Disturbance of Ca2+ homeostasis converts pro-Met into non-canonical tyrosine kinase p190MetNCin response to endoplasmic reticulum stress in MHCC97 cells

Journal of Biological Chemistry

Volumn 287, Issue 18, 2012, Pages 14586-14597

  Dai, Rongyang ^a,b,c   Li, Juanjuan ^a   Fu, Jing ^a   Chen, Yao ^a   Yu, Lexing ^a   Zhao, Xiaofang ^a   Qian, Youwen ^a   Zhang, Huilu ^a   Chen, Haiyang ^a   Ren, Yibin ^a   Su, Bo ^a   Luo, Tao ^a   Zhu, Junjie ^a   Wang, Hongyang ^a,b  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b SHANGHAI JIAO TONG UNIVERSITY   (China)

^c SOUTHWEST MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM HOMEOSTASIS; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; ER STRESS; HEPATOCELLULAR CARCINOMA; HEPATOCYTE GROWTH FACTOR; MICROENVIRONMENTS; POTENTIAL MECHANISM; THAPSIGARGINS; TUMORIGENESIS; TYROSINE KINASE; UNDERLYING MECHANISM;

AMINO ACIDS; CELL DEATH; CELL MEMBRANES; CHEMICAL COMPOUNDS; ENZYMES; GLUCOSE; PEPTIDES; PHYSIOLOGY;

CALCIUM;

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CALCIUM ION; CRIZOTINIB; CYTOKINE RECEPTOR; GLUCOSE REGULATED PROTEIN 78; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN P190METALPHABETA; PROTEIN P190METNC; PROTEIN PRECURSOR; SCATTER FACTOR; SCATTER FACTOR RECEPTOR; SCATTER FACTOR RECEPTOR PRECURSOR; UNCLASSIFIED DRUG; CALCIUM; ENZYME INHIBITOR; MERTK PROTEIN, HUMAN; ONCOPROTEIN; PROTEIN TYROSINE KINASE; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; THAPSIGARGIN;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CALCIUM HOMEOSTASIS; CANCER CELL CULTURE; CELL PROTECTION; CELL SURVIVAL; CONTROLLED STUDY; DRUG POTENTIATION; DRUG SELECTIVITY; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER CELL CARCINOMA; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PROCESSING; BIOSYNTHESIS; DRUG EFFECT; ENZYMOLOGY; FEMALE; GENE EXPRESSION REGULATION; GENETICS; HOMEOSTASIS; LIVER TUMOR; MALE; METABOLISM; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

CALCIUM; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CELL SURVIVAL; ENDOPLASMIC RETICULUM STRESS; ENZYME INHIBITORS; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HOMEOSTASIS; HUMANS; LIVER NEOPLASMS; MALE; PROTEOLYSIS; PROTO-ONCOGENE PROTEINS; RECEPTOR PROTEIN-TYROSINE KINASES; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES; SIGNAL TRANSDUCTION; THAPSIGARGIN;

EID: 84860370146     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.333435     Document Type: Article

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