A DNA vaccine expressing PB1 protein of influenza A virus protects mice against virus infection

Archives of Virology

Volumn 157, Issue 5, 2012, Pages 811-817

  Košík, Ivan ^a   Krejnusová, Ingrid ^a   Práznovská, Margaréta ^a   Poláková, Katarína ^b   Russ, Gustáv ^a  

^a INSTITUTE OF VIROLOGY   (Slovakia)

^b CANCER RESEARCH INSTITUTE   (Slovakia)

Author keywords

[No Author keywords available]

Indexed keywords

DNA VACCINE; INFLUENZA VACCINE; INFLUENZA VIRUS POLYMERASE BASIC PROTEIN 1; VIRUS ANTIBODY; VIRUS PROTEIN;

ANIMAL; ARTICLE; BAGG ALBINO MOUSE; CELL LINE; ENZYMOLOGY; FEMALE; GENETICS; HUMAN; IMMUNOLOGY; INFLUENZA; INFLUENZA VIRUS A; INFLUENZA VIRUS A H1N1; MALE; MOUSE; PHYSIOLOGY; VIROLOGY;

ANIMALS; ANTIBODIES, VIRAL; CELL LINE; FEMALE; HUMANS; INFLUENZA A VIRUS; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA VACCINES; INFLUENZA, HUMAN; MALE; MICE; MICE, INBRED BALB C; VACCINES, DNA; VIRAL PROTEINS;

INFLUENZA A VIRUS; INFLUENZAVIRUS A; MUS;

EID: 84860453014     PISSN: 03048608     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00705-012-1238-6     Document Type: Article

References (21)

1. Dormitzer PR, Galli G, Castellino F, Golding H, Khurana S, Del Giudice G, Rappuoli R (2011) Influenza vaccine immunology. Immunol Rev 239: 167-177. doi: 10. 1111/j. 1600-065X. 2010. 00974. x.
2. Moss RB (2009) Prospects for control of emerging infectious diseases with plasmid DNA vaccines. J Immune Based Ther Vaccines 7: 3. doi: 10. 1186/1476-8518-7-3.
3. Xu K, Ling ZY, Sun L, Xu Y, Bian C, He Y, Lu W, Chen Z, Sun B (2011) Broad humoral and cellular immunity elicited by a bivalent DNA vaccine encoding HA and NP genes from an H5N1 virus. Viral Immunol 24: 45-56. doi: 10. 1089/vim. 2010. 0056.
4. Košík I, Krejnusová I, Bystrická M, Poláková K, Russ G (2011) N-terminal region of the PB1-F2 protein is responsible for increased expression of influenza A viral protein PB1. Acta Virol 55: 45-53. doi: 10. 4149/av_2011_01_45.
5. Varecková E, Betáková T, Mucha V, Soláriková L, Kostolanský F, Waris M, Russ G (1995) Preparation of monoclonal antibodies for the diagnosis of influenza A infection using different immunization protocols. J Immunol Methods 180: 107-116. doi: 10. 1016/0022-1759(94)00307-I.
6. Birch-Machin I, Rowan A, Pick J, Mumford J, Binns M (1997) Expression of the nonstructural protein NS1 of equine influenza A virus: detection of anti-NS1 antibody in post infection equine sera. J Virol Methods 65: 255-263. doi: 10. 1016/S0166-0934(97)02189-7.
7. Tkácová M, Varecková E, Baker IC, Love JM, Ziegler T (1997) Evaluation of monoclonal antibodies for subtyping of currently circulating human type A influenza viruses. J Clin Microbiol 35: 1196-1198.
8. Ulmer A, Donnelly JB, Parker JJ, Rhodes SE, Felgner GH, Dwarki PL, Gromkowski VJ, Deck SH, DeWitt RR, Friedman CM, Hawe A, Leander LA, Martinez RK, Perry D, Shiver HC, Montgomery JW, Liu DL (1993) Heterologous protection against influenza by injection of DNA encoding a viral protein. Science 259: 1745-1749. doi: 10. 1126/science. 8456302.
9. Marjuki H, Alam MI, Ehrhardt C, Wagner R, Planz O, Klenk HD, Ludwig S, Pleschka S (2006) Membrane accumulation of influenza A virus hemagglutinin triggers nuclear export of the viral genome via protein kinase Calpha-mediated activation of ERK signaling. J Biol Chem 281: 16707-16715. doi: 10. 1074/jbc. M510233200.
10. Fodor E, Smith M (2004) The PA subunit is required for efficient nuclear accumulation of the PB1 subunit of the influenza A virus RNA polymerase complex. J Virol 78: 9144-9153. doi: 10. 1128/JVI. 78. 17. 9144-9153. 2004.
11. Chen W, Calvo PA, Malide D, Gibbs J, Schubert U, Bacik I, Basta S, O'Neill R, Schickli J, Palese P, Henklein P, Yewdell JW, Bennink JR (2001) A novel influenza A virus mitochondrial protein that induces cell death. Nat Med 7: 1306-1312. doi: 10. 1038/nm1201-1306.
12. Khurana S, Suguitan AL Jr, Rivera Y, Simmons CP, Lanzavecchia A, Sallusto F, Manischewitz J, King LR, Subbarao K, Golding H (2009) Antigenic fingerprinting of H5N1 avian influenza using convalescent sera and monoclonal antibodies reveals potential vaccine and diagnostic targets. PLoS Med 6e1000049. doi: 10. 1371/journal. pmed. 1000049.
13. Krejnusová I, Gocníková H, Bystrická M, Blaskovicová H, Poláková K, Yewdell J, Bennink J, Russ G (2009) Antibodies to PB1-F2 protein are induced in response to influenza A virus infection. Arch Virol 154: 1599-1604. doi: 10. 1007/s00705-009-0479-5.
14. Viallard JF, Pellegrin JL, Ranchin V, Schaeverbeke T, Dehais J, Longy-Boursier M, Ragnaud JM, Leng B, Moreau JF (1999) Th1 (IL-2, interferon-gamma (IFN-γ)) and Th2 (IL-10, IL-4) cytokine production by peripheral blood mononuclear cells (PBMC) from patients with systemic lupus erythematosus (SLE). Clin Exp Immunol 115: 189-195. doi: 10. 1046/j. 1365-2249. 1999. 00766. x.
15. Miyahara N, Swanson BJ, Takeda K, Taube C, Miyahara S, Kodama T, Dakhama A, Ott VL, Gelfand EW (2004) Effector CD8+ T cells mediate inflammation and airway hyper-responsiveness. Nat Med 10: 865-869. doi: 10. 1038/nm1081.
16. Gocník M, Fislová T, Mucha V, Sládková T, Russ G, Kostolansky F, Varecková E (2008) Antibodies induced by the HA2 glycopolypeptide of influenza virus haemagglutinin improve recovery from influenza A virus infection. J Gen Virol 89: 958-967. doi: 10. 1099/vir. 0. 83524-0.
17. Kodihalli S, Goto H, Kobasa DL, Krauss S, Kawaoka Y, Webster RG (1999) DNA vaccine encoding hemagglutinin provides protective immunity against H5N1 influenza virus infection in mice. J Virol 73: 2094-2098.
18. Zhang W, Li W, Li Y, Li H, Wang B, Wang F, Zhu Y, Jiang Z, Zhong L, Li M (2009) Immune effects against influenza A virus and a novel DNA vaccine with co-expression of haemagglutinin- and neuraminidase-encoding genes. J Med Microbiol 58: 845-854. doi: 10. 1099/jmm. 0. 006825-0.
19. Chen MW, Cheng TJ, Huang Y, Jan JT, Ma SH, Yu AL, Wong CH, Ho DD (2008) A consensus-hemagglutinin based DNA vaccine that protects mice against divergent H5N1 influenza viruses. Proc Natl Acad Sci USA 105: 13538-13543. doi: 10. 1073/pnas. 0806901105.
20. Wright PF, Neumann G, Kawaoka Y (2007) Orthomyxoviruses. In: Fields Virology, 5 edn, vol 2. Lippincott Williams and Wilkins, Philadelphia-Baltimore-New York-London-Buenos Aires-Hong Kong-Sydney-Tokyo, ISBN-13978-0-7817-6060-7.
21. Park KS, Seo YB, Lee JY, Im SJ, Seo SH, Song MS, Choi YK, Sung YC (2011) Complete protection against a H5N2 avian influenza virus by a DNA vaccine expressing a fusion protein of H1N1 HA and M2e. Vaccine 29: 5481-5487. doi: 10. 1016/j. vaccine. 2011. 05. 062.