Tramadol antinociception is potentiated by clonidine through α2-adrenergic and I2-imidazoline but not by endothelin ETA receptors in mice

European Journal of Pharmacology

Volumn 683, Issue 1-3, 2012, Pages 109-115

  Andurkar, Shridhar V ^a   Gendler, Liya ^b   Gulati, Anil ^a  

^a MIDWESTERN UNIVERSITY   (United States)

^b MIDWESTERN UNIVERSITY   (United States)

Author keywords

Adrenergic receptor; Antinociception; Clonidine; Endothelin receptor; Imidazoline receptor; Opioid receptor; Tramadol

Indexed keywords

5 DIMETHYLAMINO N (3,4 DIMETHYL 5 ISOXAZOLYL) 1 NAPHTHALENESULFONAMIDE; ALPHA ADRENERGIC RECEPTOR; CLONIDINE; CYCLO(DEXTRO TRYPTOPHYL DEXTRO ASPARTYLPROLYL DEXTRO VALYLLEUCYL); ENDOTHELIN A RECEPTOR; IDAZOXAN; IMIDAZOLINE I2 RECEPTOR; NALOXONE; TRAMADOL; YOHIMBINE;

ANIMAL EXPERIMENT; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG EFFECT; DRUG EFFICACY; DRUG POTENTIATION; HOT PLATE TEST; LATENT PERIOD; MALE; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; TAIL FLICK TEST;

ADRENERGIC ALPHA-2 RECEPTOR AGONISTS; ADRENERGIC ALPHA-2 RECEPTOR ANTAGONISTS; ANALGESICS; ANALGESICS, OPIOID; ANIMALS; CLONIDINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; IMIDAZOLINE RECEPTORS; MALE; MICE; MICE, INBRED STRAINS; NARCOTIC ANTAGONISTS; PAIN MEASUREMENT; RANDOM ALLOCATION; RECEPTOR, ENDOTHELIN A; RECEPTORS, ADRENERGIC, ALPHA-2; RECEPTORS, OPIOID, MU; TRAMADOL;

EID: 84860460801     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2012.03.016     Document Type: Article

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