A DNA vaccine encoding foot-and-mouth disease virus B and T-cell epitopes targeted to class II swine leukocyte antigens protects pigs against viral challenge

Antiviral Research

Volumn 92, Issue 2, 2011, Pages 359-363

  Borrego, Belén ^a   Argilaguet, Jordi M ^b   Pérez Martín, Eva ^b   Dominguez, Javier ^c   Pérez Filgueira, Mariano ^c   Escribano, José M ^c   Sobrino, Francisco ^a,d   Rodriguez, Fernando ^b  

^a Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria Consejo Superior de Investigaciones Científicas   (Spain)

^b CENTRE DE RECERCA EN SANITAT ANIMAL CRESA   (Spain)

^c INIA   (Spain)

^d UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

Author keywords

DNA vaccine; FMDV; Neutralizing antibody; ScFv; T cell

Indexed keywords

FOOT AND MOUTH DISEASE VACCINE; GAMMA INTERFERON; HLA A2 ANTIGEN; MONOCLONAL ANTIBODY; NEUTRALIZING ANTIBODY;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; B LYMPHOCYTE; CONTROLLED STUDY; DNA IMMUNIZATION; DRUG EFFICACY; FOOT AND MOUTH DISEASE; FOOT AND MOUTH DISEASE VIRUS; INFECTION PREVENTION; NONHUMAN; PRIORITY JOURNAL; SWINE; T LYMPHOCYTE; TREATMENT RESPONSE; VIRUS IMMUNITY; VIRUS ISOLATION; VIRUS LOAD; VIRUS NEUTRALIZATION; VIRUS REPLICATION;

ANIMALS; ANTIBODIES, NEUTRALIZING; ANTIBODIES, VIRAL; EPITOPES, B-LYMPHOCYTE; EPITOPES, T-LYMPHOCYTE; FOOT-AND-MOUTH DISEASE; FOOT-AND-MOUTH DISEASE VIRUS; HISTOCOMPATIBILITY ANTIGENS CLASS II; INTERFERON-GAMMA; RECOMBINANT FUSION PROTEINS; SINGLE-CHAIN ANTIBODIES; SWINE; SWINE DISEASES; T-LYMPHOCYTES; VACCINES, DNA; VACCINES, SYNTHETIC;

ANIMALIA; FOOT-AND-MOUTH DISEASE VIRUS; MUS; SUIDAE;

EID: 84860389922     PISSN: 01663542     EISSN: 18729096     Source Type: Journal    
DOI: 10.1016/j.antiviral.2011.07.017     Document Type: Article

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