SCOPUS 정보 검색 플랫폼

Volumn 52, Issue , 2012, Pages 242-250

The conversion of oridonin to spirolactone-type or enmein-type diterpenoid: Synthesis and biological evaluation of ent-6,7-seco-oridonin derivatives as novel potential anticancer agents

(8) Wang, Lei a Li, Dahong a Xu, Shengtao a Cai, Hao a Yao, Hequan a Zhang, Yihua a Jiang, Jieyun b Xu, Jinyi a

a CHINA PHARMACEUTICAL UNIVERSITY (China)

b UNIVERSITY OF KENTUCKY (United States)

Author keywords

Anti tumor activity; Cytotoxicity; Enmein type diterpenoid; ent 6,7 seco Oridonin derivatives; Spirolactone type diterpenoid; Structure activity relationship

Indexed keywords

DITERPENOID; ENT 1,6,7,15 TETRAOXO 7,20 EPOXY 6,7 SECO 16 KAURENE; ENT 14ALPHA HYDROXY 1,7 EPOXY 6,7,15 TRIOXO 6,20 EPOXY 6,7 SECO 16 KAURENE; ENT 1ALPHA O ACETYL 14BETA HYDROXY 6,7,15 TRIOXO 7,20 EPOXY 6,7 SECO 16 KAURENE; ENT 6BETA,14ALPHA DIHYDROXY 1,7 EPOXY 7,15 DIOXO 6,20 HEMIKETAL 6,7 SECO 16 KAURENE; ORIDONIN; PACLITAXEL; SPIRONOLACTONE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG DESIGN; DRUG SYNTHESIS; FEMALE; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; STOMACH CANCER; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTINEOPLASTIC AGENTS; CHEMISTRY TECHNIQUES, SYNTHETIC; DITERPENES; DITERPENES, KAURANE; FEMALE; HUMANS; K562 CELLS; MICE; SPIRONOLACTONE; STRUCTURE-ACTIVITY RELATIONSHIP; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84860351057 PISSN: 02235234 EISSN: 17683254 Source Type: Journal
DOI: 10.1016/j.ejmech.2012.03.024 Document Type: Article

Times cited : (64)

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