Kif2C minimal functional domain has unusual nucleotide binding properties that are adapted to microtubule depolymerization

Journal of Biological Chemistry

Volumn 287, Issue 18, 2012, Pages 15143-15153

  Wang, Weiyi ^a   Jiang, Qiyang ^a   Argentini, Manuela ^b   Cornu, David ^b   Gigant, Benoît ^c   Knossow, Marcel ^c   Wang, Chunguang ^a  

^a TONGJI UNIVERSITY   (China)

^b CNRS   (France)

^c LABORATOIRE D ENZYMOLOGIE ET BIOCHIMIE STRUCTURALES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE NUCLEOTIDE; ATP HYDROLYSIS; BINDING SPECIFICITIES; CONFORMATIONAL STATE; DEPOLYMERASE; FUNCTIONAL DOMAINS; HETERODIMERS; KINESINS; MICROTUBULES; MOTOR DOMAIN; N-TERMINALS; NUCLEOTIDE BINDING; NUCLEOTIDE-BINDING SITES; PHYSIOLOGICAL CONCENTRATIONS;

BINDING ENERGY;

NUCLEOTIDES;

ADENINE; ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; KINESIN; KINESIN 13 KIF2C; TUBULIN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DEPOLYMERIZATION; ENZYME ACTIVATION; ENZYME SPECIFICITY; HYDROLYSIS; MICROTUBULE; MICROTUBULE ASSEMBLY; NUCLEOTIDE BINDING SITE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY;

ADENOSINE TRIPHOSPHATE; ANIMALS; BINDING SITES; HUMANS; HYDROLYSIS; KINESIN; MICROTUBULES; MODELS, BIOLOGICAL; PROTEIN BINDING; PROTEIN MULTIMERIZATION; SWINE; TUBULIN;

EID: 84860357530     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.317859     Document Type: Article

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