Coupling of kinesin steps to ATP hydrolysis

Nature

Volumn 388, Issue 6640, 1997, Pages 390-393

  Hua, Wei ^a   Young, Edgar C ^a   Fleming, Margaret L ^a   Gelles, Jeff ^a  

^a BRANDEIS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE;

ARTICLE; HYDROLYSIS; MICROTUBULE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY;

ADENOSINE TRIPHOSPHATASES; ADENOSINE TRIPHOSPHATE; ANIMALS; DROSOPHILA; HYDROLYSIS; KINESIN; MICROSCOPY, INTERFERENCE; MICROSCOPY, VIDEO; MICROSPHERES; MICROTUBULES; MONTE CARLO METHOD; MOVEMENT; RECOMBINANT FUSION PROTEINS;

EID: 0030844286     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/41118     Document Type: Article

References (29)

1. Taylor, E. W. Variations on the theme of movement. Nature 361, 115-116 (1993).
2. Ishijima, A. et al. Single-molecule analysis of the actomyosin motor using nano-manipulation. Biochem. Biophys. Res. Commun. 199, 1057-1063 (1994).
3. Hackney, D. D. Evidence for alternating head catalysis by kinesin during microtubule-stimulated ATP hydrolysis. Proc. Natl Acad. Sci. USA 91, 6865-6869 (1994).
4. Svoboda, K., Schmidt, C. F., Schnapp, B. J. & Block, S. M. Direct observation of kinesin stepping by optical trapping interferometry. Nature 365, 721-727 (1993).
5. Coppin, C. M., Finer, J. T., Spudich, J. A. & Vale, R. D. Detection of sub-8-nm movements of kinesin by high-resolution optical-trap microscopy. Proc. Natl Acad. Sci. USA 93, 1913-1917 (1996).
6. Gelles, J., Schnapp, B. J. & Sheetz, M. P. Tracking kinesin-driven movements with nanometre-scale precision. Nature 331, 450-453 (1988).
7. Beese, L., Stubbs, G. & Cohen, C. Microtubule structure at 18 Å resolution. J. Mol. Biol. 194, 257-264 (1987).
8. Stewart, R. J., Thaler, J. P. & Goldstein, L. S. B. Direction of microtubule movement is an intrinsic property of the motor domains of kinesin heavy chain and Drosophila ncd protein. Proc. Natl Acad. Sci. USA 90, 5209-5213 (1993).
9. Young, E. C., Berliner, E., Mahtani, H. K., Perez-Ramirez, B. & Gelles, J. Subunit interactions in dimeric kinesin heavy chain derivatives that lack the kinesin rod. J. Biol. Chem. 270, 3926-3931 (1995).
10. Scholey, J. M., Heuser, J., Yang, J. T. & Goldstein, L. S. B. Identification of globular mechanochemical heads of kinesin. Nature 338, 355-357 (1989).
11. Berliner, E., Young, E. C., Anderson, K., Mahtani, H. K. & Gelles, J. Failure of a single-headed kinesin to track parallel to microtubule protofilaments. Nature 373, 718-721 (1995).
12. Berliner, E. thesis, Brandeis Univ. Waltham, MA (1995).
13. Howard, J., Hudspeth, A. J. & Vale, R. D. Movement of microtubules by single kinesin molecules. Nature 342, 154-158 (1989).
14. Block, S. M., Goldstein, L. S. B. & Schnapp, B. J. Bead movement by single kinesin molecules studied with optical tweezers. Nature 348, 348-352 (1990).
15. Vale, R. D. et al. Direct observation of single kinesin molecules moving along microtubules. Nature 380, 451-453 (1996).
16. Segel, I. H. Enzyme Kinetics (Wiley, New York, 1975).
17. Gilbert, S. P., Webb, M. R., Brune, M. & Johnson, K. A. Pathway of processive ATP hydrolysis by kinesin. Nature 373, 671-676 (1995).
18. Ma, Y.-Z. & Taylor, E. W. Mechanism of microtubule kinesin ATPase. Biochemistry 34, 13242-13251 (1995).
19. Arnal, I., Metoz, F., DeBonis, S. & Wade, R. Three-dimensional structure of functional motor proteins on microtubules. Curr. Biol. 6, 1265-1270 (1996).
20. Hirose, K., Lockhart, A., Cross, R. A. & Amos, L. A. Three-dimensional cryoelectron microscopy of dimeric kinesin and ncd motor domains on microtubules. Proc. Natl Acad. Sci. USA 93, 9539-9544 (1996).
21. Hirose, K., Lockhart, A., Cross, R. A. & Amos, L. A. Nucleotide-dependent angular change in kinesin motor domain bound to tubulin. Nature 376, 277-279 (1995).
22. Kikkawa, M., Ishikawa, T., Wakabayashi, T. & Hirokawa, N. Three-dimensional structure of the kinesin head-microtubule complex. Nature 376, 274-276 (1995).
23. Ray, S., Meyhoefer, E., Milligan, R. A. & Howard, J. Kinesin follows the microtubule's protofilament axis. J. Cell Biol. 121, 1083-1093 (1993).
24. Gelles, J. et al. Structural and functional features of one- and two-headed biotinated kinesin derivatives. Biophys. J. 68, 276s-282s (1995).
25. Berliner, E. et al. Microtubule movement by a biotinated kinesin bound to a streptavidin-coated surface. J. Biol. Chem. 269, 8610-8615 (1994).
26. Hackney, D. D., Malik, A.-S. & Wright, K. W. Nucleotide-free kinesin hydrolyzes ATP with burst kinetics. J. Biol. Chem. 264, 15943-15948 (1989).
27. Hackney, D. D. Kinesin ATPase: rate-limiting ADP release. Proc. Natl Acad. Sci. USA 85, 6314-6318 (1988).
28. Gallagher, N. C. Jr & Wise, G. L. A theoretical analysis of the properties of median filters. IEEE Trans. Acoust. Speech Signal Process. 29, 1136-1141 (1981).
29. Savitzky, A. & Golay, M. J. E. Smoothing and differentiation of data by simplified least squares procedures. Anal. Chem. 36, 1627-1639 (1964).