Relationship between clinical signs and transmission of an infectious disease and the implications for control

Science

Volumn 332, Issue 6030, 2011, Pages 726-729

  Charleston, Bryan ^a   Bankowski, Bartlomies M ^a   Gubbins, Simon ^a   Chase Topping, Margo E ^b   Schley, David ^a   Howey, Richard ^b   Barnett, Paul V ^a   Gibson, Debi ^a   Juleff, Nicholas D ^a   Woolhouse, Mark E J ^b  

^a INSTITUTE FOR ANIMAL HEALTH   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BODY FLUID; CATTLE; DISEASE CONTROL; DISEASE TRANSMISSION; EXPERIMENTAL STUDY; INFECTIOUS DISEASE; VIRUS;

ANIMAL MODEL; ARTICLE; BODY FLUID; CATTLE DISEASE; CONTROLLED STUDY; DISEASE TRANSMISSION; EXPERIMENTAL STUDY; FOOT AND MOUTH DISEASE; INFECTION CONTROL; NONHUMAN; PRIORITY JOURNAL; VIRUS DETECTION;

ANIMALS; ANTIBODIES, VIRAL; BAYES THEOREM; CATTLE; CATTLE DISEASES; COMMUNICABLE DISEASE CONTROL; FOOT-AND-MOUTH DISEASE; FOOT-AND-MOUTH DISEASE VIRUS; TIME FACTORS; VIREMIA; VIRUS LATENCY;

ANIMALIA; BOS;

EID: 79955767867     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1199884     Document Type: Article

References (23)

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23. We thank L. Fitzpatrick, C. Randal, and M. Jenkins for their assistance with the handling and management of experimental animals; P. Hamblin and P. Keel for help and advice with serology assays; L. Reid, M. Windsor, and S. Cox for assistance with laboratory assays; S. Alexandersen, D. Paton, and N. Savill for valuable advice on study design; and B. Grenfell, M. Keeling, M. de Jong, A. Graham, C. Dye, and four anonymous referees for insightful comments. The work was funded by the Biotechnology and Biological Sciences Research Council (grant BBSB00549), UK. B.C. and P.V.B. are Jenner Investigators. S.G. and D.S. acknowledge funding from the Biotechnology and Biological Sciences Research Council (grant BBSEI00001444). M.E.C.T. is partly supported by the Wellcome Trust.