Adenosine A1 receptors do not play a major role in the regulation of lipogenic gene expression in hepatocytes

European Journal of Pharmacology

Volumn 683, Issue 1-3, 2012, Pages 332-339

  Yang, Ming ^a   Chu, Ruth ^a   Chisholm, Jeffrey W ^a   Doege, Holger ^a   Belardinelli, Luiz ^a   Dhalla, Arvinder K ^a  

^a GILEAD SCIENCES   (United States)

Author keywords

Adenosine A1 receptor; Expression profiling; Hepatocytes; Lipogenesis; qPCR; Radioligand binding

Indexed keywords

2 [6 [(2 HYDROXYCYCLOPENTYL)AMINO]PURIN 9 YL] 5 [(2 FLUOROPHENYLTHIO)METHYL]OXOLANE 3,4 DIOL; 6 N CYCLOPENTYLADENOSINE; ADENOSINE A1 RECEPTOR; ADENOSINE A1 RECEPTOR AGONIST; CYCLIC AMP; FORSKOLIN; GS 9667; UNCLASSIFIED DRUG;

ADENOSINE A1 RECEPTOR GENE; ADULT; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING ASSAY; CELL STRAIN HEPG2; CONTROLLED STUDY; DRUG MECHANISM; DRUG RECEPTOR BINDING; FATTY ACID SYNTHASE GENE; FATTY ACID SYNTHESIS; FEMALE; GENE; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; LIGAND BINDING; LIVER CELL; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RAT; RECEPTOR DOWN REGULATION; RECEPTOR GENE; RECEPTOR UPREGULATION; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C GENE;

ADENOSINE A1 RECEPTOR AGONISTS; ANIMALS; CELL LINE; CELLS, CULTURED; CEREBRAL CORTEX; CRICETINAE; CRICETULUS; FATTY ACID SYNTHETASE COMPLEX; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HEPATOCYTES; HUMANS; LIPID METABOLISM; MALE; MICE; MIDDLE AGED; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, ADENOSINE A1; RECOMBINANT PROTEINS; RNA, MESSENGER; STEROL REGULATORY ELEMENT BINDING PROTEIN 1;

EID: 84860473083     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2012.03.012     Document Type: Article

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