Differential scanning fluorometry signatures as indicators of enzyme inhibitor mode of action: Case study of glutathione s-transferase

PLoS ONE

Volumn 7, Issue 4, 2012, Pages

  Lea, Wendy A ^a   Simeonov, Anton ^a  

^a NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME INHIBITOR; GLUTATHIONE; GLUTATHIONE CONJUGATE; GLUTATHIONE S TRANSFERASE INHIBITOR; GLUTATHIONE TRANSFERASE; UNCLASSIFIED DRUG; BIOMIMETIC MATERIAL; ISOENZYME;

ARTICLE; CONCENTRATION RESPONSE; DIFFERENTIAL SCANNING FLUOROMETRY; ENZYME DENATURATION; ENZYME INHIBITION; ENZYME SUBSTRATE; FLUOROMETRY; PROTEIN STABILITY; THERMODYNAMICS; ANIMAL; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; ENZYME STABILITY; ENZYMOLOGY; HUMAN; METHODOLOGY; PROTEIN DENATURATION; SCHISTOSOMA JAPONICUM; TEMPERATURE;

ANIMALS; BIOMIMETIC MATERIALS; ENZYME INHIBITORS; ENZYME STABILITY; FLUOROMETRY; GLUTATHIONE TRANSFERASE; HUMANS; ISOENZYMES; PROTEIN DENATURATION; SCHISTOSOMA JAPONICUM; TEMPERATURE;

EID: 84860472604     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0036219     Document Type: Article

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