-
1
-
-
70349773104
-
Healing and hurting: Molecular mechanisms, functions, and pathologies of cellular senescence
-
Adams PD. (2009). Healing and hurting: molecular mechanisms, functions, and pathologies of cellular senescence. Mol Cell 36: 2-14.
-
(2009)
Mol Cell
, vol.36
, pp. 2-14
-
-
Adams, P.D.1
-
2
-
-
3042761646
-
BubR1 insufficiency causes early onset of aging-associated phenotypes and infertility in mice
-
DOI 10.1038/ng1382
-
Baker DJ, Jeganathan KB, Cameron JD, Thompson M, Juneja S, Kopecka A et al. (2004). BubR1 insufficiency causes early onset of aging-associated phenotypes and infertility in mice. Nat Genet 36: 744-749. (Pubitemid 38886637)
-
(2004)
Nature Genetics
, vol.36
, Issue.7
, pp. 744-749
-
-
Baker, D.J.1
Jeganathan, K.B.2
Cameron, J.D.3
Thompson, M.4
Juneja, S.5
Kopecka, A.6
Kumar, R.7
Jenkins, R.B.8
De Groen, P.C.9
Roche, P.10
Van Deursen, J.M.11
-
3
-
-
36749080303
-
E2F-associated chromatin modifiers and cell cycle control
-
DOI 10.1016/j.ceb.2007.10.003, PII S0955067407001408, Cell Differentiation / Cell Division, Growth and Death
-
Blais A, Dynlacht BD. (2007). E2F-associated chromatin modifiers and cell cycle control. Curr Opin Cell Biol 19: 658-662. (Pubitemid 350216425)
-
(2007)
Current Opinion in Cell Biology
, vol.19
, Issue.6
, pp. 658-662
-
-
Blais, A.1
Dynlacht, B.D.2
-
4
-
-
0033800987
-
Loss of p19(ARF) eliminates the requirement for the pRB-binding motif in simian virus 40 large T antigen-mediated transformation
-
Chao HH, Buchmann AM, DeCaprio JA. (2000). Loss of p19(ARF) eliminates the requirement for the pRB-binding motif in simian virus 40 large T antigen-mediated transformation. Mol Cell Biol 20: 7624-7633.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 7624-7633
-
-
Chao, H.H.1
Buchmann, A.M.2
DeCaprio, J.A.3
-
5
-
-
23744443826
-
Aneuploidy: A matter of bad connections
-
DOI 10.1016/j.tcb.2005.06.008, PII S0962892405001601
-
Cimini D, Degrassi F. (2005). Aneuploidy: a matter of bad connections. Trends Cell Biol 15: 442-451. (Pubitemid 41125776)
-
(2005)
Trends in Cell Biology
, vol.15
, Issue.8
, pp. 442-451
-
-
Cimini, D.1
Degrassi, F.2
-
6
-
-
10744222730
-
Simian virus 40 large T antigen targets the spindle assembly checkpoint protein Bub1
-
DOI 10.1073/pnas.0308006100
-
Cotsiki M, Lock RL, Cheng Y, Williams GL, Zhao J, Perera D et al. (2004). Simian virus 40 large T antigen targets the spindle assembly checkpoint protein Bub1. Proc Natl Acad Sci USA 101: 947-952. (Pubitemid 38160564)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.4
, pp. 947-952
-
-
Cotsiki, M.1
Lock, R.L.2
Cheng, Y.3
Williams, G.L.4
Zhao, J.5
Perera, D.6
Freire, R.7
Entwistle, A.8
Golemis, E.A.9
Roberts, T.M.10
Jat, P.S.11
Gjoerup, O.V.12
-
7
-
-
0029047362
-
A biomarker that identifies senescent human cells in culture and in aging skin in vivo
-
Dimri GP, Lee X, Basile G, Acosta M, Scott G, Roskelley C et al. (1995). A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc Natl Acad Sci USA 92: 9363-9367.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 9363-9367
-
-
Dimri, G.P.1
Lee, X.2
Basile, G.3
Acosta, M.4
Scott, G.5
Roskelley, C.6
-
8
-
-
10044293367
-
Inhibition of oncogenic transformation by mammalian Lin-9, a pRB-associated protein
-
DOI 10.1038/sj.emboj.7600470
-
Gagrica S, Hauser S, Kolfschoten I, Osterloh L, Agami R, Gaubatz S. (2004). Inhibition of oncogenic transformation by mammalian Lin-9, a pRB-associated protein. EMBO J 23: 4627-4638. (Pubitemid 39657862)
-
(2004)
EMBO Journal
, vol.23
, Issue.23
, pp. 4627-4638
-
-
Gagrica, S.1
Hauser, S.2
Kolfschoten, I.3
Osterloh, L.4
Agami, R.5
Gaubatz, S.6
-
9
-
-
0033634869
-
E2F4 and E2F5 play an essential role in pocket protein-mediated G1 control
-
Gaubatz S, Lindeman GJ, Ishida S, Jakoi L, Nevins JR, Livingston DM et al. (2000). E2F4 and E2F5 play an essential role in pocket protein-mediated G1 control. Mol Cell 6: 729-735.
-
(2000)
Mol Cell
, vol.6
, pp. 729-735
-
-
Gaubatz, S.1
Lindeman, G.J.2
Ishida, S.3
Jakoi, L.4
Nevins, J.R.5
Livingston, D.M.6
-
10
-
-
67649522162
-
Boveri revisited: Chromosomal instability, aneuploidy and tumorigenesis
-
Holland AJ, Cleveland DW. (2009). Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis. Nat Rev Mol Cell Biol 10: 478-487.
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, pp. 478-487
-
-
Holland, A.J.1
Cleveland, D.W.2
-
11
-
-
0027535098
-
Association of p53 binding and immortalization of primary C57BL/6 mouse embryo fibroblasts by using simian virus 40 T-antigen mutants bearing internal overlapping deletion mutations
-
Kierstead TD, Tevethia MJ. (1993). Association of p53 binding and immortalization of primary C57BL/6 mouse embryo fibroblasts by using simian virus 40 T-antigen mutants bearing internal overlapping deletion mutations. J Virol 67: 1817-1829. (Pubitemid 23088353)
-
(1993)
Journal of Virology
, vol.67
, Issue.4
, pp. 1817-1829
-
-
Kierstead, T.D.1
Tevethia, M.J.2
-
12
-
-
65049089886
-
A Lin-9 complex is recruited by B-Myb to activate transcription of G(2)/M genes in undifferentiated embryonal carcinoma cells
-
Knight AS, Notaridou M, Watson RJ. (2009). A Lin-9 complex is recruited by B-Myb to activate transcription of G(2)/M genes in undifferentiated embryonal carcinoma cells. Oncogene 28: 1737-1747.
-
(2009)
Oncogene
, vol.28
, pp. 1737-1747
-
-
Knight, A.S.1
Notaridou, M.2
Watson, R.J.3
-
13
-
-
13944274222
-
FoxM1 is required for execution of the mitotic programme and chromosome stability
-
DOI 10.1038/ncb1217
-
Laoukili J, Kooistra MR, Bras A, Kauw J, Kerkhoven RM, Morrison A et al. (2005). FoxM1 is required for execution of the mitotic programme and chromosome stability. Nat Cell Biol 7: 126-136. (Pubitemid 40268127)
-
(2005)
Nature Cell Biology
, vol.7
, Issue.2
, pp. 126-136
-
-
Laoukili, J.1
Kooistra, M.R.H.2
Bras, A.3
Kauw, J.4
Kerkhoven, R.M.5
Morrison, A.6
Clevers, H.7
Medema, R.H.8
-
14
-
-
34249109173
-
Evolutionarily Conserved Multisubunit RBL2/p130 and E2F4 Protein Complex Represses Human Cell Cycle-Dependent Genes in Quiescence
-
DOI 10.1016/j.molcel.2007.04.015, PII S1097276507002511
-
Litovchick L, Sadasivam S, Florens L, Zhu X, Swanson SK, Velmurugan S et al. (2007). Evolutionarily conserved multisubunit RBL2/p130 and E2F4 protein complex represses human cell cycle-dependent genes in quiescence. Mol Cell 26: 539-551. (Pubitemid 46779093)
-
(2007)
Molecular Cell
, vol.26
, Issue.4
, pp. 539-551
-
-
Litovchick, L.1
Sadasivam, S.2
Florens, L.3
Zhu, X.4
Swanson, S.K.5
Velmurugan, S.6
Chen, R.7
Washburn, M.P.8
Liu, X.S.9
DeCaprio, J.A.10
-
15
-
-
77950650906
-
CENP-A reduction induces a p53-dependent cellular senescence response to protect cells from executing defective mitoses
-
Maehara K, Takahashi K, Saitoh S. (2010). CENP-A reduction induces a p53-dependent cellular senescence response to protect cells from executing defective mitoses. Mol Cell Biol 30: 2090-2104.
-
(2010)
Mol Cell Biol
, vol.30
, pp. 2090-2104
-
-
Maehara, K.1
Takahashi, K.2
Saitoh, S.3
-
16
-
-
34247333444
-
The spindle-assembly checkpoint in space and time
-
DOI 10.1038/nrm2163, PII NRM2163
-
Musacchio A, Salmon ED. (2007). The spindle-assembly checkpoint in space and time. Nat Rev Mol Cell Biol 8: 379-393. (Pubitemid 46643240)
-
(2007)
Nature Reviews Molecular Cell Biology
, vol.8
, Issue.5
, pp. 379-393
-
-
Musacchio, A.1
Salmon, E.D.2
-
17
-
-
33846231036
-
The human synMuv-like protein LIN-9 is required for transcription of G2/M genes and for entry into mitosis
-
DOI 10.1038/sj.emboj.7601478, PII 7601478
-
Osterloh L, von Eyss B, Schmit F, Rein L, Hubner D, Samans B et al. (2007). The human synMuv-like protein LIN-9 is required for transcription of G2/M genes and for entry into mitosis. EMBO J 26: 144-157. (Pubitemid 46094707)
-
(2007)
EMBO Journal
, vol.26
, Issue.1
, pp. 144-157
-
-
Osterloh, L.1
Von Eyss, B.2
Schmit, F.3
Rein, L.4
Hubner, D.5
Samans, B.6
Hauser, S.7
Gaubatz, S.8
-
18
-
-
36749079269
-
Mammalian Mip/LIN-9 interacts with either the p107, p130/E2F4 repressor complex or B-Myb in a cell cycle-phase-dependent context distinct from the Drosophila dREAM complex
-
DOI 10.1038/sj.onc.1210562, PII 1210562
-
Pilkinton M, Sandoval R, Colamonici OR. (2007a). Mammalian Mip/LIN-9 interacts with either the p107, p130/E2F4 repressor complex or B-Myb in a cell cycle-phase-dependent context distinct from the Drosophila dREAM complex. Oncogene 26: 7535-7543. (Pubitemid 350207709)
-
(2007)
Oncogene
, vol.26
, Issue.54
, pp. 7535-7543
-
-
Pilkinton, M.1
Sandoval, R.2
Colamonici, O.R.3
-
19
-
-
33847004744
-
Mip/LIN-9 regulates the expression of B-Myb and the induction of cyclin A, cyclin B, and CDK1
-
DOI 10.1074/jbc.M609924200
-
Pilkinton M, Sandoval R, Song J, Ness SA, Colamonici OR. (2007b). Mip/LIN-9 regulates the expression of B-Myb and the induction of cyclin A, cyclin B, and CDK1. J Biol Chem 282: 168-175. (Pubitemid 47076644)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.1
, pp. 168-175
-
-
Pilkinton, M.1
Sandova, R.2
Song, J.3
Ness, S.A.4
Colamonici, O.R.5
-
20
-
-
77953414532
-
Lin9, a subunit of the mammalian DREAM complex, is essential for embryonic development, for survival of adult mice, and for tumor suppression
-
Reichert N, Wurster S, Ulrich T, Schmitt K, Hauser S, Probst L et al. (2010). Lin9, a subunit of the mammalian DREAM complex, is essential for embryonic development, for survival of adult mice, and for tumor suppression. Mol Cell Biol 30: 2896-2908.
-
(2010)
Mol Cell Biol
, vol.30
, pp. 2896-2908
-
-
Reichert, N.1
Wurster, S.2
Ulrich, T.3
Schmitt, K.4
Hauser, S.5
Probst, L.6
-
21
-
-
58249094849
-
Impaired Bub1 function in vivo compromises tension-dependent checkpoint function leading to aneuploidy and tumorigenesis
-
Schliekelman M, Cowley DO, O'Quinn R, Oliver TG, Lu L, Salmon ED et al. (2009). Impaired Bub1 function in vivo compromises tension-dependent checkpoint function leading to aneuploidy and tumorigenesis. Cancer Res 69: 45-54.
-
(2009)
Cancer Res
, vol.69
, pp. 45-54
-
-
Schliekelman, M.1
Cowley, D.O.2
O'Quinn, R.3
Oliver, T.G.4
Lu, L.5
Salmon, E.D.6
-
22
-
-
34548203947
-
2/M genes
-
Schmit F, Korenjak M, Mannefeld M, Schmitt K, Franke C, Eyss BV et al. (2007). LINC, a human complex that is related to pRB-containing complexes in invertebrates regulates the expression of G2/M genes. Cell Cycle 6: 1903-1913. (Pubitemid 47327909)
-
(2007)
Cell Cycle
, vol.6
, Issue.15
, pp. 1903-1913
-
-
Schmit, F.1
Korenjak, M.2
Mannefeld, M.3
Schmitt, K.4
Franke, C.5
Von Eyss, B.6
Gagrica, S.7
Hanel, F.8
Brehm, A.9
Gaubatz, S.10
-
23
-
-
0031586589
-
The tumor suppressor protein p16INK4a
-
Serrano M. (1997). The tumor suppressor protein p16INK4a. Exp Cell Res 237: 7-13.
-
(1997)
Exp Cell Res
, vol.237
, pp. 7-13
-
-
Serrano, M.1
-
24
-
-
77950520862
-
ARF-induced downregulation of Mip130/LIN-9 protein levels mediates a positive feedback that leads to increased expression of p16Ink4a and p19Arf
-
Song J, Sandoval R, Pilkinton MA, Tian X, Raychaudhuri P, Colamonici OR. (2010). ARF-induced downregulation of Mip130/LIN-9 protein levels mediates a positive feedback that leads to increased expression of p16Ink4a and p19Arf. Oncogene 29: 1976-1986.
-
(2010)
Oncogene
, vol.29
, pp. 1976-1986
-
-
Song, J.1
Sandoval, R.2
Pilkinton, M.A.3
Tian, X.4
Raychaudhuri, P.5
Colamonici, O.R.6
-
25
-
-
0030794278
-
Inactivation of pRB-related proteins p130 and p107 mediated by the J domain of simian virus 40 large T antigen
-
Stubdal H, Zalvide J, Campbell KS, Schweitzer C, Roberts TM, DeCaprio JA. (1997). Inactivation of pRB-related proteins p130 and p107 mediated by the J domain of simian virus 40 large T antigen. Mol Cell Biol 17: 4979-4990. (Pubitemid 27357597)
-
(1997)
Molecular and Cellular Biology
, vol.17
, Issue.9
, pp. 4979-4990
-
-
Stubdal, H.1
Zalvide, J.2
Campbell, K.S.3
Schweitzer, C.4
Roberts, T.M.5
Decaprio, J.A.6
-
26
-
-
0029989279
-
Simian virus 40 large T antigen alters the phosphorylation state of the RB-related proteins p130 and p107
-
Stubdal H, Zalvide J, DeCaprio JA. (1996). Simian virus 40 large T antigen alters the phosphorylation state of the RB-related proteins p130 and p107. J Virol 70: 2781-2788. (Pubitemid 26124275)
-
(1996)
Journal of Virology
, vol.70
, Issue.5
, pp. 2781-2788
-
-
Stubdal, H.1
Zalvide, J.2
DeCaprio, J.A.3
-
27
-
-
34147143631
-
Definition of pRB- and p53-dependent and -independent steps in HIRA/ASF1a-mediated formation of senescence-associated heterochromatin foci
-
DOI 10.1128/MCB.01592-06
-
Ye X, Zerlanko B, Zhang R, Somaiah N, Lipinski M, Salomoni P et al. (2007). Definition of pRB- and p53-dependent and -independent steps in HIRA/ASF1a-mediated formation of senescence-associated heterochromatin foci. Mol Cell Biol 27: 2452-2465. (Pubitemid 46581338)
-
(2007)
Molecular and Cellular Biology
, vol.27
, Issue.7
, pp. 2452-2465
-
-
Ye, X.1
Zerlanko, B.2
Zhang, R.3
Somaiah, N.4
Lipinski, M.5
Salomoni, P.6
Adams, P.D.7
-
28
-
-
0029091312
-
Role of pRb-related proteins in simian virus 40 large-T-antigen-mediated transformation
-
Zalvide J, DeCaprio JA. (1995). Role of pRb-related proteins in simian virus 40 large-T-antigen-mediated transformation. Mol Cell Biol 15: 5800-5810.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 5800-5810
-
-
Zalvide, J.1
DeCaprio, J.A.2
|