All-trans retinoic acid induces cellular senescence by up-regulating levels of p16 and p21 via promoter hypomethylation

Biochemical and Biophysical Research Communications

Volumn 412, Issue 3, 2011, Pages 500-505

  Lim, Joo Song ^a   Park, Sun Hye ^a   Jang, Kyung Lib ^a  

^a Pusan National University   (South Korea)

Author keywords

All trans retinoic acid; Cellular senescence; DNA methylation; P16; P21; Retinoic acid receptor 2

Indexed keywords

DNA; DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3A; DNA METHYLTRANSFERASE 3B; PROTEIN P16; PROTEIN P21; RETINOIC ACID; RETINOIC ACID RECEPTOR BETA;

ARTICLE; CANCER THERAPY; CELL AGING; CELL STRAIN HEPG2; CONTROLLED STUDY; DNA METHYLATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN BINDING; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION;

CELL AGING; CYCLIN-DEPENDENT KINASE INHIBITOR P16; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; HEP G2 CELLS; HUMANS; PROMOTER REGIONS, GENETIC; PROTO-ONCOGENE PROTEIN C-ETS-1; PROTO-ONCOGENE PROTEIN C-ETS-2; RECEPTORS, RETINOIC ACID; TRETINOIN;

EID: 84860397057     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.07.130     Document Type: Article

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