Comprehensive patterns in microRNA regulation of transcription factors during tumor metastasis

Journal of Cellular Biochemistry

Volumn 112, Issue 9, 2011, Pages 2210-2217

  Reshmi, G ^a   Sona, Charles ^a   Pillai, M Radhakrishna ^a  

^a RAJIV GANDHI CENTRE FOR BIOTECHNOLOGY   (India)

Author keywords

Feed back loop; Feed forward loop; Metastasis; Micrornas; Transcription factor

Indexed keywords

ALPHA TROPOMYOSIN; BASIC LEUCINE ZIPPER TRANSCRIPTION FACTOR; BIOLOGICAL FACTOR; CCAAT ENHANCER BINDING PROTEIN; FATTY ACID BINDING PROTEIN; MICRORNA; MYC PROTEIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; RAS PROTEIN; STAT PROTEIN; STAT3 PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR FOSL2; TRANSCRIPTION FACTOR HOXA5; TRANSCRIPTION FACTOR HOXD10; TRANSCRIPTION FACTOR RUNX1; UNCLASSIFIED DRUG; UVOMORULIN;

ACUTE MYELOBLASTIC LEUKEMIA; ANGIOGENESIS; ARTICLE; AUTOREGULATION; BREAST CANCER; CANCER INVASION; CANCER RELAPSE; CELL PROLIFERATION; CELL SURVIVAL; CELL TRANSFORMATION; DOWN REGULATION; EPITHELIAL MESENCHYMAL TRANSITION; FEEDBACK FORWARD LOOP; FEEDBACK SYSTEM; HUMAN; LYMPH NODE METASTASIS; METASTASIS; PANCREAS CANCER; POSITIVE AUTOREGULATION; PRIORITY JOURNAL; TRANSCRIPTION REGULATION; TUMOR VOLUME;

CELL MOVEMENT; FEEDBACK, PHYSIOLOGICAL; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE REGULATORY NETWORKS; HUMANS; MICRORNAS; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; NEOVASCULARIZATION, PATHOLOGIC; TRANSCRIPTION FACTORS;

EID: 84860422750     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.23148     Document Type: Article

References (49)

1. Alon U,. 2007. Network motifs: Theory and experimental approaches. Nat Rev Genet 8: 450-461. (Pubitemid 46789247)
2. Bartel DP,. 2004. MicroRNAs: Genomics, biogenesis, mechanism, and function. Cell 116: 281-297.
3. Batada NN, Hurst LD, Tyers M,. 2006. Evolutionary and physiological importance of hub proteins. PLoS Comput Biol 2: e88.
4. Bommer GT, Gerin I, Feng Y, Kaczorowski AJ, Kuick R, Love RE, Zhai Y, Giordano TJ, Qin ZS, Moore BB,. 2007. p53-mediated activation of miRNA34 candidate tumor-suppressor genes. Curr Biol 17: 1298-1307. (Pubitemid 47176893)
5. Boominathan L,. 2009. p63, p73, & p53 are negative regulators of epithelial to mesenchymal transition (EMT), invasion & metastasis. Nature Proceedings DOI: 10.1038/npre. 4109.1
6. Boyd D, Simon C, Nemechek AJ, Boyd D, O'Malley BW Jr, Goepfert H, Flaitz CM, Hicks MJ,. 1998. An orthotopic floor-of-mouth cancer model allows quantification of tumor invasion. Laryngoscope 108: 1686-1691.
7. Boyer LA, Lee TI, Cole MF, Johnstone SE, Levine SS, Zucker JP, Guenther MG, Kumar RM, Murray HL, Jenner RG, Gifford DK, Melton DA, Jaenisch R, Young RA,. 2005. Core transcriptional regulatory circuitry in human embryonic stem cells. Cell 122 (6): 947-956. (Pubitemid 41345211)
8. Bracken CP, Gregory PA, Kolesnikoff N, Bert AG, Wang J, Shannon MF, Goodall GJ,. 2008. A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition. Cancer Res 68: 7846-7854.
9. Brosh R, Shalgi R, Liran A, Landan G, Korotayev K, Nguyen GH, Enerly E, Johnsen H, Buganim Y, Solomon H, Goldstein I, Madar S, Goldfinger N, Børresen-Dale A-L, Ginsberg D, Harris CC, Pilpel Y, Oren M, Rotter V,. 2008. p53-repressed miRNAs are involved with E2F in a feed forward loop promoting proliferation. Mol Syst Biol 4: 229.
10. Chambers AF, Groom AC, MacDonald IC,. 2002. Dissemination and growth of cancer cells in metastatic sites. Nat Rev Cancer 2: 563-572. (Pubitemid 37328923)
11. Cohen EE, Zhu H, Lingen MW, Martin LE, Kuo WL, Choi EA, Kocherginsky M, Parker JS, Chung CH, Rosner MR,. 2009. A feed-forward loop involving protein kinase Calpha and microRNAs regulates tumor cell cycle. Cancer Res 69: 65-74.
12. Deplancke B, Vermeirssen V, Arda HE, Martinez NJ, Walhout AJM,. 2004. Gateway-compatible yeast one hybrid screens. Genome Res 14: 2093-2101. (Pubitemid 39440191)
13. Dews M, Homayouni A, Yu D, Murphy D, Sevignani C, Wentzel E, Furth EE, Lee WM, Enders GH, Mendell JT,. 2006. Augmentation of tumor angiogenesis by a Myc-activated microRNA cluster. Nat Genet 38: 1060-1065. (Pubitemid 44325933)
14. Farh KK, Kai-How Farh Kyle, Grimson A, Jan C, Lewis BP, Johnston WK, Lim LP, Burge C, Bartel DP,. 2005. The widespread impact of mammalian microRNAs on mRNA repression and evolution. Science 310: 1817-1821. (Pubitemid 41814382)
15. Fasanaro P, D'Alessandra Y, Di Stefano V, Melchionna R, Romani S, Pompilio G, Capogrossi MC, Martelli F,. 2008. MicroRNA-210 modulates endothelial cell response to hypoxia and inhibits the receptor tyrosine kinase ligand Ephrin-A3. J Biol Chem 283: 15878-15883.
16. Fazi F, Racanicchi S, Zardo G, Starnes LM, Mancini M, Travaglini L, Diverio D, Ammatuna E, Cimino G, Lo-Coco F, Grignani F, Nervi C,. 2007. Epigenetic silencing of the myelopoiesis regulator microRNA-223 by the AML1/ETO oncoprotein. Cancer Cell 12: 457-466. (Pubitemid 350046404)
17. Feng R, Chen X, Yu Y, Su L, Yu B, Li JQ, Sengupta S,. 2008. MicroRNA 29c is down-regulated in nasopharyngeal carcinomas, up-regulating mRNAs encoding extracellular matrix proteins. Proc Natl Acad Sci USA 105: 5874-5878. (Pubitemid 351758465)
18. Harbison CT, Gordon DB, Lee TI, Rinaldi NJ, Macisaac KD, Danford TW, Hannett NM, Tagne J-B, Reynolds DB, Yoo J, Jennings EG, Zeitlinger J, Pokholok DK, Kellis M, Rolfe PA, Takusagawa KT, Lander ES, Gifford DK, Fraenkel E, Young1 RA,. 2004. Transcriptional regulatory code of a eukaryotic genome. Nature 431: 99-104. (Pubitemid 39215116)
19. Hobert O,. 2008. MicroRNAs gene regulation by transcription factors and miRNAs. Science 319: 1785.
20. Hua Z, Lv Q, Ye W, Wong CK, Cai G, Gu D, Ji Y, Zhao C, Wang J, Yang BB, et al. 2006. MiRNA-directed regulation of VEGF and other angiogenic factors under hypoxia. PLoS ONE 1: e116.
21. Hunter KW, Crawford NP, Alsarraj J,. 2008. Mechanisms of metastasis. Breast Cancer Res 10 (Suppl 1): S2.
22. Johnston RJ, Chang S, Etchberger JF, Ortiz CO, Hobert O,. 2005. MicroRNAs acting in a double-negative feedback loop to control a neuronal cell fate decision. Proc Natl Acad Sci 102: 12449-12454. (Pubitemid 41266379)
23. Kim J, Inoue K, Ishii J, Vanti WB, Voronov SV, Murchison E, Hannon G, Abeliovich A,. 2007. A MicroRNA feedback circuit in midbrain dopamine neurons. Science 317: 1220-1224.
24. Koshiol J,. 2010. Strengths and limitations of laboratory procedures for MicroRNA detection. Cancer Epidemiol. Biomarkers Prev 19: 907-911.
25. leSage C, Nagel, R, Egan, DA, Schrier M, Mesman E, Mangiola A, Anile C, Maira G, Mercatelli N, Ciafre SA, Farace MG, Agami R,. 2007. Regulation of the p27(Kip1) tumor suppressor by miR-221 and miR-222 promotes cancer cell proliferation. Embo J 26: 3699-3708. (Pubitemid 47236875)
26. Leber MF, Efferth T,. 2009. Molecular principles of cancer invasion and metastasis. Int J Oncol 34: 881-895.
27. Ma L, Teruya-Feldstein J, Weinberg RA,. 2007. Tumour invasion and metastasis initiated by microRNA-10b in breast cancer. Nature 449: 682-688. (Pubitemid 47552092)
28. Mangan S, Zaslaver A, Alon U,. 2003. The coherent feedforward loop serves as a sign sensitive delay element in transcription networks. J Mol Biol 334: 197-204. (Pubitemid 37361089)
29. Milo R, Shen-Orr SS, Itzkovitz S, Kashtan n, Chklovskii D, Alon U,. 2002. Network motifs: Simple building blocks of complex networks. Science 298 (5594): 824-827. (Pubitemid 35231534)
30. Qihong H, Gumireddy K, Schrier M, le Sage C, Nagel R, Nair S, Egan DA, Li A, Huang G, Klein-Szanto AJ, Gimotty PA, Katsaros D, Coukos G, Zhang L, Puré E, Agami R,. 2008. The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis. Nat Cell Biol 10: 2202-2210.
31. Sandmann T, Jensen LJ, Jakobsen JS, Karzynski MM, Eichenlaub MP, Bork P, Furlong EEM,. 2006. A temporal map of transcription factor activity: Mef2 directly regulates target genes at all stages of muscle development. Dev Cell 10: 797-807. (Pubitemid 43779116)
32. Schulte JH, Horn S, Otto T, Samans B, Heukamp LC, Eilers UC,. 2008. MYCN regulates oncogenic MicroRNAs in neuroblastoma. Int J Cancer 122: 699-704. (Pubitemid 350308967)
33. Self Fish JE, Santoro MM, Morton SU, Yu S, Yeh RF, Wythe JD, Ivey KN, Bruneau BG, Stainier DY, Srivastava D,. 2008. miR-126 regulates angiogenic signaling and vascular integrity. Dev Cell 15: 272-284.
34. Shalgi R, Lieber D, Oren M,., Pilpel Y, 2007. Global and local architecture of the mammalian microRNA-transcription factor regulatory network. PLoS Comput Biol 3: e131.
35. Shen-Orr SS, Milo R, Mangan S, Alon U,. 2002. Network motifs in the transcriptional regulation network of Escherichia coli. Nat Genet 31: 64-68.
36. Sood P, Krek A, Zavolan M, Macino G, Rajewsky N,. 2006. Cell-type-specific signatures of microRNAs on target mRNA expression. Proc Natl Acad Sci USA 103: 2746-2751.
37. Stark A, Brennecke J, Bushati N, Russell RB, Cohen SM,. 2005. Animal MicroRNAs confer robustness to gene expression and have a significant impact on 3'UTR evolution. Cell 123: 1133-1146. (Pubitemid 41785426)
38. Sylvestre Y, De Guire V, Querido E, Mukhopadhyay UK, Bourdeau V, Major F, Ferbeyre G, Chartrand P,. 2007. An E2F/miR-20a autoregulatory feedback loop. J Biol Chem 282: 2135-2143. (Pubitemid 47076740)
39. Tavazoie SF, Alarcón C, Oskarsson T, Padua D, Wang Q, Bos PD, Gerald WL, Massagué J,. 2008. Endogenous human microRNAs that suppress breast cancer metastasis. Nature 451: 147-152.
40. Tsang J, Zhu J, van Oudenaarden A,. 2007. MicroRNA-mediated feedback and feedforward loops are recurrent network motifs in mammals. Mol Cell 26: 753-767. (Pubitemid 46856248)
41. Vandewalle C, Van Roy F, Berxa G,. 2009. The role of the ZEB family of transcription factors in development and disease. Cell Mol Life Sci 66: 773-787.
42. Varghese J, Cohen SM,. 2007. microRNA miR-14 acts to modulate a positive autoregulatory loop controlling steroid hormone signaling in Drosophila. Genes Dev 21: 2277-2282. (Pubitemid 47443333)
43. Vermeirssen V, Barrasa MI, Hidalgo C, Babon JAB, Sequerra R, Doucette-Stam L, Barabasi AL, Walhout AJM,. 2007. Transcription factor modularity in a gene-centered C. elegans core neuronal protein-DNA interaction network. Genome Res 17: 1061-1071. (Pubitemid 47026353)
44. Wang E, Purisima E,. 2005. Network motifs are enriched with transcription factors whose transcripts have short half-lives. Trends Genet 21: 492-495. (Pubitemid 41132582)
45. Wang XH, Qian RZ, Zhang W, Chen SF, Jin HM, Hu RM,. 2009. MicroRNA-320 expression in myocardial microvascular endothelial cell and its relationship with insulin-like growth factor-1 in type 2 diabetic rats. Clin Exp Pharmacol Physio 36: 181-188.
46. Woods K, Thomson JM, Hammond SM,. 2007. Direct regulation of an oncogenic micro-RNA cluster by E2F transcription factors. J Biol Chem 282: 2130-2134. (Pubitemid 47076737)
47. Yeger-Lotem E, Sattath S, Kashtan N, Itzkovitz S,. 2004. Network motifs in integrated cellular networks of transcription-regulation and protein-protein interactions. Proc Natl Acad Sci USA 101: 5934-5939. (Pubitemid 38520506)
48. Yun Chen, Gorski DH,. 2008. Regulation of angiogenesis through a microRNA (miR-130a) that down-regulates antiangiogenic homeobox genes GAX and HOXA5. Blood 111: 1217-1226. (Pubitemid 351213403)
49. Zhu S, Si ML, Wu H, Mo YY,. 2007. MicroRNA-21 targets the tumor suppressor gene tropomyosin1 (TPM1). J Biol Chem 282 (19): 14328-14336. (Pubitemid 47100416)