.11
-
36
-
-
1542313960
-
Sec61p contributes to signal sequence orientation according to the positive-inside rule
-
Goder, V., Junne, T., and Spiess, M. (2004) Sec61p contributes to signal sequence orientation according to the positive-inside rule Mol. Biol. Cell 15, 1470-1478
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 1470-1478
-
-
Goder, V.1
Junne, T.2
Spiess, M.3
-
37
-
-
77952378779
-
The hydrophobic core of the Sec61 translocon defines the hydrophobicity threshold for membrane integration
-
Junne, T., Kocik, L., and Spiess, M. (2010) The hydrophobic core of the Sec61 translocon defines the hydrophobicity threshold for membrane integration Mol. Biol. Cell 21, 1662-1670
-
(2010)
Mol. Biol. Cell
, vol.21
, pp. 1662-1670
-
-
Junne, T.1
Kocik, L.2
Spiess, M.3
-
38
-
-
37249037182
-
Molecular code for transmembrane-helix recognition by the Sec61 translocon
-
Hessa, T., Meindl-Beinker, N. M., Bernsel, A., Kim, H., Sato, Y., Lerch-Bader, M., Nilsson, I., White, S. H., and von Heijne, G. (2007) Molecular code for transmembrane-helix recognition by the Sec61 translocon Nature 450, 1026-1030
-
(2007)
Nature
, vol.450
, pp. 1026-1030
-
-
Hessa, T.1
Meindl-Beinker, N.M.2
Bernsel, A.3
Kim, H.4
Sato, Y.5
Lerch-Bader, M.6
Nilsson, I.7
White, S.H.8
Von Heijne, G.9
-
39
-
-
67650869802
-
Insertion of short transmembrane helices by the Sec61 translocon
-
Jaud, S., Fernandez-Vidal, M., Nilsson, I., Meindl-Beinker, N. M., Hubner, N. C., Tobias, D. J., von Heijne, G., and White, S. H. (2009) Insertion of short transmembrane helices by the Sec61 translocon Proc. Natl. Acad. Sci. U.S.A. 106, 11588-11593
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 11588-11593
-
-
Jaud, S.1
Fernandez-Vidal, M.2
Nilsson, I.3
Meindl-Beinker, N.M.4
Hubner, N.C.5
Tobias, D.J.6
Von Heijne, G.7
White, S.H.8
-
40
-
-
80053632190
-
Lateral sorting in model membranes by cholesterol-mediated hydrophobic matching
-
Kaiser, H. J., Orlowski, A., Rog, T., Nyholm, T. K., Chai, W., Feizi, T., Lingwood, D., Vattulainen, I., and Simons, K. (2011) Lateral sorting in model membranes by cholesterol-mediated hydrophobic matching Proc. Natl. Acad. Sci. U.S.A. 108, 16628-16633
-
(2011)
Proc. Natl. Acad. Sci. U.S.A.
, vol.108
, pp. 16628-16633
-
-
Kaiser, H.J.1
Orlowski, A.2
Rog, T.3
Nyholm, T.K.4
Chai, W.5
Feizi, T.6
Lingwood, D.7
Vattulainen, I.8
Simons, K.9
-
41
-
-
0026909328
-
Mechanisms that determine the transmembrane disposition of proteins
-
High, S. and Dobberstein, B. (1992) Mechanisms that determine the transmembrane disposition of proteins Curr. Opin. Cell Biol. 4, 581-586
-
(1992)
Curr. Opin. Cell Biol.
, vol.4
, pp. 581-586
-
-
High, S.1
Dobberstein, B.2
|