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Volumn 3, Issue 5, 2012, Pages 584-591

A medicinal chemistry perspective on melting point: Matched molecular pair analysis of the effects of simple descriptors on the melting point of drug-like compounds

(9) Schultes, Sabine a De Graaf, Chris b Berger, Helmut a Mayer, Moriz a Steffen, Andreas a Haaksma, Eric E J a,b De Esch, Iwan J P b Leurs, Rob b Krämer, Oliver a

a BOEHRINGER INGELHEIM RCV GMBH AND CO KG (Austria)

b VU UNIVERSITY AMSTERDAM (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BROMINE; DRUG; HALOGEN; IODINE;

ANALYTIC METHOD; ARTICLE; CHEMISTRY; DRUG SOLUBILITY; HYDROGEN BOND; HYDROPHOBICITY; MATCHED MOLECULAR PAIR ANALYSIS; MEDICINAL CHEMISTRY; MELTING POINT; PRIORITY JOURNAL; PROCESS OPTIMIZATION; STRUCTURE ANALYSIS; TEMPERATURE MEASUREMENT;

EID: 84860433101 PISSN: 20402503 EISSN: 20402511 Source Type: Journal
DOI: 10.1039/c2md00313a Document Type: Article

Times cited : (24)

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