-
1
-
-
47249124078
-
Human regulatory T cells: Role in autoimmune disease and therapeutic opportunities
-
DOI 10.1111/j.1600-065X.2008.00637.x
-
Brusko TM, Putnam AL, Bluestone JA. Humanregulatory T cells: role in autoimmune disease and therapeutic opportunities. Immunol Rev Jun 2008;223:371-90. (Pubitemid 351986182)
-
(2008)
Immunological Reviews
, vol.223
, Issue.1
, pp. 371-390
-
-
Brusko, T.M.1
Putnam, A.L.2
Bluestone, J.A.3
-
2
-
-
47249102067
-
+ T-regulatory cells: Toward therapy for human diseases
-
DOI 10.1111/j.1600-065X.2008.00634.x
-
Allan SE, Broady R, Gregori S, Himmel ME, Locke N, Roncarolo MG, et al. CD4+ Tregulatory cells: toward therapy for human diseases. Immunol Rev Jun 2008;223: 391-421. (Pubitemid 351986179)
-
(2008)
Immunological Reviews
, vol.223
, Issue.1
, pp. 391-421
-
-
Allan, S.E.1
Broady, R.2
Gregori, S.3
Himmel, M.E.4
Locke, N.5
Roncarolo, M.G.6
Bacchetta, R.7
Levings, M.K.8
-
3
-
-
0030704726
-
+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
-
DOI 10.1038/39614
-
Groux H, O'Garra A, Bigler M, Rouleau M, Antonenko S, de Vries JE, et al. A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis. Nature Oct 16 1997;389:737-42. (Pubitemid 27458961)
-
(1997)
Nature
, vol.389
, Issue.6652
, pp. 737-742
-
-
Groux, H.1
O'Garra, A.2
Bigler, M.3
Rouleau, M.4
Antonenko, S.5
De Vries, J.E.6
Roncarolo, M.G.7
-
4
-
-
0242412365
-
+ T Cells in the Control of Inflammation
-
Foussat A, Cottrez F, Brun V, Fournier N, Breittmayer JP, Groux H. A comparative study between T regulatory type 1 and CD4+CD25+ T cells in the control of inflammation. J Immunol Nov 15 2003;171(10):5018-26. (Pubitemid 37432782)
-
(2003)
Journal of Immunology
, vol.171
, Issue.10
, pp. 5018-5026
-
-
Foussat, A.1
Cottrez, F.2
Brun, V.3
Fournier, N.4
Breittmayer, J.-P.5
Groux, H.6
-
5
-
-
0037018104
-
+ T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines
-
DOI 10.1084/jem.20011629
-
Barrat FJ, Cua DJ, Boonstra A, Richards DF, Crain C, Savelkoul HF, et al. In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2- inducing cytokines. J Exp Med Mar 4 2002;195:603-16. (Pubitemid 34461505)
-
(2002)
Journal of Experimental Medicine
, vol.195
, Issue.5
, pp. 603-616
-
-
Barrat, F.J.1
Cua, D.J.2
Boonstra, A.3
Richards, D.F.4
Crain, C.5
Savelkoul, H.F.6
De Waal-Malefyt, R.7
Coffman, R.L.8
Hawrylowicz, C.M.9
O'Garra, A.10
-
6
-
-
0034327264
-
T regulatory cells 1 inhibit a Th2-specific response in vivo
-
Cottrez F, Hurst SD, Coffman RL, Groux H. T regulatory cells 1 inhibit a Th2-specific response in vivo. J Immunol 2000;165:4848-53.
-
(2000)
J Immunol
, vol.165
, pp. 4848-4853
-
-
Cottrez, F.1
Hurst, S.D.2
Coffman, R.L.3
Groux, H.4
-
7
-
-
61749100051
-
Ligation of TLR9 induced on human IL-10-secreting Tregs by 1alpha,25-dihydroxyvitamin D3 abrogates regulatory function
-
Feb
-
Urry Z, Xystrakis E, Richards DF, McDonald J, Sattar Z, Cousins DJ, et al. Ligation of TLR9 induced on human IL-10-secreting Tregs by 1alpha,25-dihydroxyvitamin D3 abrogates regulatory function. Clin Invest Feb 2009;119:387-98.
-
(2009)
Clin Invest
, vol.119
, pp. 387-398
-
-
Urry, Z.1
Xystrakis, E.2
Richards, D.F.3
McDonald, J.4
Sattar, Z.5
Cousins, D.J.6
-
8
-
-
70449368149
-
Induction of Treg by monocyte-derived DC modulated by vitamin D3 or dexamethasone: Differential role for PD-L1
-
Nov
-
Unger WW, Laban S, Kleijwegt FS, van der Slik AR, Roep BO. Induction of Treg by monocyte-derived DC modulated by vitamin D3 or dexamethasone: differential role for PD-L1. Eur J Immunol Nov 2009;39:3147-59.
-
(2009)
Eur J Immunol
, vol.39
, pp. 3147-3159
-
-
Unger, W.W.1
Laban, S.2
Kleijwegt, F.S.3
Van Der Slik, A.R.4
Roep, B.O.5
-
9
-
-
17644401678
-
Peptide-based therapeutic vaccines for allergic and autoimmune diseases
-
Larché Mark, Wraith David C. Peptide-based therapeutic vaccines for allergic and autoimmune diseases. Nat Med 2005;11:69-76.
-
(2005)
Nat Med
, vol.11
, pp. 69-76
-
-
Mark, L.1
Wraith David, C.2
-
10
-
-
33846446041
-
Anti-TNF-α therapy induces a distinct regulatory T cell population in patients with rheumatoid arthritis via TGF-β
-
DOI 10.1084/jem.20061531
-
Nadkarni S, Mauri C, Ehrenstein MR. Anti-TNF-α therapy induces a distinct regulatory T cell population in patients with rheumatoid arthritis via TGF-β. J Exp Med 2007;204:33-9. (Pubitemid 46148753)
-
(2007)
Journal of Experimental Medicine
, vol.204
, Issue.1
, pp. 33-39
-
-
Nadkarni, S.1
Mauri, C.2
Ehrenstein, M.R.3
-
11
-
-
74849091357
-
Novel role of plasmacytoid dendritic cells in humans: Induction of interleukin-10-producing Treg cells by plasmacytoid dendritic cells in patients with rheumatoid arthritis responding to therapy
-
Kavousanaki M, Makrigiannakis A, Boumpas D, Verginis P. Novel role of plasmacytoid dendritic cells in humans: induction of interleukin-10-producing Treg cells by plasmacytoid dendritic cells in patients with rheumatoid arthritis responding to therapy. Arthritis Rheum Jan 2010;62:53-63.
-
(2010)
Arthritis Rheum Jan
, vol.62
, pp. 53-63
-
-
Kavousanaki, M.1
Makrigiannakis, A.2
Boumpas, D.3
Verginis, P.4
-
12
-
-
33744933432
-
A phase I trial with transgenic bacteria expressing interleukin-10 in crohn's disease
-
DOI 10.1016/j.cgh.2006.03.028, PII S1542356506003314
-
Braat H, Rottiers P, Hommes DW, Huyghebaert N, Remaut E, Remon JP, et al. A Phase I trial with transgenic bacteria expressing Interleukin-10 in Crohn's disease. Clin Gastroenterol Hepatol 2006;4:754-9. (Pubitemid 43841860)
-
(2006)
Clinical Gastroenterology and Hepatology
, vol.4
, Issue.6
, pp. 754-759
-
-
Braat, H.1
Rottiers, P.2
Hommes, D.W.3
Huyghebaert, N.4
Remaut, E.5
Remon, J.6
Van Deventer, S.J.H.7
Neirynck, S.8
Peppelenbosch, M.P.9
Steidler, L.10
-
13
-
-
40749155409
-
Autoantigenspecific IL-10-transduced T cells suppress chronic arthritis by promoting the endogenous regulatory IL-10 response
-
Guichelaar T, Brink C,Kooten PJ, Berlo SE, Broeren CP, van Eden W, et al. Autoantigenspecific IL-10-transduced T cells suppress chronic arthritis by promoting the endogenous regulatory IL-10 response. J Immunol 2008;180:1373-81.
-
(2008)
J Immunol
, vol.180
, pp. 1373-1381
-
-
Guichelaar, T.1
Brink Ckooten, P.J.2
Berlo, S.E.3
Broeren, C.P.4
Van Eden, W.5
-
14
-
-
77649107244
-
Discussion: DMARDs and biologic therapies in the management of inflammatory joint diseases
-
May
-
Vaz A, Lisse J, Rizzo W, Albani S. Discussion: DMARDs and biologic therapies in the management of inflammatory joint diseases. Expert Rev Clin Immunol May 2009;5(3):291-9.
-
(2009)
Expert Rev Clin Immunol
, vol.5
, Issue.3
, pp. 291-299
-
-
Vaz, A.1
Lisse, J.2
Rizzo, W.3
Albani, S.4
-
15
-
-
77958020350
-
Rheumatoid arthritis therapy: Advances from bench to bedside
-
Choi SI, Brahn E. Rheumatoid arthritis therapy: advances from bench to bedside. Autoimmunity 2010;43(7):478-82.
-
(2010)
Autoimmunity
, vol.43
, Issue.7
, pp. 478-482
-
-
Choi, S.I.1
Brahn, E.2
-
16
-
-
70349969840
-
Regulatory T cells as therapeutic targets in rheumatoid arthritis
-
Oct
-
Esensten JH, Wofsy D, Bluestone JA. Regulatory T cells as therapeutic targets in rheumatoid arthritis. Nat Rev Rheumatol Oct 2009;5:560-5.
-
(2009)
Nat Rev Rheumatol
, vol.5
, pp. 560-565
-
-
Esensten, J.H.1
Wofsy, D.2
Bluestone, J.A.3
-
17
-
-
63549084142
-
Clinical grade production of IL-10 producing regulatory Tr1 lymphocytes for cell therapy of chronic inflammatory diseases
-
May
-
Brun V, Bastian H, Neveu V, Foussat A. Clinical grade production of IL-10 producing regulatory Tr1 lymphocytes for cell therapy of chronic inflammatory diseases. Int Immunopharmacol May 2009;9(5):609-13.
-
(2009)
Int Immunopharmacol
, vol.9
, Issue.5
, pp. 609-613
-
-
Brun, V.1
Bastian, H.2
Neveu, V.3
Foussat, A.4
-
18
-
-
0029906583
-
+ T cells
-
DOI 10.1073/pnas.93.25.14736
-
Cai Z, Brunmark A, Jackson MR, Loh D, Peterson PA, Sprent J. Transfected Drosophila cells as a probe for defining the minimal requirements for stimulating unprimed CD8+ T cells. Proc Natl Acad Sci USA Dec 10 1996;93:14736-41. (Pubitemid 26419038)
-
(1996)
Proceedings of the National Academy of Sciences of the United States of America
, vol.93
, Issue.25
, pp. 14736-14741
-
-
Cai, Z.1
Brunmark, A.2
Jackson, M.R.3
Loh, D.4
Peterson, P.A.5
Sprent, J.6
-
19
-
-
2942685507
-
Immune responses in healthy and allergic individuals are characterized by a fine balance between allergen-specific T regulatory 1 and T helper 2 cells
-
DOI 10.1084/jem.20032058
-
Akdis M, Verhagen J, Taylor A, Karamloo F, Karagiannidis C, Crameri R, et al. Immune responses in healthy and allergic individuals are characterized by a fine balance between allergen-specific T regulatory 1 and T helper 2 cells. J Exp Med Jun 7 2004;199:1567-75. (Pubitemid 38780411)
-
(2004)
Journal of Experimental Medicine
, vol.199
, Issue.11
, pp. 1567-1575
-
-
Akdis, M.1
Verhagen, J.2
Taylor, A.3
Karamloo, F.4
Karagiannidis, C.5
Crameri, R.6
Thunberg, S.7
Deniz, G.8
Valenta, R.9
Fiebig, H.10
Kegel, C.11
Disch, R.12
Schmidt-Weber, C.B.13
Blaser, K.14
Akdis, C.A.15
-
20
-
-
9144221452
-
Presence of diabetes-inhibiting, glutamic acid decarboxylase-specific, IL-10-dependent, regulatory T cells in naive nonobese diabetic mice
-
You S, Chen C, Lee WH, Brusko T, Atkinson M, Liu CP. Presence of diabetesinhibiting, glutamic acid decarboxylase-specific, IL-10-dependent, regulatory T cells in naive nonobese diabetic mice. J Immunol Dec 1 2004;173:6777-85. (Pubitemid 39541064)
-
(2004)
Journal of Immunology
, vol.173
, Issue.11
, pp. 6777-6785
-
-
You, S.1
Chen, C.2
Lee, W.-H.3
Brusko, T.4
Atkinson, M.5
Liu, C.-P.6
-
21
-
-
0037261145
-
+ T cells from the target organ of patients with rheumatoid arthritis
-
DOI 10.1002/immu.200390024
-
Cao D, Malmström V, Baecher-Allan C, Hafler D, Klareskog L, Trollmo C. Isolation and functional characterization of regulatory CD25brightCD4+ T cells from the target organ of patients with rheumatoid arthritis. Eur J Immunol Jan 2003;33: 215-23. (Pubitemid 36157659)
-
(2003)
European Journal of Immunology
, vol.33
, Issue.1
, pp. 215-223
-
-
Cao, D.1
Malmstrom, V.2
Baecher-Allan, C.3
Hafler, D.4
Klareskog, L.5
Trollmo, C.6
-
22
-
-
33646370647
-
hi T-regulatory cells
-
DOI 10.1182/blood-2005-11-4567
-
Valencia X, Stephens G, Goldbach-Mansky R, Wilson M, Shevach E, Lipsky PE. TNF downmodulates the function of human CD4+CD25hi T-regulatory cells. Blood 2006: 253-61. (Pubitemid 43990636)
-
(2006)
Blood
, vol.108
, Issue.1
, pp. 253-261
-
-
Valencia, X.1
Stephens, G.2
Goldbach-Mansky, R.3
Wilson, M.4
Shevach, E.M.5
Lipsky, P.E.6
-
23
-
-
33845948381
-
+ T cell regulatory functions
-
Wan S, Xia C, Morel L. IL-6 produced by dendritic cells from lupus-prone mice inhibits CD4+ CD25+ T cell regulatory functions. J Immunol 2007;178:271-9. (Pubitemid 46033610)
-
(2007)
Journal of Immunology
, vol.178
, Issue.1
, pp. 271-279
-
-
Wan, S.1
Xia, C.2
Morel, L.3
-
24
-
-
33846196712
-
+ T lymphocytes
-
Peluso I, Fantini MC, Fina D, Caruso R, Boirivant M, MacDonald TT, et al. IL-21 counteracts the regulatory T cell-mediated suppression of human CD4+ T lymphocytes. J Immunol Jan 15 2007;178:732-9. (Pubitemid 46095145)
-
(2007)
Journal of Immunology
, vol.178
, Issue.2
, pp. 732-739
-
-
Peluso, I.1
Fantini, M.C.2
Fina, D.3
Caruso, R.4
Boirivant, M.5
MacDonald, T.T.6
Pallone, F.7
Monteleone, G.8
-
25
-
-
0037436119
-
+ T cell-mediated suppression by dendritic cells
-
DOI 10.1126/science.1078231
-
Pasare C, Medzhitov R. Toll pathway-dependent blockade of CD4+ CD25+ T cell-mediated suppression by dendritic cells. Science 2003;299:1033-6. (Pubitemid 36222922)
-
(2003)
Science
, vol.299
, Issue.5609
, pp. 1033-1036
-
-
Pasare, C.1
Medzhitov, R.2
-
26
-
-
35848964590
-
Abnormal Tr1 differentiation in multiple sclerosis
-
DOI 10.1016/j.jneuroim.2007.09.018, PII S0165572807003177, Regulation of Neuroinflammation
-
Astier AL, Hafler DA. Abnormal Tr1 differentiation in multiple sclerosis. J Neuroimmunol Nov 2007;191(1-2):70-8. (Pubitemid 350061001)
-
(2007)
Journal of Neuroimmunology
, vol.191
, Issue.1-2
, pp. 70-78
-
-
Astier, A.L.1
Hafler, D.A.2
-
27
-
-
77953339908
-
A defect of CD4+CD25+ regulatory T cells in inducing interleukin-10 production from CD4+ T cells under CD46 costimulation in asthma patients
-
May
-
Xu YQ, Gao YD, Yang J, Guo W. A defect of CD4+CD25+ regulatory T cells in inducing interleukin-10 production from CD4+ T cells under CD46 costimulation in asthma patients. J Asthma May 2010;47(4):367-73.
-
(2010)
J Asthma
, vol.47
, Issue.4
, pp. 367-373
-
-
Xu, Y.Q.1
Gao, Y.D.2
Yang, J.3
Guo, W.4
-
28
-
-
33644550620
-
Inhibition of the transcription factor Foxp3 converts desmoglein 3-specific type 1 regulatory T cells into Th2-like cells
-
Mar 1
-
Veldman C, Pahl A, Beissert S, Hansen W, Buer J, Dieckmann D, et al. Inhibition of the transcription factor Foxp3 converts desmoglein 3-specific type 1 regulatory T cells into Th2-like cells. J Immunol Mar 1 2006;176(5):3215-22.
-
(2006)
J Immunol
, vol.176
, Issue.5
, pp. 3215-3222
-
-
Veldman, C.1
Pahl, A.2
Beissert, S.3
Hansen, W.4
Buer, J.5
Dieckmann, D.6
-
29
-
-
0041915628
-
Induction of a regulatory T cell type I response reduces the development of atherosclerosis in apolipoprotein E-knockout mice
-
DOI 10.1161/01.CIR.0000089083.61317.A1
-
Mallat Z, Gojova A, Brun V, Esposito B, Fournier N, Cottrez F, et al. Induction of a regulatory T cell type 1 response reduces the development of atherosclerosis in apolipoprotein E-knockout mice. Circulation 2003;108:1232-7. (Pubitemid 37099993)
-
(2003)
Circulation
, vol.108
, Issue.10
, pp. 1232-1237
-
-
Mallat, Z.1
Gojova, A.2
Brun, V.3
Esposito, B.4
Fournier, N.5
Cottrez, F.6
Tedgui, A.7
Groux, H.8
-
30
-
-
71649087238
-
IL-10 suppresses Th17 cells and promotes regulatory T cells in the CD4+ T cell population of rheumatoid arthritis patients
-
Jan 4
-
Heo YJ, Joo YB, Oh HJ, Park MK, Heo YM, Cho ML, et al. IL-10 suppresses Th17 cells and promotes regulatory T cells in the CD4+ T cell population of rheumatoid arthritis patients. Immunol Lett Jan 4 2010;127:150-6.
-
(2010)
Immunol Lett
, vol.127
, pp. 150-156
-
-
Heo, Y.J.1
Joo, Y.B.2
Oh, H.J.3
Park, M.K.4
Heo, Y.M.5
Cho, M.L.6
-
31
-
-
77952239724
-
Adoptive transfer of IL-10-secreting CD4+CD49b+regulatory T cells suppresses ongoing arthritis
-
Jun
-
Charbonnier LM, Han WG, Quentin J, Huizinga TW, Zwerina J, Toes RE, et al. Adoptive transfer of IL-10-secreting CD4+CD49b+regulatory T cells suppresses ongoing arthritis. J Autoimmun Jun 2010;34:390-9.
-
(2010)
J Autoimmun
, vol.34
, pp. 390-399
-
-
Charbonnier, L.M.1
Han, W.G.2
Quentin, J.3
Huizinga, T.W.4
Zwerina, J.5
Toes, R.E.6
|