Mechanisms of intramolecular communication in a hyperthermophilic acylaminoacyl peptidase: A molecular dynamics investigation

PLoS ONE

Volumn 7, Issue 4, 2012, Pages

  Papaleo, Elena ^a,b   Renzetti, Giulia ^a   Tiberti, Matteo ^a  

^a UNIVERSITY OF MILANO BICOCCA   (Italy)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLAMINOACYL PEPTIDASE; ALANINE; ENZYME VARIANT; PEPTIDASE; PROLYL ENDOPEPTIDASE; UNCLASSIFIED DRUG; ACYLAMINOACYL-PEPTIDASE; ARCHAEAL PROTEIN; PEPTIDE HYDROLASE;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DELETION MUTANT; ENZYME ACTIVE SITE; ENZYME CONFORMATION; FUNCTIONAL PROTEOMICS; HYDROPHOBICITY; HYPERTHERMOPHILE; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULAR MODEL; PROCESS MODEL; PROTEIN DOMAIN; PROTEIN SECONDARY STRUCTURE; PROTEIN STABILITY; RESIDUE ANALYSIS; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; AMINO ACID SEQUENCE; BIOCATALYSIS; CHEMICAL PHENOMENA; CHEMISTRY; GENETICS; HEAT; MOLECULAR GENETICS; MUTATION; PROTEIN TERTIARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; ARCHAEAL PROTEINS; BIOCATALYSIS; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; HOT TEMPERATURE; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE DATA; MUTATION; PEPTIDE HYDROLASES; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY;

EID: 84860427628     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0035686     Document Type: Article

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